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Items: 1 to 20 of 46


MDM2 SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients.

Deben C, Op de Beeck K, Van den Bossche J, Jacobs J, Lardon F, Wouters A, Peeters M, Van Camp G, Rolfo C, Deschoolmeester V, Pauwels P.

J Cancer. 2017 Jul 15;8(12):2154-2162. doi: 10.7150/jca.19254. eCollection 2017.


Towards Prognostic Profiling of Non-Small Cell Lung Cancer: New Perspectives on the Relevance of Polo-Like Kinase 1 Expression, the TP53 Mutation Status and Hypoxia.

Van den Bossche J, Deben C, Op de Beeck K, Deschoolmeester V, Hermans C, De Pauw I, Jacobs J, Van Schil P, Vermorken JB, Pauwels P, Peeters M, Lardon F, Wouters A.

J Cancer. 2017 May 12;8(8):1441-1452. doi: 10.7150/jca.18455. eCollection 2017.


Primary tumor sidedness has an impact on prognosis and treatment outcome in metastatic colorectal cancer: results from two randomized first-line panitumumab studies.

Boeckx N, Koukakis R, Op de Beeck K, Rolfo C, Van Camp G, Siena S, Tabernero J, Douillard JY, André T, Peeters M.

Ann Oncol. 2017 Aug 1;28(8):1862-1868. doi: 10.1093/annonc/mdx119.


Whole-body diffusion-weighted magnetic resonance imaging in the diagnosis of recurrent ovarian cancer: a clinical feasibility study.

Michielsen KL, Vergote I, Dresen R, Op de Beeck K, Vanslembrouck R, Amant F, Leunen K, Moerman P, Fieuws S, De Keyzer F, Vandecaveye V.

Br J Radiol. 2016 Nov;89(1067):20160468. Epub 2016 Sep 21.


Malformations of the middle and inner ear on CT imaging in 22q11 deletion syndrome.

Loos E, Verhaert N, Willaert A, Devriendt K, Swillen A, Hermans R, Op de Beeck K, Hens G.

Am J Med Genet A. 2016 Nov;170(11):2975-2983. doi: 10.1002/ajmg.a.37872. Epub 2016 Sep 8.


The Genetic Landscape of Malignant Pleural Mesothelioma: Results from Massively Parallel Sequencing.

Hylebos M, Van Camp G, van Meerbeeck JP, Op de Beeck K.

J Thorac Oncol. 2016 Oct;11(10):1615-26. doi: 10.1016/j.jtho.2016.05.020. Epub 2016 Jun 6. Review.


Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway.

Heyninck K, Sabbe L, Chirumamilla CS, Szarc Vel Szic K, Vander Veken P, Lemmens KJ, Lahtela-Kakkonen M, Naulaerts S, Op de Beeck K, Laukens K, Van Camp G, Weseler AR, Bast A, Haenen GR, Haegeman G, Vanden Berghe W.

Biochem Pharmacol. 2016 Jun 1;109:48-61. doi: 10.1016/j.bcp.2016.03.026. Epub 2016 Apr 1.


APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines.

Deben C, Lardon F, Wouters A, Op de Beeck K, Van den Bossche J, Jacobs J, Van Der Steen N, Peeters M, Rolfo C, Deschoolmeester V, Pauwels P.

Cancer Lett. 2016 Jun 1;375(2):313-322. doi: 10.1016/j.canlet.2016.03.017. Epub 2016 Mar 11.


Role of DFNA5 in hearing loss and cancer - a comment on Rakusic et al.

Croes L, Op de Beeck K, Van Camp G.

Onco Targets Ther. 2015 Sep 15;8:2613-5. doi: 10.2147/OTT.S91168. eCollection 2015. No abstract available.


Prognostic and Predictive Value of RAS Gene Mutations in Colorectal Cancer: Moving Beyond KRAS Exon 2.

Boeckx N, Peeters M, Van Camp G, Pauwels P, Op de Beeck K, Deschoolmeester V.

Drugs. 2015 Oct;75(15):1739-56. doi: 10.1007/s40265-015-0459-x. Review.


The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways.

Van Rossom S, Op de Beeck K, Hristovska V, Winderickx J, Van Camp G.

Front Cell Neurosci. 2015 Jul 16;9:231. doi: 10.3389/fncel.2015.00231. eCollection 2015.


The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer.

Deben C, Wouters A, Op de Beeck K, van Den Bossche J, Jacobs J, Zwaenepoel K, Peeters M, Van Meerbeeck J, Lardon F, Rolfo C, Deschoolmeester V, Pauwels P.

Oncotarget. 2015 Sep 8;6(26):22666-79.


Whole-exome characterization of pancreatic neuroendocrine tumor cell lines BON-1 and QGP-1.

Vandamme T, Peeters M, Dogan F, Pauwels P, Van Assche E, Beyens M, Mortier G, Vandeweyer G, de Herder W, Van Camp G, Hofland LJ, Op de Beeck K.

J Mol Endocrinol. 2015 Apr;54(2):137-47. doi: 10.1530/JME-14-0304. Epub 2015 Jan 22.


Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells.

Palagani A, Op de Beeck K, Naulaerts S, Diddens J, Sekhar Chirumamilla C, Van Camp G, Laukens K, Heyninck K, Gerlo S, Mestdagh P, Vandesompele J, Berghe WV.

PLoS One. 2014 Dec 4;9(12):e113842. doi: 10.1371/journal.pone.0113842. eCollection 2014.


CT diagnosis of a post-embolization ischemic diverticulitis of Meckel.

De Beule T, Op de Beeck K, De Hertogh G, Sergeant G, Maleux G.

Acta Radiol Short Rep. 2014 Oct 7;3(9):2047981614531954. doi: 10.1177/2047981614531954. eCollection 2014 Oct.


Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins.

Boeckx C, Op de Beeck K, Wouters A, Deschoolmeester V, Limame R, Zwaenepoel K, Specenier P, Pauwels P, Vermorken JB, Peeters M, Van Camp G, Baay M, Lardon F.

Cancer Lett. 2014 Nov 28;354(2):365-77. doi: 10.1016/j.canlet.2014.08.039. Epub 2014 Sep 2.


Reactive nodular fibrous pseudotumor: case report and review of the literature.

Salihi R, Moerman P, Timmerman D, Van Schoubroeck D, Op de Beeck K, Vergote I.

Case Rep Obstet Gynecol. 2014;2014:421234. doi: 10.1155/2014/421234. Epub 2014 Mar 30.


Imaging in otosclerosis: A pictorial review.

Purohit B, Hermans R, Op de Beeck K.

Insights Imaging. 2014 Apr;5(2):245-52. doi: 10.1007/s13244-014-0313-9. Epub 2014 Feb 9.


Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells.

Szarc vel Szic K, Op de Beeck K, Ratman D, Wouters A, Beck IM, Declerck K, Heyninck K, Fransen E, Bracke M, De Bosscher K, Lardon F, Van Camp G, Vanden Berghe W.

PLoS One. 2014 Feb 3;9(2):e87850. doi: 10.1371/journal.pone.0087850. eCollection 2014.


Chemoembolization for hepatocellular carcinoma: 1-month response determined with apparent diffusion coefficient is an independent predictor of outcome.

Vandecaveye V, Michielsen K, De Keyzer F, Laleman W, Komuta M, Op de beeck K, Roskams T, Nevens F, Verslype C, Maleux G.

Radiology. 2014 Mar;270(3):747-57. doi: 10.1148/radiol.13130591. Epub 2013 Dec 12.


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