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Items: 1 to 20 of 148

1.

Liver Progenitors and Adult Cell Plasticity in Hepatic Injury and Repair: Knowns and Unknowns.

Ko S, Russell JO, Molina LM, Monga SP.

Annu Rev Pathol. 2019 Aug 9. doi: 10.1146/annurev-pathmechdis-012419-032824. [Epub ahead of print]

PMID:
31399003
2.

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.

Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, Fondevilla C, Stärkel P, Dubuquoy L, Louvet A, Odena G, Gomez JL, Aragon T, Altamirano J, Caballeria J, Jurczak MJ, Taylor DL, Berasain C, Wahlestedt C, Monga SP, Morgan MY, Sancho-Bru P, Mathurin P, Furuya S, Lackner C, Rusyn I, Shah VH, Thursz MR, Mann J, Avila MA, Bataller R.

Nat Commun. 2019 Jul 16;10(1):3126. doi: 10.1038/s41467-019-11004-3.

3.

β-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma.

Ruiz de Galarreta M, Bresnahan E, Molina-Sánchez P, Lindblad KE, Maier B, Sia D, Puigvehi M, Miguela V, Casanova-Acebes M, Dhainaut M, Villacorta-Martin C, Singhi AD, Moghe A, von Felden J, Tal Grinspan L, Wang S, Kamphorst AO, Monga SP, Brown BD, Villanueva A, Llovet JM, Merad M, Lujambio A.

Cancer Discov. 2019 Aug;9(8):1124-1141. doi: 10.1158/2159-8290.CD-19-0074. Epub 2019 Jun 11.

PMID:
31186238
4.

Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice.

Yan J, Tung HC, Li S, Niu Y, Garbacz WG, Lu P, Bi Y, Li Y, He J, Xu M, Ren S, Monga SP, Schwabe RF, Yang D, Xie W.

Gastroenterology. 2019 Jun 3. pii: S0016-5085(19)40984-0. doi: 10.1053/j.gastro.2019.05.066. [Epub ahead of print]

PMID:
31170413
5.

Impaired Ribosomal Biogenesis by Noncanonical Degradation of β-Catenin during Hyperammonemia.

Davuluri G, Giusto M, Chandel R, Welch N, Alsabbagh K, Kant S, Kumar A, Kim A, Gangadhariah M, Ghosh PK, Tran U, Krajcik DM, Vasu K, DiDonato AJ, DiDonato JA, Willard B, Monga SP, Wang Y, Fox PL, Stark GR, Wessely O, Esser KA, Dasarathy S.

Mol Cell Biol. 2019 Jul 29;39(16). pii: e00451-18. doi: 10.1128/MCB.00451-18. Print 2019 Aug 15.

PMID:
31138664
6.

Notch Inhibition Promotes Differentiation of Liver Progenitor Cells into Hepatocytes via sox9b Repression in Zebrafish.

Russell JO, Ko S, Monga SP, Shin D.

Stem Cells Int. 2019 Mar 12;2019:8451282. doi: 10.1155/2019/8451282. eCollection 2019.

7.

Reply.

Chen X, Monga SP, Calvisi DF.

Hepatology. 2019 Aug;70(2):764-765. doi: 10.1002/hep.30644. No abstract available.

PMID:
30958900
8.

Dynamics and predicted drug response of a gene network linking dedifferentiation with beta-catenin dysfunction in hepatocellular carcinoma.

Gérard C, Di-Luoffo M, Gonay L, Caruso S, Couchy G, Loriot A, Castven D, Tao J, Konobrocka K, Cordi S, Monga SP, Hanert E, Marquardt JU, Zucman-Rossi J, Lemaigre FP.

J Hepatol. 2019 Aug;71(2):323-332. doi: 10.1016/j.jhep.2019.03.024. Epub 2019 Apr 4.

PMID:
30953666
9.

mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development.

Molina L, Yang H, Adebayo Michael AO, Oertel M, Bell A, Singh S, Chen X, Tao J, Monga SPS.

Oncotarget. 2019 Feb 19;10(15):1475-1490. doi: 10.18632/oncotarget.26668. eCollection 2019 Feb 19.

10.

β-Catenin and Yes-Associated Protein 1 Cooperate in Hepatoblastoma Pathogenesis.

Min Q, Molina L, Li J, Adebayo Michael AO, Russell JO, Preziosi ME, Singh S, Poddar M, Matz-Soja M, Ranganathan S, Bell AW, Gebhardt R, Gaunitz F, Yu J, Tao J, Monga SP.

Am J Pathol. 2019 May;189(5):1091-1104. doi: 10.1016/j.ajpath.2019.02.002. Epub 2019 Feb 19. Erratum in: Am J Pathol. 2019 Aug;189(8):1680.

