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Items: 1 to 20 of 87

1.

IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer.

Zhang Y, Wester L, He J, Geiger T, Moerkens M, Siddappa R, Helmijr JA, Timmermans MM, Look MP, van Deurzen CHM, Martens JWM, Pont C, de Graauw M, Danen EHJ, Berns EMJJ, Meerman JHN, Jansen MPHM, van de Water B.

Oncogene. 2018 Apr;37(14):1869-1884. doi: 10.1038/s41388-017-0027-9. Epub 2018 Jan 22.

PMID:
29353882
2.

Ultra high content image analysis and phenotype profiling of 3D cultured micro-tissues.

Di Z, Klop MJ, Rogkoti VM, Le Dévédec SE, van de Water B, Verbeek FJ, Price LS, Meerman JH.

PLoS One. 2014 Oct 7;9(10):e109688. doi: 10.1371/journal.pone.0109688. eCollection 2014.

3.
4.

β1 integrin inhibition elicits a prometastatic switch through the TGFβ-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer.

Truong HH, Xiong J, Ghotra VP, Nirmala E, Haazen L, Le Dévédec SE, Balcioğlu HE, He S, Snaar-Jagalska BE, Vreugdenhil E, Meerman JH, van de Water B, Danen EH.

Sci Signal. 2014 Feb 11;7(312):ra15. doi: 10.1126/scisignal.2004751.

PMID:
24518294
5.

Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells.

Carreras Puigvert J, von Stechow L, Siddappa R, Pines A, Bahjat M, Haazen LC, Olsen JV, Vrieling H, Meerman JH, Mullenders LH, van de Water B, Danen EH.

Sci Signal. 2013 Jan 22;6(259):ra5. doi: 10.1126/scisignal.2003208.

PMID:
23354688
6.

Automated analysis of NF-κB nuclear translocation kinetics in high-throughput screening.

Di Z, Herpers B, Fredriksson L, Yan K, van de Water B, Verbeek FJ, Meerman JH.

PLoS One. 2012;7(12):e52337. doi: 10.1371/journal.pone.0052337. Epub 2012 Dec 27.

7.

Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a noninvasive biomarker of oxidative stress.

European Standards Committee on Urinary (DNA) Lesion Analysis, Evans MD, Olinski R, Loft S, Cooke MS.

FASEB J. 2010 Apr;24(4):1249-60. doi: 10.1096/fj.09-147124. Epub 2009 Dec 4.

8.

Temporal and functional dynamics of the transcriptome during nerve growth factor-induced differentiation.

Dijkmans TF, van Hooijdonk LW, Schouten TG, Kamphorst JT, Vellinga AC, Meerman JH, Fitzsimons CP, de Kloet ER, Vreugdenhil E.

J Neurochem. 2008 Jun 1;105(6):2388-403. doi: 10.1111/j.1471-4159.2008.05338.x.

9.

Metabolic profiling of endocrine-disrupting compounds by on-line cytochrome p450 bioreaction coupled to on-line receptor affinity screening.

Van Liempd SM, Kool J, Meerman JH, Irth H, Vermeulen NP.

Chem Res Toxicol. 2007 Dec;20(12):1825-32. Epub 2007 Nov 1.

PMID:
17975887
10.

Online biochemical detection of glutathione-S-transferase P1-specific inhibitors in complex mixtures.

Kool J, Eggink M, van Rossum H, van Liempd SM, van Elswijk DA, Irth H, Commandeur JN, Meerman JH, Vermeulen NP.

J Biomol Screen. 2007 Apr;12(3):396-405. Epub 2007 Mar 22.

PMID:
17379858
11.

Screening the oxidative potential of several mono- and di-halogenated biphenyls and biphenyl ethers in rat hepatocytes.

Gurer-Orhan H, Orhan H, Vermeulen NP, Meerman JH.

Comb Chem High Throughput Screen. 2006 Jul;9(6):449-54.

PMID:
16842226
12.

Rapid on-line profiling of estrogen receptor binding metabolites of tamoxifen.

Kool J, Ramautar R, van Liempd SM, Beckman J, de Kanter FJ, Meerman JH, Schenk T, Irth H, Commandeur JN, Vermeulen NP.

J Med Chem. 2006 Jun 1;49(11):3287-92.

PMID:
16722647
13.

Application of lipid peroxidation and protein oxidation biomarkers for oxidative damage in mammalian cells. A comparison with two fluorescent probes.

Orhan H, Gurer-Orhan H, Vriese E, Vermeulen NP, Meerman JH.

Toxicol In Vitro. 2006 Sep;20(6):1005-13. Epub 2006 Feb 20.

PMID:
16488111
14.

Bioactivation of dibrominated biphenyls by cytochrome P450 activity to metabolites with estrogenic activity and estrogen sulfotransferase inhibition capacity.

van Lipzig MM, Commandeur JN, de Kanter FJ, Damsten MC, Vermeulen NP, Maat E, Groot EJ, Brouwer A, Kester MH, Visser TJ, Meerman JH.

Chem Res Toxicol. 2005 Nov;18(11):1691-700.

PMID:
16300378
15.

The chemical interaction between the estrogen receptor and monohydroxybenzo[a]pyrene derivatives studied by fluorescence line-narrowing spectroscopy.

Bader AN, van Dongen MM, van Lipzig MM, Kool J, Meerman JH, Ariese F, Gooijer C.

Chem Res Toxicol. 2005 Sep;18(9):1405-12.

PMID:
16167832
16.

Development of a novel cytochrome p450 bioaffinity detection system coupled online to gradient reversed-phase high-performance liquid chromatography.

Kool J, van Liempd SM, Ramautar R, Schenk T, Meerman JH, Irth H, Commandeur JN, Vermeulen NP.

J Biomol Screen. 2005 Aug;10(5):427-36.

PMID:
16093552
17.

Development and validation of a microsomal online cytochrome P450 bioreactor coupled to solid-phase extraction and reversed-phase liquid chromatography.

van Liempd SM, Kool J, Reinen J, Schenk T, Meerman JH, Irth H, Vermeulen NP.

J Chromatogr A. 2005 May 20;1075(1-2):205-12.

PMID:
15974134
19.

Evaluation of a multi-parameter biomarker set for oxidative damage in man: increased urinary excretion of lipid, protein and DNA oxidation products after one hour of exercise.

Orhan H, van Holland B, Krab B, Moeken J, Vermeulen NP, Hollander P, Meerman JH.

Free Radic Res. 2004 Dec;38(12):1269-79.

PMID:
15763951
20.

Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity.

van Lipzig MM, Vermeulen NP, Gusinu R, Legler J, Frank H, Seidel A, Meerman JH.

Environ Toxicol Pharmacol. 2005 Jan;19(1):41-55. doi: 10.1016/j.etap.2004.03.010.

PMID:
21783461

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