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Items: 1 to 20 of 41

1.

Microbiological and cellular evaluation of fluorine-phosphorus doped titanium alloy: A novel antibacterial and osteostimulatory biomaterial with potential applications in orthopedic surgery.

Aguilera-Correa JJ, Mediero A, Conesa-Buendía FM, Conde A, Arenas MÁ, de-Damborenea JJ, Esteban J.

Appl Environ Microbiol. 2018 Oct 26. pii: AEM.02271-18. doi: 10.1128/AEM.02271-18. [Epub ahead of print]

PMID:
30367003
2.

Local delivery of adenosine receptor agonists to promote bone regeneration and defect healing.

Lopez CD, Bekisz JM, Corciulo C, Mediero A, Coelho PG, Witek L, Flores RL, Cronstein BN.

Adv Drug Deliv Rev. 2018 Jun 18. pii: S0169-409X(18)30149-2. doi: 10.1016/j.addr.2018.06.010. [Epub ahead of print]

PMID:
29913176
3.

Validation of Musculoskeletal Ultrasound in the Assessment of Experimental Gout Synovitis.

Naredo E, Medina JP, Pérez-Baos S, Mediero A, Herrero-Beaumont G, Largo R.

Ultrasound Med Biol. 2018 Jul;44(7):1516-1524. doi: 10.1016/j.ultrasmedbio.2018.03.018. Epub 2018 Apr 24.

PMID:
29703511
4.

The Role of Adenosine Receptor Activation in Attenuating Cartilaginous Inflammation.

Bekisz JM, Lopez CD, Corciulo C, Mediero A, Coelho PG, Witek L, Flores RL, Cronstein BN.

Inflammation. 2018 Aug;41(4):1135-1141. doi: 10.1007/s10753-018-0781-z. Review.

PMID:
29656316
5.

Adenosine A2A receptor (A2AR) stimulation modulates expression of semaphorins 4D and 3A, regulators of bone homeostasis.

Mediero A, Wilder T, Shah L, Cronstein BN.

FASEB J. 2018 Jul;32(7):3487-3501. doi: 10.1096/fj.201700217R. Epub 2018 Feb 2.

PMID:
29394106
6.

The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin.

Feig JL, Mediero A, Corciulo C, Liu H, Zhang J, Perez-Aso M, Picard L, Wilder T, Cronstein B.

PLoS One. 2017 Nov 16;12(11):e0188135. doi: 10.1371/journal.pone.0188135. eCollection 2017.

7.

Unexpected Bone Formation Produced by RANKL Blockade.

Portal-Núñez S, Mediero A, Esbrit P, Sánchez-Pernaute O, Largo R, Herrero-Beaumont G.

Trends Endocrinol Metab. 2017 Oct;28(10):695-704. doi: 10.1016/j.tem.2017.06.003. Epub 2017 Jul 19. Review.

PMID:
28733136
8.

The combined therapy with chondroitin sulfate plus glucosamine sulfate or chondroitin sulfate plus glucosamine hydrochloride does not improve joint damage in an experimental model of knee osteoarthritis in rabbits.

Roman-Blas JA, Mediero A, Tardío L, Portal-Nuñez S, Gratal P, Herrero-Beaumont G, Largo R.

Eur J Pharmacol. 2017 Jan 5;794:8-14. doi: 10.1016/j.ejphar.2016.11.015. Epub 2016 Nov 12.

PMID:
27845067
9.

Ticagrelor regulates osteoblast and osteoclast function and promotes bone formation in vivo via an adenosine-dependent mechanism.

Mediero A, Wilder T, Reddy VS, Cheng Q, Tovar N, Coelho PG, Witek L, Whatling C, Cronstein BN.

FASEB J. 2016 Nov;30(11):3887-3900. Epub 2016 Aug 10.

10.

Netrin-1 and its receptor Unc5b are novel targets for the treatment of inflammatory arthritis.

Mediero A, Wilder T, Ramkhelawon B, Moore KJ, Cronstein BN.

FASEB J. 2016 Nov;30(11):3835-3844. Epub 2016 Aug 8.

11.

Adenosine A2A receptor promotes collagen type III synthesis via β-catenin activation in human dermal fibroblasts.

Shaikh G, Zhang J, Perez-Aso M, Mediero A, Cronstein B.

Br J Pharmacol. 2016 Dec;173(23):3279-3291. doi: 10.1111/bph.13615. Epub 2016 Oct 4.

12.

Bone regeneration in critical bone defects using three-dimensionally printed β-tricalcium phosphate/hydroxyapatite scaffolds is enhanced by coating scaffolds with either dipyridamole or BMP-2.

Ishack S, Mediero A, Wilder T, Ricci JL, Cronstein BN.

J Biomed Mater Res B Appl Biomater. 2017 Feb;105(2):366-375. doi: 10.1002/jbm.b.33561. Epub 2015 Oct 29.

13.

Netrin-1 is highly expressed and required in inflammatory infiltrates in wear particle-induced osteolysis.

Mediero A, Ramkhelawon B, Wilder T, Purdue PE, Goldring SR, Dewan MZ, Loomis C, Moore KJ, Cronstein BN.

Ann Rheum Dis. 2016 Sep;75(9):1706-13. doi: 10.1136/annrheumdis-2015-207593. Epub 2015 Oct 9.

14.

Adenosine A2A receptor plays an important role in radiation-induced dermal injury.

Perez-Aso M, Mediero A, Low YC, Levine J, Cronstein BN.

FASEB J. 2016 Jan;30(1):457-65. doi: 10.1096/fj.15-280388. Epub 2015 Sep 28.

15.

Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors.

Perez-Aso M, Montesinos MC, Mediero A, Wilder T, Schafer PH, Cronstein B.

Arthritis Res Ther. 2015 Sep 15;17:249. doi: 10.1186/s13075-015-0771-6.

16.

Direct or indirect stimulation of adenosine A2A receptors enhances bone regeneration as well as bone morphogenetic protein-2.

Mediero A, Wilder T, Perez-Aso M, Cronstein BN.

FASEB J. 2015 Apr;29(4):1577-90. doi: 10.1096/fj.14-265066. Epub 2015 Jan 8.

17.

Brief Report: Methotrexate Prevents Wear Particle-Induced Inflammatory Osteolysis in Mice Via Activation of Adenosine A2A Receptor.

Mediero A, Perez-Aso M, Wilder T, Cronstein BN.

Arthritis Rheumatol. 2015 Mar;67(3):849-55. doi: 10.1002/art.38971.

18.

Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiation.

Mediero A, Ramkhelawon B, Perez-Aso M, Moore KJ, Cronstein BN.

J Bone Miner Res. 2015 May;30(5):837-54. doi: 10.1002/jbmr.2421.

19.

Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements.

Mediero A, Perez-Aso M, Cronstein BN.

FASEB J. 2014 Nov;28(11):4901-13. doi: 10.1096/fj.14-255703. Epub 2014 Aug 13.

20.

Effect of melatonin and analogues on corneal wound healing: involvement of Mt2 melatonin receptor.

Crooke A, Guzman-Aranguez A, Mediero A, Alarma-Estrany P, Carracedo G, Pelaez T, Peral A, Pintor J.

Curr Eye Res. 2015 Jan;40(1):56-65. doi: 10.3109/02713683.2014.914540. Epub 2014 Jun 3.

PMID:
24892818

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