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Items: 8


Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile.

Wilson KJ, Xiao J, Chen CZ, Huang Z, Agoulnik IU, Ferrer M, Southall N, Hu X, Zheng W, Xu X, Wang A, Myhr C, Barnaeva E, George ER, Agoulnik AI, Marugan JJ.

Eur J Med Chem. 2018 Aug 5;156:79-92. doi: 10.1016/j.ejmech.2018.06.008. Epub 2018 Jun 7.


Human Relaxin Receptor Is Fully Functional in Humanized Mice and Is Activated by Small Molecule Agonist ML290.

Kaftanovskaya EM, Soula M, Myhr C, Ho BA, Moore SN, Yoo C, Cervantes B, How J, Marugan J, Agoulnik IU, Agoulnik AI.

J Endocr Soc. 2017 Jun;1(6):712-725. doi: 10.1210/js.2017-00112. Epub 2017 May 8.


Structural Insights into the Activation of Human Relaxin Family Peptide Receptor 1 by Small-Molecule Agonists.

Hu X, Myhr C, Huang Z, Xiao J, Barnaeva E, Ho BA, Agoulnik IU, Ferrer M, Marugan JJ, Southall N, Agoulnik AI.

Biochemistry. 2016 Mar 29;55(12):1772-83. doi: 10.1021/acs.biochem.5b01195. Epub 2016 Mar 4.


Activation of Relaxin Family Receptor 1 from Different Mammalian Species by Relaxin Peptide and Small-Molecule Agonist ML290.

Huang Z, Myhr C, Bathgate RA, Ho BA, Bueno A, Hu X, Xiao J, Southall N, Barnaeva E, Agoulnik IU, Marugan JJ, Ferrer M, Agoulnik AI.

Front Endocrinol (Lausanne). 2015 Aug 17;6:128. doi: 10.3389/fendo.2015.00128. eCollection 2015.


Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes.

Xue S, Posgai A, Wasserfall C, Myhr C, Campbell-Thompson M, Mathews CE, Brusko T, Rabinovitch A, Savinov A, Battaglia M, Schatz D, Haller M, Atkinson MA.

Diabetes. 2015 Nov;64(11):3873-84. doi: 10.2337/db15-0164. Epub 2015 Jul 16.


Genetic ablation of androgen receptor signaling in fetal Leydig cell lineage affects Leydig cell functions in adult testis.

Kaftanovskaya EM, Lopez C, Ferguson L, Myhr C, Agoulnik AI.

FASEB J. 2015 Jun;29(6):2327-37. doi: 10.1096/fj.14-263632. Epub 2015 Feb 20.


Reduced serum vitamin D-binding protein levels are associated with type 1 diabetes.

Blanton D, Han Z, Bierschenk L, Linga-Reddy MV, Wang H, Clare-Salzler M, Haller M, Schatz D, Myhr C, She JX, Wasserfall C, Atkinson M.

Diabetes. 2011 Oct;60(10):2566-70. doi: 10.2337/db11-0576. Epub 2011 Aug 15.


Community treatment orders: relationship to clinical care, medication compliance, behavioural disturbance and readmission.

Vaughan K, McConaghy N, Wolf C, Myhr C, Black T.

Aust N Z J Psychiatry. 2000 Oct;34(5):801-8.


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