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Items: 1 to 20 of 394

1.

Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart.

Correll RN, Grimes KM, Prasad V, Lynch JM, Khalil H, Molkentin JD.

Sci Rep. 2019 Feb 14;9(1):2059. doi: 10.1038/s41598-019-39515-5.

2.

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

Schips TG, Vanhoutte D, Vo A, Correll RN, Brody MJ, Khalil H, Karch J, Tjondrokoesoemo A, Sargent MA, Maillet M, Ross RS, Molkentin JD.

Nat Commun. 2019 Jan 8;10(1):76. doi: 10.1038/s41467-018-08026-8.

3.

Cardiac-specific deficiency of the mitochondrial calcium uniporter augments fatty acid oxidation and functional reserve.

Altamimi TR, Karwi QG, Uddin GM, Fukushima A, Kwong JQ, Molkentin JD, Lopaschuk GD.

J Mol Cell Cardiol. 2019 Feb;127:223-231. doi: 10.1016/j.yjmcc.2018.12.019. Epub 2019 Jan 4.

PMID:
30615880
4.

Myofibroblast-Specific TGFβ Receptor II Signaling in the Fibrotic Response to Cardiac Myosin Binding Protein C-Induced Cardiomyopathy.

Meng Q, Bhandary B, Bhuiyan MS, James J, Osinska H, Valiente-Alandi I, Shay-Winkler K, Gulick J, Molkentin JD, Blaxall BC, Robbins J.

Circ Res. 2018 Dec 7;123(12):1285-1297. doi: 10.1161/CIRCRESAHA.118.313089.

PMID:
30566042
5.

Evidence for Minimal Cardiogenic Potential of Stem Cell Antigen 1-Positive Cells in the Adult Mouse Heart.

Neidig LE, Weinberger F, Palpant NJ, Mignone J, Martinson AM, Sorensen DW, Bender I, Nemoto N, Reinecke H, Pabon L, Molkentin JD, Murry CE, van Berlo JH.

Circulation. 2018 Dec 18;138(25):2960-2962. doi: 10.1161/CIRCULATIONAHA.118.035273. No abstract available.

6.

The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle.

Kwong JQ, Huo J, Bround MJ, Boyer JG, Schwanekamp JA, Ghazal N, Maxwell JT, Jang YC, Khuchua Z, Shi K, Bers DM, Davis J, Molkentin JD.

JCI Insight. 2018 Nov 15;3(22). pii: 121689. doi: 10.1172/jci.insight.121689.

7.

Cardiac Fibrosis in Proteotoxic Cardiac Disease is Dependent Upon Myofibroblast TGF -β Signaling.

Bhandary B, Meng Q, James J, Osinska H, Gulick J, Valiente-Alandi I, Sargent MA, Bhuiyan MS, Blaxall BC, Molkentin JD, Robbins J.

J Am Heart Assoc. 2018 Oct 16;7(20):e010013. doi: 10.1161/JAHA.118.010013.

8.

Undeniable Evidence That the Adult Mammalian Heart Lacks an Endogenous Regenerative Stem Cell.

Maliken BD, Molkentin JD.

Circulation. 2018 Aug 21;138(8):806-808. doi: 10.1161/CIRCULATIONAHA.118.035186. No abstract available.

PMID:
30359129
9.

Nuclear calcineurin is a sensor for detecting Ca2+ release from the nuclear envelope via IP3R.

Olivares-Florez S, Czolbe M, Riediger F, Seidlmayer L, Williams T, Nordbeck P, Strasen J, Glocker C, Jänsch M, Eder-Negrin P, Arias-Loza P, Mühlfelder M, Plačkić J, Heinze KG, Molkentin JD, Engelhardt S, Kockskämper J, Ritter O.

J Mol Med (Berl). 2018 Nov;96(11):1239-1249. doi: 10.1007/s00109-018-1701-2. Epub 2018 Oct 6.

PMID:
30293136
10.

Author Correction: Yolk sac macrophage progenitors traffic to the embryo during defined stages of development.

Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, Mass E, Ishikawa-Ankerhold HC, Margraf A, Hutter S, Vagnozzi R, Klapproth S, Frampton J, Yona S, Scheiermann C, Molkentin JD, Jeschke U, Moser M, Sperandio M, Massberg S, Geissmann F, Schulz C.

Nat Commun. 2018 Sep 7;9(1):3699. doi: 10.1038/s41467-018-06065-9.

11.

