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Items: 1 to 20 of 34

1.

A two-stage approach to the joint analysis of longitudinal and survival data utilising the Coxian phase-type distribution.

Donnelly C, McFetridge LM, Marshall AH, Mitchell HJ.

Stat Methods Med Res. 2017 Jan 1:962280217706727. doi: 10.1177/0962280217706727. [Epub ahead of print]

PMID:
28633604
2.

The preclinical efficacy, selectivity and pharmacologic profile of MK-5932, an insulin-sparing selective glucocorticoid receptor modulator.

Brandish PE, Anderson K, Baltus GA, Bai C, Bungard CJ, Bunting P, Byford A, Chiu CS, Cicmil M, Corcoran H, Euler D, Fisher JE, Gambone C, Hasbun-Manning M, Kuklin N, Landis E, Lifsted TQ, McElwee-Witmer S, McIntosh IS, Meissner RS, Miao J, Mitchell HJ, Musselman A, Schmidt A, Shin J, Szczerba P, Thompson CD, Tribouley C, Vogel RL, Warrier S, Hershey JC.

Eur J Pharmacol. 2014 Feb 5;724:102-11. doi: 10.1016/j.ejphar.2013.12.031. Epub 2013 Dec 27.

PMID:
24374007
3.

Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiology.

Schmidt A, Kimmel DB, Bai C, Scafonas A, Rutledge S, Vogel RL, McElwee-Witmer S, Chen F, Nantermet PV, Kasparcova V, Leu CT, Zhang HZ, Duggan ME, Gentile MA, Hodor P, Pennypacker B, Masarachia P, Opas EE, Adamski SA, Cusick TE, Wang J, Mitchell HJ, Kim Y, Prueksaritanont T, Perkins JJ, Meissner RS, Hartman GD, Freedman LP, Harada S, Ray WJ.

J Biol Chem. 2010 May 28;285(22):17054-64. doi: 10.1074/jbc.M109.099002. Epub 2010 Mar 31.

4.

Interleukin-1beta-induced brain injury in the neonatal rat can be ameliorated by alpha-phenyl-n-tert-butyl-nitrone.

Fan LW, Mitchell HJ, Tien LT, Rhodes PG, Cai Z.

Exp Neurol. 2009 Nov;220(1):143-53. doi: 10.1016/j.expneurol.2009.08.003. Epub 2009 Aug 13.

5.

Design, synthesis, and biological evaluation of 16-substituted 4-azasteroids as tissue-selective androgen receptor modulators (SARMs).

Mitchell HJ, Dankulich WP, Hartman GD, Prueksaritanont T, Schmidt A, Vogel RL, Bai C, McElwee-Witmer S, Zhang HZ, Chen F, Leu CT, Kimmel DB, Ray WJ, Nantermet P, Gentile MA, Duggan ME, Meissner RS.

J Med Chem. 2009 Aug 13;52(15):4578-81. doi: 10.1021/jm900880r.

PMID:
19606870
6.

alpha-Phenyl-n-tert-butyl-nitrone attenuates lipopolysaccharide-induced brain injury and improves neurological reflexes and early sensorimotor behavioral performance in juvenile rats.

Fan LW, Chen RF, Mitchell HJ, Lin RC, Simpson KL, Rhodes PG, Cai Z.

J Neurosci Res. 2008 Dec;86(16):3536-47. doi: 10.1002/jnr.21812.

7.

Alpha-phenyl-n-tert-butyl-nitrone ameliorates hippocampal injury and improves learning and memory in juvenile rats following neonatal exposure to lipopolysaccharide.

Fan LW, Tien LT, Mitchell HJ, Rhodes PG, Cai Z.

Eur J Neurosci. 2008 Mar;27(6):1475-84. doi: 10.1111/j.1460-9568.2008.06121.x.

PMID:
18364024
8.

Alpha-Phenyl-n-tert-butyl-nitrone attenuates lipopolysaccharide-induced neuronal injury in the neonatal rat brain.

Fan LW, Mitchell HJ, Rhodes PG, Cai Z.

Neuroscience. 2008 Feb 6;151(3):737-44. doi: 10.1016/j.neuroscience.2007.09.087. Epub 2007 Nov 29.

9.

alpha-Phenyl-n-tert-butyl-nitrone reduces lipopolysaccharide-induced white matter injury in the neonatal rat brain.

Fan LW, Mitchell HJ, Tien LT, Zheng B, Pang Y, Rhodes PG, Cai Z.

Dev Neurobiol. 2008 Feb 15;68(3):365-78.

10.

Characterisation of manganese superoxide dismutase from Phytophthora nicotianae.

Blackman LM, Mitchell HJ, Hardham AR.

Mycol Res. 2005 Oct;109(Pt 10):1171-83.

PMID:
16279411
11.

IGF-1 protects oligodendrocyte progenitor cells and improves neurological functions following cerebral hypoxia-ischemia in the neonatal rat.

Lin S, Fan LW, Pang Y, Rhodes PG, Mitchell HJ, Cai Z.

Brain Res. 2005 Nov 23;1063(1):15-26. Epub 2005 Nov 2.

PMID:
16259966
12.

Comparative analysis in cereals of a key proline catabolism gene.

Ayliffe MA, Mitchell HJ, Deuschle K, Pryor AJ.

Mol Genet Genomics. 2005 Dec;274(5):494-505. Epub 2005 Sep 23.

PMID:
16179990
13.

A rust-inducible gene from flax (fis1) is involved in proline catabolism.

Mitchell HJ, Ayliffe MA, Rashid KY, Pryor AJ.

Planta. 2006 Jan;223(2):213-22. Epub 2005 Aug 4.

PMID:
16079997
14.

Gene transfer to plants by diverse species of bacteria.

Broothaerts W, Mitchell HJ, Weir B, Kaines S, Smith LM, Yang W, Mayer JE, Roa-Rodríguez C, Jefferson RA.

Nature. 2005 Feb 10;433(7026):629-33.

PMID:
15703747
15.

Total synthesis of apoptolidin: completion of the synthesis and analogue synthesis and evaluation.

Nicolaou KC, Li Y, Sugita K, Monenschein H, Guntupalli P, Mitchell HJ, Fylaktakidou KC, Vourloumis D, Giannakakou P, O'Brate A.

J Am Chem Soc. 2003 Dec 17;125(50):15443-54.

PMID:
14664590
16.

Total synthesis of apoptolidin: construction of enantiomerically pure fragments.

Nicolaou KC, Fylaktakidou KC, Monenschein H, Li Y, Weyershausen B, Mitchell HJ, Wei HX, Guntupalli P, Hepworth D, Sugita K.

J Am Chem Soc. 2003 Dec 17;125(50):15433-42.

PMID:
14664589
17.

A plant gene up-regulated at rust infection sites.

Ayliffe MA, Roberts JK, Mitchell HJ, Zhang R, Lawrence GJ, Ellis JG, Pryor TJ.

Plant Physiol. 2002 May;129(1):169-80.

20.

Total Synthesis of Apoptolidin: Part 2. Coupling of Key Building Blocks and Completion of the Synthesis.

Nicolaou KC, Li Y, Fylaktakidou KC, Mitchell HJ, Sugita K.

Angew Chem Int Ed Engl. 2001 Oct 15;40(20):3854-3857. doi: 10.1002/1521-3773(20011015)40:20<3854::AID-ANIE3854>3.0.CO;2-D.

PMID:
29712136

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