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Items: 1 to 20 of 30

1.

Brain Nat8l Knockdown Suppresses Spongiform Leukodystrophy in an Aspartoacylase-Deficient Canavan Disease Mouse Model.

Bannerman P, Guo F, Chechneva O, Burns T, Zhu X, Wang Y, Kim B, Singhal NK, McDonough JA, Pleasure D.

Mol Ther. 2018 Mar 7;26(3):793-800. doi: 10.1016/j.ymthe.2018.01.002. Epub 2018 Jan 10.

PMID:
29456021
2.

Liquid crystal elastomer foams with elastic properties specifically engineered as biodegradable brain tissue scaffolds.

Prévôt ME, Andro H, Alexander SLM, Ustunel S, Zhu C, Nikolov Z, Rafferty ST, Brannum MT, Kinsel B, Korley LTJ, Freeman EJ, McDonough JA, Clements RJ, Hegmann E.

Soft Matter. 2018 Jan 17;14(3):354-360. doi: 10.1039/c7sm01949a.

PMID:
29236117
3.

The ω-3 fatty acid α-linolenic acid extends Caenorhabditis elegans lifespan via NHR-49/PPARα and oxidation to oxylipins.

Qi W, Gutierrez GE, Gao X, Dixon H, McDonough JA, Marini AM, Fisher AL.

Aging Cell. 2017 Oct;16(5):1125-1135. doi: 10.1111/acel.12651. Epub 2017 Aug 3.

4.

Suppressing N-Acetyl-l-Aspartate Synthesis Prevents Loss of Neurons in a Murine Model of Canavan Leukodystrophy.

Sohn J, Bannerman P, Guo F, Burns T, Miers L, Croteau C, Singhal NK, McDonough JA, Pleasure D.

J Neurosci. 2017 Jan 11;37(2):413-421. doi: 10.1523/JNEUROSCI.2013-16.2016.

5.

Effects of Structural Variations on the Cellular Response and Mechanical Properties of Biocompatible, Biodegradable, and Porous Smectic Liquid Crystal Elastomers.

Sharma A, Mori T, Mahnen CJ, Everson HR, Leslie MT, Nielsen AD, Lussier L, Zhu C, Malcuit C, Hegmann T, McDonough JA, Freeman EJ, Korley LT, Clements RJ, Hegmann E.

Macromol Biosci. 2017 Feb;17(2). doi: 10.1002/mabi.201600278. Epub 2016 Nov 2.

PMID:
27805765
6.

Circulatory Failure During Noninhaled Forms of Cyanide Intoxication.

Haouzi P, Tubbs N, Rannals MD, Judenherc-Haouzi A, Cabell LA, McDonough JA, Sonobe T.

Shock. 2017 Mar;47(3):352-362. doi: 10.1097/SHK.0000000000000732.

7.

Liquid Crystal Elastomer Microspheres as Three-Dimensional Cell Scaffolds Supporting the Attachment and Proliferation of Myoblasts.

Bera T, Freeman EJ, McDonough JA, Clements RJ, Aladlaan A, Miller DW, Malcuit C, Hegmann T, Hegmann E.

ACS Appl Mater Interfaces. 2015 Jul 8;7(26):14528-35. doi: 10.1021/acsami.5b04208. Epub 2015 Jun 25.

PMID:
26075811
8.

Ablating N-acetylaspartate prevents leukodystrophy in a Canavan disease model.

Guo F, Bannerman P, Mills Ko E, Miers L, Xu J, Burns T, Li S, Freeman E, McDonough JA, Pleasure D.

Ann Neurol. 2015 May;77(5):884-8. doi: 10.1002/ana.24392. Epub 2015 Mar 27.

PMID:
25712859
9.

Biocompatible, biodegradable and porous liquid crystal elastomer scaffolds for spatial cell cultures.

Sharma A, Neshat A, Mahnen CJ, Nielsen AD, Snyder J, Stankovich TL, Daum BG, LaSpina EM, Beltrano G, Gao Y, Li S, Park BW, Clements RJ, Freeman EJ, Malcuit C, McDonough JA, Korley LT, Hegmann T, Hegmann E.

