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Items: 1 to 20 of 103

1.

Multivariate techniques enable a biochemical classification of children with autism spectrum disorder versus typically-developing peers: A comparison and validation study.

Howsmon DP, Vargason T, Rubin RA, Delhey L, Tippett M, Rose S, Bennuri SC, Slattery JC, Melnyk S, James SJ, Frye RE, Hahn J.

Bioeng Transl Med. 2018 Jun 19;3(2):156-165. doi: 10.1002/btm2.10095. eCollection 2018 May.

2.

Early Ambulation in Patients With External Ventricular Drains: Results of a Quality Improvement Project.

Shah SO, Kraft J, Ankam N, Bu P, Stout K, Melnyk S, Rincon F, Athar MK.

J Intensive Care Med. 2018 Jun;33(6):370-374. doi: 10.1177/0885066616677507. Epub 2016 Nov 10.

PMID:
29747562
3.

Comparison of Treatment for Metabolic Disorders Associated with Autism:Reanalysis of Three Clinical Trials.

Delhey LM, Tippett M, Rose S, Bennuri SC, Slattery JC, Melnyk S, James SJ, Frye RE.

Front Neurosci. 2018 Feb 12;12:19. doi: 10.3389/fnins.2018.00019. eCollection 2018.

4.

Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism.

Rose S, Bennuri SC, Davis JE, Wynne R, Slattery JC, Tippett M, Delhey L, Melnyk S, Kahler SG, MacFabe DF, Frye RE.

Transl Psychiatry. 2018 Feb 2;8(1):42. doi: 10.1038/s41398-017-0089-z.

5.

Epigenetically mediated inhibition of S-adenosylhomocysteine hydrolase and the associated dysregulation of 1-carbon metabolism in nonalcoholic steatohepatitis and hepatocellular carcinoma.

Pogribny IP, Dreval K, Kindrat I, Melnyk S, Jimenez L, de Conti A, Tryndyak V, Pogribna M, Ortega JF, James SJ, Rusyn I, Beland FA.

FASEB J. 2018 Mar;32(3):1591-1601. doi: 10.1096/fj.201700866R. Epub 2018 Jan 3.

PMID:
29127188
6.

Autistic Siblings with Novel Mutations in Two Different Genes: Insight for Genetic Workups of Autistic Siblings and Connection to Mitochondrial Dysfunction.

Burger BJ, Rose S, Bennuri SC, Gill PS, Tippett ML, Delhey L, Melnyk S, Frye RE.

Front Pediatr. 2017 Oct 12;5:219. doi: 10.3389/fped.2017.00219. eCollection 2017.

7.

Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology.

Miousse IR, Pathak R, Garg S, Skinner CM, Melnyk S, Pavliv O, Hendrickson H, Landes RD, Lumen A, Tackett AJ, Deutz NEP, Hauer-Jensen M, Koturbash I.

Genes Nutr. 2017 Sep 6;12:22. doi: 10.1186/s12263-017-0576-0. eCollection 2017.

8.

Chemo brain or tumor brain - that is the question: the presence of extracranial tumors profoundly affects molecular processes in the prefrontal cortex of TumorGraft mice.

Kovalchuk A, Ilnytskyy Y, Rodriguez-Juarez R, Shpyleva S, Melnyk S, Pogribny I, Katz A, Sidransky D, Kovalchuk O, Kolb B.

Aging (Albany NY). 2017 Jul 29;9(7):1660-1676. doi: 10.18632/aging.101243.

9.

Effects of low-dose rate γ-irradiation combined with simulated microgravity on markers of oxidative stress, DNA methylation potential, and remodeling in the mouse heart.

Seawright JW, Samman Y, Sridharan V, Mao XW, Cao M, Singh P, Melnyk S, Koturbash I, Nelson GA, Hauer-Jensen M, Boerma M.

PLoS One. 2017 Jul 5;12(7):e0180594. doi: 10.1371/journal.pone.0180594. eCollection 2017.

10.