PMID:
30794807
11.

TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma.

Zhang J, Liu P, Tao J, Wang P, Zhang Y, Song X, Che L, Sumazin P, Ribback S, Kiss A, Schaff Z, Cigliano A, Dombrowski F, Cossu C, Pascale RM, Calvisi DF, Monga SP, Chen X.

Am J Pathol. 2019 May;189(5):1077-1090. doi: 10.1016/j.ajpath.2019.01.016. Epub 2019 Feb 19.

PMID:
30794805
12.

Axis inhibition protein 1 (Axin1) Deletion-Induced Hepatocarcinogenesis Requires Intact β-Catenin but Not Notch Cascade in Mice.

Qiao Y, Wang J, Karagoz E, Liang B, Song X, Shang R, Evert K, Xu M, Che L, Evert M, Calvisi DF, Tao J, Wang B, Monga SP, Chen X.

Hepatology. 2019 Feb 8. doi: 10.1002/hep.30556. [Epub ahead of print]

PMID:
30737831
13.

Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.

Adebayo Michael AO, Ko S, Tao J, Moghe A, Yang H, Xu M, Russell JO, Pradhan-Sundd T, Liu S, Singh S, Poddar M, Monga JS, Liu P, Oertel M, Ranganathan S, Singhi A, Rebouissou S, Zucman-Rossi J, Ribback S, Calvisi D, Qvartskhava N, Görg B, Häussinger D, Chen X, Monga SP.

Cell Metab. 2019 May 7;29(5):1135-1150.e6. doi: 10.1016/j.cmet.2019.01.002. Epub 2019 Jan 31.

PMID:
30713111
14.

Blood-Bile Barrier: Morphology, Regulation, and Pathophysiology.

Pradhan-Sundd T, Monga SP.

Gene Expr. 2019 Apr 18;19(2):69-87. doi: 10.3727/105221619X15469715711907. Epub 2019 Jan 15.

15.

Loss of Wnt Secretion by Macrophages Promotes Hepatobiliary Injury after Administration of 3,5-Diethoxycarbonyl-1, 4-Dihydrocollidine Diet.

Jiang A, Okabe H, Popovic B, Preziosi ME, Pradhan-Sundd T, Poddar M, Singh S, Bell A, England SG, Nagarajan S, Monga SP.

Am J Pathol. 2019 Mar;189(3):590-603. doi: 10.1016/j.ajpath.2018.11.010. Epub 2019 Jan 2.

16.

Updates on hepatic homeostasis and the many tiers of hepatobiliary repair.

Monga SP.

Nat Rev Gastroenterol Hepatol. 2019 Feb;16(2):84-86. doi: 10.1038/s41575-018-0090-x. Review. No abstract available.

PMID:
30531815
17.

Oncogenic potential of N-terminal deletion and S45Y mutant β-catenin in promoting hepatocellular carcinoma development in mice.

Qiao Y, Xu M, Tao J, Che L, Cigliano A, Monga SP, Calvisi DF, Chen X.

BMC Cancer. 2018 Nov 12;18(1):1093. doi: 10.1186/s12885-018-4870-z.

18.

Loss of hepatocyte β-catenin protects mice from experimental porphyria-associated liver injury.

Saggi H, Maitra D, Jiang A, Zhang R, Wang P, Cornuet P, Singh S, Locker J, Ma X, Dailey H, Abrams M, Omary MB, Monga SP, Nejak-Bowen K.

J Hepatol. 2019 Jan;70(1):108-117. doi: 10.1016/j.jhep.2018.09.023. Epub 2018 Oct 1.

PMID:
30287339
19.

Hdac1 Regulates Differentiation of Bipotent Liver Progenitor Cells During Regeneration via Sox9b and Cdk8.

Ko S, Russell JO, Tian J, Gao C, Kobayashi M, Feng R, Yuan X, Shao C, Ding H, Poddar M, Singh S, Locker J, Weng HL, Monga SP, Shin D.

Gastroenterology. 2019 Jan;156(1):187-202.e14. doi: 10.1053/j.gastro.2018.09.039. Epub 2018 Sep 26.

PMID:
30267710
20.

Elimination of Wnt Secretion From Stellate Cells Is Dispensable for Zonation and Development of Liver Fibrosis Following Hepatobiliary Injury.

Zhang R, Kikuchi AT, Nakao T, Russell JO, Preziosi ME, Poddar M, Singh S, Bell AW, England SG, Monga SP.

Gene Expr. 2019 Apr 18;19(2):121-136. doi: 10.3727/105221618X15373858350141. Epub 2018 Sep 20.

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