Macromol Biosci. 2015 Feb;15(2):200-14. doi: 10.1002/mabi.201400325. Epub 2014 Oct 10.

PMID:
25303674
10.

A screen of Coxiella burnetii mutants reveals important roles for Dot/Icm effectors and host autophagy in vacuole biogenesis.

Newton HJ, Kohler LJ, McDonough JA, Temoche-Diaz M, Crabill E, Hartland EL, Roy CR.

PLoS Pathog. 2014 Jul 31;10(7):e1004286. doi: 10.1371/journal.ppat.1004286. eCollection 2014 Jul.

11.

International Journal of Toxicology special edition volume of MMB4 DMS.

Burback BL, Cabell LA, Johnson JD, McDonough JA, Osheroff MR.

Int J Toxicol. 2013 Jul-Aug;32(4 Suppl):3S-4S. doi: 10.1177/1091581813487854. No abstract available.

PMID:
23929449
12.

Good manufacturing practice: manufacturing of a nerve agent antidote nanoparticle suspension.

Clark AP, Dixon H, Cantu NL, Cabell LA, McDonough JA.

Int J Toxicol. 2013 Jul-Aug;32(4 Suppl):5S-17S. doi: 10.1177/1091581813490204.

PMID:
23929446
13.

MMB4 DMS nanoparticle suspension formulation with enhanced stability for the treatment of nerve agent intoxication.

Dixon H, Clark AP, Cabell LA, McDonough JA.

Int J Toxicol. 2013 Jul-Aug;32(4 Suppl):18S-29S. doi: 10.1177/1091581813489314.

PMID:
23929445
14.

Host pathways important for Coxiella burnetii infection revealed by genome-wide RNA interference screening.

McDonough JA, Newton HJ, Klum S, Swiss R, Agaisse H, Roy CR.

MBio. 2013 Jan 29;4(1):e00606-12. doi: 10.1128/mBio.00606-12.

15.

Effector protein translocation by the Coxiella burnetii Dot/Icm type IV secretion system requires endocytic maturation of the pathogen-occupied vacuole.

Newton HJ, McDonough JA, Roy CR.

PLoS One. 2013;8(1):e54566. doi: 10.1371/journal.pone.0054566. Epub 2013 Jan 17.

16.

The role of Rab GTPases in the transport of vacuoles containing Legionella pneumophila and Coxiella burnetii.

Hardiman CA, McDonough JA, Newton HJ, Roy CR.

Biochem Soc Trans. 2012 Dec 1;40(6):1353-9. doi: 10.1042/BST20120167. Review.

PMID:
23176480
17.

Coxiella burnetii secretion systems.

McDonough JA, Newton HJ, Roy CR.

Adv Exp Med Biol. 2012;984:171-97. doi: 10.1007/978-94-007-4315-1_9. Review.

PMID:
22711632
18.

Genome-wide identification of Mycobacterium tuberculosis exported proteins with roles in intracellular growth.

McCann JR, McDonough JA, Sullivan JT, Feltcher ME, Braunstein M.

J Bacteriol. 2011 Feb;193(4):854-61. doi: 10.1128/JB.01271-10. Epub 2010 Dec 10.

19.

The Anaplasma phagocytophilum-occupied vacuole selectively recruits Rab-GTPases that are predominantly associated with recycling endosomes.

Huang B, Hubber A, McDonough JA, Roy CR, Scidmore MA, Carlyon JA.

Cell Microbiol. 2010 Sep 1;12(9):1292-307. doi: 10.1111/j.1462-5822.2010.01468.x. Epub 2010 Mar 25.

20.

The Accessory SecA2 System of Mycobacteria Requires ATP Binding and the Canonical SecA1.

Rigel NW, Gibbons HS, McCann JR, McDonough JA, Kurtz S, Braunstein M.

J Biol Chem. 2009 Apr 10;284(15):9927-36. doi: 10.1074/jbc.M900325200. Epub 2009 Feb 23.

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