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Items: 20

1.

Unique signalling connectivity of FGFR3-TACC3 oncoprotein revealed by quantitative phosphoproteomics and differential network analysis.

Lombardi B, Ashford P, Moya-Garcia AA, Rust A, Crawford M, Williams SV, Knowles MA, Katan M, Orengo C, Godovac-Zimmermann J.

Oncotarget. 2017 Oct 25;8(61):102898-102911. doi: 10.18632/oncotarget.22048. eCollection 2017 Nov 28.

2.

Exploring the interactions of the RAS family in the human protein network and their potential implications in RAS-directed therapies.

Bueno A, Morilla I, Diez D, Moya-Garcia AA, Lozano J, Ranea JA.

Oncotarget. 2016 Nov 15;7(46):75810-75826. doi: 10.18632/oncotarget.12416.

3.

Aminooxy analog of histamine is an efficient inhibitor of mammalian L-histidine decarboxylase: combined in silico and experimental evidence.

Castro-Oropeza R, Pino-Ángeles A, Khomutov MA, Urdiales JL, Moya-García AA, Vepsäläinen J, Persson L, Sarabia F, Khomutov A, Sánchez-Jiménez F.

Amino Acids. 2014 Mar;46(3):621-31. doi: 10.1007/s00726-013-1589-7. Epub 2013 Oct 10.

PMID:
24129980
4.

Insights into polypharmacology from drug-domain associations.

Moya-García AA, Ranea JA.

Bioinformatics. 2013 Aug 15;29(16):1934-7. doi: 10.1093/bioinformatics/btt321. Epub 2013 Jun 5.

PMID:
23740740
5.

Biocomputational resources useful for drug discovery against compartmentalized targets.

Sánchez-Jiménez F, Reyes-Palomares A, Moya-García AA, Ranea JA, Medina MÁ.

Curr Pharm Des. 2014;20(2):293-300. Review.

PMID:
23701544
6.

Bicyclic derivatives of L-idonojirimycin as pharmacological chaperones for neuronopathic forms of Gaucher disease.

Alfonso P, Andreu V, Pino-Angeles A, Moya-García AA, García-Moreno MI, Rodríguez-Rey JC, Sánchez-Jiménez F, Pocoví M, Ortiz Mellet C, García Fernández JM, Giraldo P.

Chembiochem. 2013 May 27;14(8):943-9. doi: 10.1002/cbic.201200708. Epub 2013 Apr 18.

PMID:
23606264
7.

Structural perspective on the direct inhibition mechanism of EGCG on mammalian histidine decarboxylase and DOPA decarboxylase.

Ruiz-Pérez MV, Pino-Ángeles A, Medina MA, Sánchez-Jiménez F, Moya-García AA.

J Chem Inf Model. 2012 Jan 23;52(1):113-9. doi: 10.1021/ci200221z. Epub 2011 Dec 15.

PMID:
22107329
8.

Analysis of Mammalian Histidine Decarboxylase Dimerization Interface Reveals an Electrostatic Hotspot Important for Catalytic Site Topology and Function.

Moya-García AA, Rodríguez-Agudo D, Hayashi H, Medina MA, Urdiales JL, Sánchez-Jiménez F.

J Chem Theory Comput. 2011 Jun 14;7(6):1935-42. doi: 10.1021/ct100690p. Epub 2011 May 13.

PMID:
26596454
9.

The function of histamine receptor H4R in the brain revealed by interaction partners.

Moya-Garcia AA, Rodriguez CE, Morilla I, Sanchez-Jimenez F, Ranea JA.

Front Biosci (Schol Ed). 2011 Jun 1;3:1058-66.

PMID:
21622255
10.

Molecular characterization of five patients with homocystinuria due to severe methylenetetrahydrofolate reductase deficiency.

Urreizti R, Moya-García AA, Pino-Ángeles A, Cozar M, Langkilde A, Fanhoe U, Esteves C, Arribas J, Vilaseca MA, Pérez-Dueñas B, Pineda M, González V, Artuch R, Baldellou A, Vilarinho L, Fowler B, Ribes A, Sánchez-Jiménez F, Grinberg D, Balcells S.

Clin Genet. 2010 Nov;78(5):441-8. doi: 10.1111/j.1399-0004.2010.01391.x.

PMID:
20236116
11.

Substrate uptake and protein stability relationship in mammalian histidine decarboxylase.

Pino-Angeles A, Morreale A, Negri A, Sánchez-Jiménez F, Moya-García AA.

Proteins. 2010 Jan;78(1):154-61. doi: 10.1002/prot.22587.

PMID:
19790266
12.

Structural features of mammalian histidine decarboxylase reveal the basis for specific inhibition.

Moya-García AA, Pino-Angeles A, Gil-Redondo R, Morreale A, Sánchez-Jiménez F.

Br J Pharmacol. 2009 May;157(1):4-13. doi: 10.1111/j.1476-5381.2009.00219.x. Review.

13.

Molecular modeling and site-directed mutagenesis reveal essential residues for catalysis in a prokaryote-type aspartate aminotransferase.

de la Torre F, Moya-García AA, Suárez MF, Rodríguez-Caso C, Cañas RA, Sánchez-Jiménez F, Cánovas FM.

Plant Physiol. 2009 Apr;149(4):1648-60. doi: 10.1104/pp.108.134510. Epub 2009 Jan 28.

14.

AMMO-Prot: amine system project 3D-model finder.

Navas-Delgado I, Montañez R, Pino-Angeles A, Moya-García AA, Urdiales JL, Sánchez-Jiménez F, Aldana-Montes JF.

BMC Bioinformatics. 2008 Apr 25;9 Suppl 4:S5. doi: 10.1186/1471-2105-9-S4-S5.

15.

Analysis of the decarboxylation step in mammalian histidine decarboxylase. A computational study.

Moya-García AA, Ruiz-Pernía J, Martí S, Sánchez-Jiménez F, Tuñón I.

J Biol Chem. 2008 May 2;283(18):12393-401. doi: 10.1074/jbc.M707434200. Epub 2008 Feb 29.

16.

Study by optical spectroscopy and molecular dynamics of the interaction of acridine-spermine conjugate with DNA.

Sánchez-Carrasco S, Delcros JG, Moya-García AA, Sánchez-Jiménez F, Ramírez FJ.

Biophys Chem. 2008 Mar;133(1-3):54-65. doi: 10.1016/j.bpc.2007.12.003. Epub 2007 Dec 23.

PMID:
18191014
17.
18.

Mammalian histidine decarboxylase: from structure to function.

Moya-Garcia AA, Medina MA, Sánchez-Jiménez F.

Bioessays. 2005 Jan;27(1):57-63. Review.

PMID:
15612036
19.

Mapping of catalytically important residues in the rat L-histidine decarboxylase enzyme using bioinformatic and site-directed mutagenesis approaches.

Fleming JV, Sánchez-Jiménez F, Moya-García AA, Langlois MR, Wang TC.

Biochem J. 2004 Apr 15;379(Pt 2):253-61.

20.

Local changes in the catalytic site of mammalian histidine decarboxylase can affect its global conformation and stability.

Rodríguez-Caso C, Rodríguez-Agudo D, Moya-García AA, Fajardo I, Medina MA, Subramaniam V, Sánchez-Jiménez F.

Eur J Biochem. 2003 Nov;270(21):4376-87.

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