Protein Kinase C Inhibition With Ruboxistaurin Increases Contractility and Reduces Heart Size in a Swine Model of Heart Failure With Reduced Ejection Fraction.

Sharp TE 3rd, Kubo H, Berretta RM, Starosta T, Wallner M, Schena GJ, Hobby AR, Yu D, Trappanese DM, George JC, Molkentin JD, Houser SR.

JACC Basic Transl Sci. 2017 Dec 25;2(6):669-683. doi: 10.1016/j.jacbts.2017.06.007. eCollection 2017 Dec.

12.

Genetic Lineage Tracing of Sca-1+ Cells Reveals Endothelial but Not Myogenic Contribution to the Murine Heart.

Vagnozzi RJ, Sargent MA, Lin SJ, Palpant NJ, Murry CE, Molkentin JD.

Circulation. 2018 Dec 18;138(25):2931-2939. doi: 10.1161/CIRCULATIONAHA.118.035210.

PMID:
29991486
13.

New Myocyte Formation in the Adult Heart: Endogenous Sources and Therapeutic Implications.

Vagnozzi RJ, Molkentin JD, Houser SR.

Circ Res. 2018 Jul 6;123(2):159-176. doi: 10.1161/CIRCRESAHA.118.311208.

PMID:
29976685
14.

Developmental vascular regression is regulated by a Wnt/β-catenin, MYC and CDKN1A pathway that controls cell proliferation and cell death.

Nayak G, Odaka Y, Prasad V, Solano AF, Yeo EJ, Vemaraju S, Molkentin JD, Trumpp A, Williams B, Rao S, Lang RA.

Development. 2018 Jun 14;145(12). pii: dev154898. doi: 10.1242/dev.154898.

15.

Defective Flux of Thrombospondin-4 through the Secretory Pathway Impairs Cardiomyocyte Membrane Stability and Causes Cardiomyopathy.

Brody MJ, Vanhoutte D, Schips TG, Boyer JG, Bakshi CV, Sargent MA, York AJ, Molkentin JD.

Mol Cell Biol. 2018 Apr 30. pii: MCB.00114-18. doi: 10.1128/MCB.00114-18. [Epub ahead of print]

16.

Gata4-Dependent Differentiation of c-Kit+-Derived Endothelial Cells Underlies Artefactual Cardiomyocyte Regeneration in the Heart.

Maliken BD, Kanisicak O, Karch J, Khalil H, Fu X, Boyer JG, Prasad V, Zheng Y, Molkentin JD.

Circulation. 2018 Sep 4;138(10):1012-1024. doi: 10.1161/CIRCULATIONAHA.118.033703.

17.

Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart.

Fu X, Khalil H, Kanisicak O, Boyer JG, Vagnozzi RJ, Maliken BD, Sargent MA, Prasad V, Valiente-Alandi I, Blaxall BC, Molkentin JD.

J Clin Invest. 2018 May 1;128(5):2127-2143. doi: 10.1172/JCI98215. Epub 2018 Apr 16.

18.

Inhibiting Fibronectin Attenuates Fibrosis and Improves Cardiac Function in a Model of Heart Failure.

Valiente-Alandi I, Potter SJ, Salvador AM, Schafer AE, Schips T, Carrillo-Salinas F, Gibson AM, Nieman ML, Perkins C, Sargent MA, Huo J, Lorenz JN, DeFalco T, Molkentin JD, Alcaide P, Blaxall BC.

Circulation. 2018 Sep 18;138(12):1236-1252. doi: 10.1161/CIRCULATIONAHA.118.034609.

PMID:
29653926
19.

van Berlo et al. reply.

van Berlo JH, Kanisicak O, Maillet M, Vagnozzi RJ, Karch J, Lin SJ, Middleton RC, Marbán E, Molkentin JD.

Nature. 2018 Mar 21;555(7697):E18. doi: 10.1038/nature25772. No abstract available.

PMID:
29565361
20.

Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects.

Hu R, Morley MP, Brandimarto J, Tucker NR, Parsons VA, Zhao SD, Meder B, Katus HA, Rühle F, Stoll M, Villard E, Cambien F, Lin H, Smith NL, Felix JF, Vasan RS, van der Harst P, Newton-Cheh C, Li J, Kim CE, Hakonarson H, Hannenhalli S, Ashley EA, Moravec CS, Tang WHW, Maillet M, Molkentin JD, Ellinor PT, Margulies KB, Cappola TP.

Circ Genom Precis Med. 2018 Mar;11(3):e001901. doi: 10.1161/CIRCGEN.117.001901.

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