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Items: 1 to 20 of 131


Fibroblast growth factor 21 and fructose dynamics in humans.

Migdal A, Comte S, Rodgers M, Heineman B, Maratos-Flier E, Herman M, Dushay J.

Obes Sci Pract. 2018 Sep 4;4(5):483-489. doi: 10.1002/osp4.295. eCollection 2018 Oct. Erratum in: Obes Sci Pract. 2019 Feb 19;5(1):91. Flier, E M [corrected to Maratos-Flier, E].


Deficiency of fibroblast growth factor 21 (FGF21) promotes hepatocellular carcinoma (HCC) in mice on a long term obesogenic diet.

Singhal G, Kumar G, Chan S, Fisher FM, Ma Y, Vardeh HG, Nasser IA, Flier JS, Maratos-Flier E.

Mol Metab. 2018 Jul;13:56-66. doi: 10.1016/j.molmet.2018.03.002. Epub 2018 Mar 8.


The FGF21 response to fructose predicts metabolic health and persists after bariatric surgery in obese humans.

Ter Horst KW, Gilijamse PW, Demirkiran A, van Wagensveld BA, Ackermans MT, Verheij J, Romijn JA, Nieuwdorp M, Maratos-Flier E, Herman MA, Serlie MJ.

Mol Metab. 2017 Nov;6(11):1493-1502. doi: 10.1016/j.molmet.2017.08.014. Epub 2017 Sep 4.


Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury.

Desai BN, Singhal G, Watanabe M, Stevanovic D, Lundasen T, Fisher FM, Mather ML, Vardeh HG, Douris N, Adams AC, Nasser IA, FitzGerald GA, Flier JS, Skarke C, Maratos-Flier E.

Mol Metab. 2017 Nov;6(11):1395-1406. doi: 10.1016/j.molmet.2017.08.004. Epub 2017 Aug 19.


Beta-adrenergic receptors are critical for weight loss but not for other metabolic adaptations to the consumption of a ketogenic diet in male mice.

Douris N, Desai BN, Fisher FM, Cisu T, Fowler AJ, Zarebidaki E, Nguyen NLT, Morgan DA, Bartness TJ, Rahmouni K, Flier JS, Maratos-Flier E.

Mol Metab. 2017 Jun 6;6(8):854-862. doi: 10.1016/j.molmet.2017.05.017. eCollection 2017 Aug.


Leptin's Physiologic Role: Does the Emperor of Energy Balance Have No Clothes?

Flier JS, Maratos-Flier E.

Cell Metab. 2017 Jul 5;26(1):24-26. doi: 10.1016/j.cmet.2017.05.013. Epub 2017 Jun 22.


Fatty liver and FGF21 physiology.

Maratos-Flier E.

Exp Cell Res. 2017 Nov 1;360(1):2-5. doi: 10.1016/j.yexcr.2017.05.006. Epub 2017 May 23. Review.


A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism.

Fisher FM, Kim M, Doridot L, Cunniff JC, Parker TS, Levine DM, Hellerstein MK, Hudgins LC, Maratos-Flier E, Herman MA.

Mol Metab. 2016 Nov 23;6(1):14-21. doi: 10.1016/j.molmet.2016.11.008. eCollection 2017 Jan.


Elevated Serum Fibroblast Growth Factor 21 in Humans with Acute Pancreatitis.

Shenoy VK, Beaver KM, Fisher FM, Singhal G, Dushay JR, Maratos-Flier E, Flier SN.

PLoS One. 2016 Nov 10;11(11):e0164351. doi: 10.1371/journal.pone.0164351. eCollection 2016.


Fibroblast growth factor 21 has no direct role in regulating fertility in female mice.

Singhal G, Douris N, Fish AJ, Zhang X, Adams AC, Flier JS, Pissios P, Maratos-Flier E.

