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Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations.

Iwasawa C, Kuzumaki N, Suda Y, Kagawa R, Oka Y, Hattori N, Okano H, Narita M.

Mol Brain. 2019 Jan 18;12(1):5. doi: 10.1186/s13041-019-0426-7.


Hepatic Injury without Granulomatous Formation Associated with Intravesical Bacillus Calmette-Guérin Therapy.

Okano H, Asakawa H, Nose K, Tsuruga S, Tochio T, Kumazawa H, Isono Y, Tanaka H, Matsusaki S, Sase T, Saito T, Mukai K, Nishimura A, Usui M, Baba Y, Murata T.

Intern Med. 2019 Jan 10. doi: 10.2169/internalmedicine.2073-18. [Epub ahead of print]


Estimating the concentration of therapeutic range using disease-specific iPS cells: Low-dose rapamycin therapy for Pendred syndrome.

Hosoya M, Saeki T, Saegusa C, Matsunaga T, Okano H, Fujioka M, Ogawa K.

Regen Ther. 2018 Dec 17;10:54-63. doi: 10.1016/j.reth.2018.11.001. eCollection 2019 Jun.


LOTUS Inhibits Neuronal Apoptosis and Promotes Tract Regeneration in Contusive Spinal Cord Injury Model Mice.

Ito S, Nagoshi N, Tsuji O, Shibata S, Shinozaki M, Kawabata S, Kojima K, Yasutake K, Hirokawa T, Matsumoto M, Takei K, Nakamura M, Okano H.

eNeuro. 2018 Dec 14;5(5). pii: ENEURO.0303-18.2018. doi: 10.1523/ENEURO.0303-18.2018. eCollection 2018 Sep-Oct.


Treatment with a Gamma-Secretase Inhibitor Promotes Functional Recovery in Human iPSC- Derived Transplants for Chronic Spinal Cord Injury.

Okubo T, Nagoshi N, Kohyama J, Tsuji O, Shinozaki M, Shibata S, Kase Y, Matsumoto M, Nakamura M, Okano H.

Stem Cell Reports. 2018 Dec 11;11(6):1416-1432. doi: 10.1016/j.stemcr.2018.10.022. Epub 2018 Nov 29.


Selective Ablation of Tumorigenic Cells Following Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in Spinal Cord Injury.

Kojima K, Miyoshi H, Nagoshi N, Kohyama J, Itakura G, Kawabata S, Ozaki M, Iida T, Sugai K, Ito S, Fukuzawa R, Yasutake K, Renault-Mihara F, Shibata S, Matsumoto M, Nakamura M, Okano H.

Stem Cells Transl Med. 2018 Nov 28. doi: 10.1002/sctm.18-0096. [Epub ahead of print]


Subcutaneous Heparin Therapy for Patients with Cancer-Associated Stroke.

Kawano H, Honda Y, Amano T, Okano H, Suzuki R, Torii M, Unno Y, Shiokawa Y, Hirano T.

J Stroke Cerebrovasc Dis. 2019 Feb;28(2):399-404. doi: 10.1016/j.jstrokecerebrovasdis.2018.10.012. Epub 2018 Nov 5.


Concise Review: Laying the Groundwork for a First-In-Human Study of an Induced Pluripotent Stem Cell-Based Intervention for Spinal Cord Injury.

Tsuji O, Sugai K, Yamaguchi R, Tashiro S, Nagoshi N, Kohyama J, Iida T, Ohkubo T, Itakura G, Isoda M, Shinozaki M, Fujiyoshi K, Kanemura Y, Yamanaka S, Nakamura M, Okano H.

Stem Cells. 2019 Jan;37(1):6-13. doi: 10.1002/stem.2926. Epub 2018 Nov 12. Review.


The Japan Monkey Centre Primates Brain Imaging Repository for comparative neuroscience: an archive of digital records including records for endangered species.

Sakai T, Hata J, Ohta H, Shintaku Y, Kimura N, Ogawa Y, Sogabe K, Mori S, Okano HJ, Hamada Y, Shibata S, Okano H, Oishi K.

Primates. 2018 Nov;59(6):553-570. doi: 10.1007/s10329-018-0694-3. Epub 2018 Oct 24.


Astrocyte-Derived Exosomes Treated With a Semaphorin 3A Inhibitor Enhance Stroke Recovery via Prostaglandin D2 Synthase.