Effects of Obesity on Pro-Oxidative Conditions and DNA Damage in Liver of DMBA-Induced Mammary Carcinogenesis Models.

Melnyk S, Korourian S, Levy JW, Pavliv O, Evans T, Hakkak R.

Metabolites. 2017 Jun 8;7(2). pii: E26. doi: 10.3390/metabo7020026.

11.

One-carbon metabolism and ionizing radiation: a multifaceted interaction.

Miousse IR, Tobacyk J, Melnyk S, James SJ, Cheema AK, Boerma M, Hauer-Jensen M, Koturbash I.

Biomol Concepts. 2017 May 24;8(2):83-92. doi: 10.1515/bmc-2017-0003. Review.

PMID:
28574375
12.

Classification and adaptive behavior prediction of children with autism spectrum disorder based upon multivariate data analysis of markers of oxidative stress and DNA methylation.

Howsmon DP, Kruger U, Melnyk S, James SJ, Hahn J.

PLoS Comput Biol. 2017 Mar 16;13(3):e1005385. doi: 10.1371/journal.pcbi.1005385. eCollection 2017 Mar.

13.

Overexpression of LINE-1 Retrotransposons in Autism Brain.

Shpyleva S, Melnyk S, Pavliv O, Pogribny I, Jill James S.

Mol Neurobiol. 2018 Feb;55(2):1740-1749. doi: 10.1007/s12035-017-0421-x. Epub 2017 Feb 20.

PMID:
28220356
14.

Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder.

Frye RE, Wynne R, Rose S, Slattery J, Delhey L, Tippett M, Kahler SG, Bennuri SC, Melnyk S, Sequeira JM, Quadros EV.

J Neuroendocrinol. 2017 Mar;29(3). doi: 10.1111/jne.12461.

PMID:
28199771
15.

Mathematical modeling of the methionine cycle and transsulfuration pathway in individuals with autism spectrum disorder.

Vargason T, Howsmon DP, Melnyk S, James SJ, Hahn J.

J Theor Biol. 2017 Mar 7;416:28-37. doi: 10.1016/j.jtbi.2016.12.021. Epub 2016 Dec 29.

16.

Editor's Highlight: Organ-Specific Epigenetic Changes Induced by the Nongenotoxic Liver Carcinogen Methapyrilene in Fischer 344 Rats.

Shpyleva S, Dreval K, de Conti A, Kindrat I, Melnyk S, Yan J, Chen T, Beland FA, Pogribny IP.

Toxicol Sci. 2017 Mar 1;156(1):190-198. doi: 10.1093/toxsci/kfw242.

PMID:
28013212
17.

Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study.

Rose S, Bennuri SC, Wynne R, Melnyk S, James SJ, Frye RE.

FASEB J. 2017 Mar;31(3):904-909. doi: 10.1096/fj.201601004R. Epub 2016 Nov 18.

18.

Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines.

Frye RE, Rose S, Chacko J, Wynne R, Bennuri SC, Slattery JC, Tippett M, Delhey L, Melnyk S, Kahler SG, MacFabe DF.

Transl Psychiatry. 2016 Oct 25;6(10):e927. doi: 10.1038/tp.2016.189.

19.

Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial.

Frye RE, Slattery J, Delhey L, Furgerson B, Strickland T, Tippett M, Sailey A, Wynne R, Rose S, Melnyk S, Jill James S, Sequeira JM, Quadros EV.

Mol Psychiatry. 2018 Feb;23(2):247-256. doi: 10.1038/mp.2016.168. Epub 2016 Oct 18.

20.

Sex-specific effects of cytotoxic chemotherapy agents cyclophosphamide and mitomycin C on gene expression, oxidative DNA damage, and epigenetic alterations in the prefrontal cortex and hippocampus - an aging connection.

Kovalchuk A, Rodriguez-Juarez R, Ilnytskyy Y, Byeon B, Shpyleva S, Melnyk S, Pogribny I, Kolb B, Kovalchuk O.

Aging (Albany NY). 2016 Apr;8(4):697-711. doi: 10.18632/aging.100920.

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