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Items: 1 to 20 of 25

2.

The Binding of Silibinin, the Main Constituent of Silymarin, to Site I on Human Serum Albumin.

Yamasaki K, Sato H, Minagoshi S, Kyubun K, Anraku M, Miyamura S, Watanabe H, Taguchi K, Seo H, Maruyama T, Otagiri M.

Biol Pharm Bull. 2017;40(3):310-317. doi: 10.1248/bpb.b16-00790.

3.

Effects of Silymarin, Glycyrrhizin, and Oxymatrine on the Pharmacokinetics of Ribavirin and Its Major Metabolite in Rats.

Liao S, Jin X, Li J, Zhang T, Zhang W, Shi W, Fan S, Wang X, Wang J, Zhong B, Zhang Z.

Phytother Res. 2016 Apr;30(4):618-26. doi: 10.1002/ptr.5567. Epub 2016 Jan 22.

PMID:
26800424
4.

Pharmacokinetic Interactions between Drugs and Botanical Dietary Supplements.

Sprouse AA, van Breemen RB.

Drug Metab Dispos. 2016 Feb;44(2):162-71. doi: 10.1124/dmd.115.066902. Epub 2015 Oct 5. Review.

5.

An ex vivo approach to botanical-drug interactions: a proof of concept study.

Wang X, Zhu HJ, Munoz J, Gurley BJ, Markowitz JS.

J Ethnopharmacol. 2015 Apr 2;163:149-56. doi: 10.1016/j.jep.2015.01.021. Epub 2015 Jan 24.

6.

The effects of milk thistle (Silybum marianum) on human cytochrome P450 activity.

Kawaguchi-Suzuki M, Frye RF, Zhu HJ, Brinda BJ, Chavin KD, Bernstein HJ, Markowitz JS.

Drug Metab Dispos. 2014 Oct;42(10):1611-6. doi: 10.1124/dmd.114.057232. Epub 2014 Jul 15.

7.

The in-vitro effect of complementary and alternative medicines on cytochrome P450 2C9 activity.

Mooiman KD, Goey AK, Huijbregts TJ, Maas-Bakker RF, Beijnen JH, Schellens JH, Meijerman I.

J Pharm Pharmacol. 2014 Sep;66(9):1339-46. doi: 10.1111/jphp.12259. Epub 2014 Apr 15.

PMID:
24730468
8.

Herb-drug interactions: challenges and opportunities for improved predictions.

Brantley SJ, Argikar AA, Lin YS, Nagar S, Paine MF.

Drug Metab Dispos. 2014 Mar;42(3):301-17. doi: 10.1124/dmd.113.055236. Epub 2013 Dec 11.

9.

A systematic approach to evaluate herb-drug interaction mechanisms: investigation of milk thistle extracts and eight isolated constituents as CYP3A inhibitors.

Brantley SJ, Graf TN, Oberlies NH, Paine MF.

Drug Metab Dispos. 2013 Sep;41(9):1662-70. doi: 10.1124/dmd.113.052563. Epub 2013 Jun 25.

10.

Relevance of in vitro and clinical data for predicting CYP3A4-mediated herb-drug interactions in cancer patients.

Goey AK, Mooiman KD, Beijnen JH, Schellens JH, Meijerman I.

Cancer Treat Rev. 2013 Nov;39(7):773-83. doi: 10.1016/j.ctrv.2012.12.008. Epub 2013 Feb 8. Review.

PMID:
23394826
11.

Clinical evidence of herbal drugs as perpetrators of pharmacokinetic drug interactions.

Hermann R, von Richter O.

Planta Med. 2012 Sep;78(13):1458-77. doi: 10.1055/s-0032-1315117. Epub 2012 Aug 1. Review.

12.

[Pharmacokinetic drug interactions by herbal drugs: Critical evaluation and clinical relevance].

Unger M.

Wien Med Wochenschr. 2010 Dec;160(21-22):571-7. doi: 10.1007/s10354-010-0848-4. Review. German.

PMID:
21170698
13.

Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities.

Doehmer J, Weiss G, McGregor GP, Appel K.

Toxicol In Vitro. 2011 Feb;25(1):21-7. doi: 10.1016/j.tiv.2010.09.001. Epub 2010 Sep 7.

PMID:
20828605
14.
15.

Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations.

Brantley SJ, Oberlies NH, Kroll DJ, Paine MF.

J Pharmacol Exp Ther. 2010 Mar;332(3):1081-7. doi: 10.1124/jpet.109.161927. Epub 2009 Nov 24.

16.

Herb-drug interaction of silymarin or silibinin on the pharmacokinetics of trazodone in rats.

Chang JC, Wu YT, Lee WC, Lin LC, Tsai TH.

Chem Biol Interact. 2009 Dec 10;182(2-3):227-32. doi: 10.1016/j.cbi.2009.09.005. Epub 2009 Sep 16.

PMID:
19765569
17.

What's in a name?

Bell W.

Can Fam Physician. 2008 Feb;54(2):183, 185. No abstract available.

18.

Exacerbation of hemochromatosis by ingestion of milk thistle.

Kidd R.

Can Fam Physician. 2008 Feb;54(2):182; author reply 182-3. No abstract available.

19.

Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea.

Gurley BJ, Swain A, Hubbard MA, Williams DK, Barone G, Hartsfield F, Tong Y, Carrier DJ, Cheboyina S, Battu SK.

Mol Nutr Food Res. 2008 Jul;52(7):755-63. doi: 10.1002/mnfr.200600300.

20.

The effect of silymarin on oral nifedipine pharmacokinetics.

Fuhr U, Beckmann-Knopp S, Jetter A, Lück H, Mengs U.

Planta Med. 2007 Nov;73(14):1429-35. Epub 2007 Oct 30.

PMID:
17968815

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