Hira K, Ueno Y, Tanaka R, Miyamoto N, Yamashiro K, Inaba T, Urabe T, Okano H, Hattori N.

Stroke. 2018 Oct;49(10):2483-2494. doi: 10.1161/STROKEAHA.118.021272.


T-type Calcium Channels Determine the Vulnerability of Dopaminergic Neurons to Mitochondrial Stress in Familial Parkinson Disease.

Tabata Y, Imaizumi Y, Sugawara M, Andoh-Noda T, Banno S, Chai M, Sone T, Yamazaki K, Ito M, Tsukahara K, Saya H, Hattori N, Kohyama J, Okano H.

Stem Cell Reports. 2018 Nov 13;11(5):1171-1184. doi: 10.1016/j.stemcr.2018.09.006. Epub 2018 Oct 18.


Versatile Roles of LKB1 Kinase Signaling in Neural Development and Homeostasis.

Kuwako KI, Okano H.

Front Mol Neurosci. 2018 Oct 2;11:354. doi: 10.3389/fnmol.2018.00354. eCollection 2018.


Continuous production of d-lactic acid from cellobiose in cell recycle fermentation using β-glucosidase-displaying Escherichia coli.

Aso Y, Tsubaki M, Dang Long BH, Murakami R, Nagata K, Okano H, Phuong Dung NT, Ohara H.

J Biosci Bioeng. 2018 Oct 10. pii: S1389-1723(18)30673-X. doi: 10.1016/j.jbiosc.2018.09.011. [Epub ahead of print]


Unidirectional monosynaptic connections from auditory areas to the primary visual cortex in the marmoset monkey.

Majka P, Rosa MGP, Bai S, Chan JM, Huo BX, Jermakow N, Lin MK, Takahashi YS, Wolkowicz IH, Worthy KH, Rajan R, Reser DH, Wójcik DK, Okano H, Mitra PP.

Brain Struct Funct. 2018 Oct 4. doi: 10.1007/s00429-018-1764-4. [Epub ahead of print]


Semiquantitative Evaluation of Muscle Repair by Diffusion Tensor Imaging in Mice.

Hata J, Mizuno S, Haga Y, Shimoda M, Kanai Y, Chiba K, Okano H, Nakamura M, Horiuchi K.

JBMR Plus. 2018 Mar 5;2(4):227-234. doi: 10.1002/jbm4.10040. eCollection 2018 Jul.


Assessing cortical plasticity after spinal cord injury by using resting-state functional magnetic resonance imaging in awake adult mice.

Matsubayashi K, Nagoshi N, Komaki Y, Kojima K, Shinozaki M, Tsuji O, Iwanami A, Ishihara R, Takata N, Matsumoto M, Mimura M, Okano H, Nakamura M.

Sci Rep. 2018 Sep 26;8(1):14406. doi: 10.1038/s41598-018-32766-8.


The pathogenesis linked to coenzyme Q10 insufficiency in iPSC-derived neurons from patients with multiple-system atrophy.

Nakamoto FK, Okamoto S, Mitsui J, Sone T, Ishikawa M, Yamamoto Y, Kanegae Y, Nakatake Y, Imaizumi K, Ishiura H, Tsuji S, Okano H.

Sci Rep. 2018 Sep 21;8(1):14215. doi: 10.1038/s41598-018-32573-1.


Control of directionality of chromatin folding for the inter- and intra-domain contacts at the Tfap2c-Bmp7 locus.

Tsujimura T, Takase O, Yoshikawa M, Sano E, Hayashi M, Takato T, Toyoda A, Okano H, Hishikawa K.

Epigenetics Chromatin. 2018 Sep 14;11(1):51. doi: 10.1186/s13072-018-0221-1.


The LKB1-SIK Pathway Controls Dendrite Self-Avoidance in Purkinje Cells.

Kuwako KI, Okano H.

Cell Rep. 2018 Sep 11;24(11):2808-2818.e4. doi: 10.1016/j.celrep.2018.08.029.


Responses to pup vocalizations in subordinate naked mole-rats are induced by estradiol ingested through coprophagy of queen's feces.

Watarai A, Arai N, Miyawaki S, Okano H, Miura K, Mogi K, Kikusui T.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9264-9269. doi: 10.1073/pnas.1720530115. Epub 2018 Aug 27.


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