Mol Metab. 2016 May 18;5(8):690-698. doi: 10.1016/j.molmet.2016.05.010. eCollection 2016 Aug.


iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy.

Lynch L, Hogan AE, Duquette D, Lester C, Banks A, LeClair K, Cohen DE, Ghosh A, Lu B, Corrigan M, Stevanovic D, Maratos-Flier E, Drucker DJ, O'Shea D, Brenner M.

Cell Metab. 2016 Sep 13;24(3):510-519. doi: 10.1016/j.cmet.2016.08.003. Epub 2016 Sep 1.


Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas.

Singhal G, Fisher FM, Chee MJ, Tan TG, El Ouaamari A, Adams AC, Najarian R, Kulkarni RN, Benoist C, Flier JS, Maratos-Flier E.

PLoS One. 2016 Feb 12;11(2):e0148252. doi: 10.1371/journal.pone.0148252. eCollection 2016.


Understanding the Physiology of FGF21.

Fisher FM, Maratos-Flier E.

Annu Rev Physiol. 2016;78:223-41. doi: 10.1146/annurev-physiol-021115-105339. Epub 2015 Nov 19. Review.


Fibroblast growth factors in cardiovascular disease: The emerging role of FGF21.

Domouzoglou EM, Naka KK, Vlahos AP, Papafaklis MI, Michalis LK, Tsatsoulis A, Maratos-Flier E.

Am J Physiol Heart Circ Physiol. 2015 Sep 15;309(6):H1029-38. doi: 10.1152/ajpheart.00527.2015. Epub 2015 Jul 31. Review.


Adaptive changes in amino acid metabolism permit normal longevity in mice consuming a low-carbohydrate ketogenic diet.

Douris N, Melman T, Pecherer JM, Pissios P, Flier JS, Cantley LC, Locasale JW, Maratos-Flier E.

Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2056-65. doi: 10.1016/j.bbadis.2015.07.009. Epub 2015 Jul 11.


Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization.

Hong S, Moreno-Navarrete JM, Wei X, Kikukawa Y, Tzameli I, Prasad D, Lee Y, Asara JM, Fernandez-Real JM, Maratos-Flier E, Pissios P.

Nat Med. 2015 Aug;21(8):887-94. doi: 10.1038/nm.3882. Epub 2015 Jul 13.


Melanin-concentrating hormone is necessary for olanzapine-inhibited locomotor activity in male mice.

Chee MJ, Douris N, Forrow AB, Monnard A, Lu S, Flaherty SE 3rd, Adams AC, Maratos-Flier E.

Eur Neuropsychopharmacol. 2015 Oct;25(10):1808-16. doi: 10.1016/j.euroneuro.2015.05.010. Epub 2015 Jun 3.


The promyelocytic leukemia protein is upregulated in conditions of obesity and liver steatosis.

Carracedo A, Rousseau D, Douris N, Fernández-Ruiz S, Martín-Martín N, Weiss D, Webster K, Adams AC, Vazquez-Chantada M, Martinez-Chantar ML, Anty R, Tran A, Maratos-Flier E, Gual P, Pandolfi PP.

Int J Biol Sci. 2015 Apr 11;11(6):629-32. doi: 10.7150/ijbs.11615. eCollection 2015. No abstract available.


Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice.

Douris N, Stevanovic DM, Fisher FM, Cisu TI, Chee MJ, Nguyen NL, Zarebidaki E, Adams AC, Kharitonenkov A, Flier JS, Bartness TJ, Maratos-Flier E.

Endocrinology. 2015 Jul;156(7):2470-81. doi: 10.1210/en.2014-2001. Epub 2015 Apr 29.


Melanin-concentrating hormone neurons release glutamate for feedforward inhibition of the lateral septum.

Chee MJ, Arrigoni E, Maratos-Flier E.

J Neurosci. 2015 Feb 25;35(8):3644-51. doi: 10.1523/JNEUROSCI.4187-14.2015.

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