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Items: 1 to 20 of 38

1.

Notch and interacting signalling pathways in cardiac development, disease, and regeneration.

MacGrogan D, Münch J, de la Pompa JL.

Nat Rev Cardiol. 2018 Nov;15(11):685-704. doi: 10.1038/s41569-018-0100-2. Review.

PMID:
30287945
2.

A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice.

Eley L, Alqahtani AM, MacGrogan D, Richardson RV, Murphy L, Salguero-Jimenez A, Sintes Rodriguez San Pedro M, Tiurma S, McCutcheon L, Gilmore A, de La Pompa JL, Chaudhry B, Henderson DJ.

Elife. 2018 Jun 29;7. pii: e34110. doi: 10.7554/eLife.34110.

3.

Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis.

Nus M, Martínez-Poveda B, MacGrogan D, Chevre R, D'Amato G, Sbroggio M, Rodríguez C, Martínez-González J, Andrés V, Hidalgo A, de la Pompa JL.

Cardiovasc Res. 2016 Nov 1;112(2):568-580. doi: 10.1093/cvr/cvw193.

PMID:
27496872
4.

Sequential Ligand-Dependent Notch Signaling Activation Regulates Valve Primordium Formation and Morphogenesis.

MacGrogan D, D'Amato G, Travisano S, Martinez-Poveda B, Luxán G, Del Monte-Nieto G, Papoutsi T, Sbroggio M, Bou V, Gomez-Del Arco P, Gómez MJ, Zhou B, Redondo JM, Jiménez-Borreguero LJ, de la Pompa JL.

Circ Res. 2016 May 13;118(10):1480-97. doi: 10.1161/CIRCRESAHA.115.308077. Epub 2016 Apr 7.

PMID:
27056911
5.

Endocardial Notch Signaling in Cardiac Development and Disease.

Luxán G, D'Amato G, MacGrogan D, de la Pompa JL.

Circ Res. 2016 Jan 8;118(1):e1-e18. doi: 10.1161/CIRCRESAHA.115.305350. Epub 2015 Dec 3. Review.

PMID:
26635389
6.

How to make a heart valve: from embryonic development to bioengineering of living valve substitutes.

MacGrogan D, Luxán G, Driessen-Mol A, Bouten C, Baaijens F, de la Pompa JL.

Cold Spring Harb Perspect Med. 2014 Nov 3;4(11):a013912. doi: 10.1101/cshperspect.a013912. Review.

7.

Genetic and functional genomics approaches targeting the Notch pathway in cardiac development and congenital heart disease.

MacGrogan D, Luxán G, de la Pompa JL.

Brief Funct Genomics. 2014 Jan;13(1):15-27. doi: 10.1093/bfgp/elt036. Epub 2013 Oct 7. Review.

PMID:
24106100
8.

Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy.

Luxán G, Casanova JC, Martínez-Poveda B, Prados B, D'Amato G, MacGrogan D, Gonzalez-Rajal A, Dobarro D, Torroja C, Martinez F, Izquierdo-García JL, Fernández-Friera L, Sabater-Molina M, Kong YY, Pizarro G, Ibañez B, Medrano C, García-Pavía P, Gimeno JR, Monserrat L, Jiménez-Borreguero LJ, de la Pompa JL.

Nat Med. 2013 Feb;19(2):193-201. doi: 10.1038/nm.3046. Epub 2013 Jan 13.

PMID:
23314057
9.

Notch signaling in cardiac valve development and disease.

MacGrogan D, Luna-Zurita L, de la Pompa JL.

Birth Defects Res A Clin Mol Teratol. 2011 Jun;91(6):449-59. doi: 10.1002/bdra.20815. Epub 2011 May 11. Review.

PMID:
21563298
10.

Diet-induced aortic valve disease in mice haploinsufficient for the Notch pathway effector RBPJK/CSL.

Nus M, MacGrogan D, Martínez-Poveda B, Benito Y, Casanova JC, Fernández-Avilés F, Bermejo J, de la Pompa JL.

Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1580-8. doi: 10.1161/ATVBAHA.111.227561. Epub 2011 Apr 14.

PMID:
21493891
11.

Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.

del Monte G, Casanova JC, Guadix JA, MacGrogan D, Burch JB, Pérez-Pomares JM, de la Pompa JL.

Circ Res. 2011 Apr 1;108(7):824-36. doi: 10.1161/CIRCRESAHA.110.229062. Epub 2011 Feb 10.

PMID:
21311046
12.

Notch signaling in cardiac development and disease.

MacGrogan D, Nus M, de la Pompa JL.

Curr Top Dev Biol. 2010;92:333-65. doi: 10.1016/S0070-2153(10)92011-5. Review.

PMID:
20816401
13.

Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1.

Kalakonda N, Fischle W, Boccuni P, Gurvich N, Hoya-Arias R, Zhao X, Miyata Y, Macgrogan D, Zhang J, Sims JK, Rice JC, Nimer SD.

Oncogene. 2008 Jul 17;27(31):4293-304. doi: 10.1038/onc.2008.67. Epub 2008 Apr 14.

14.

Caloric intake and Alzheimer's disease. Experimental approaches and therapeutic implications.

Pasinetti GM, Zhao Z, Qin W, Ho L, Shrishailam Y, Macgrogan D, Ressmann W, Humala N, Liu X, Romero C, Stetka B, Chen L, Ksiezak-Reding H, Wang J.

Interdiscip Top Gerontol. 2007;35:159-75. Review.

PMID:
17063038
15.

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction.

Qin W, Yang T, Ho L, Zhao Z, Wang J, Chen L, Zhao W, Thiyagarajan M, MacGrogan D, Rodgers JT, Puigserver P, Sadoshima J, Deng H, Pedrini S, Gandy S, Sauve AA, Pasinetti GM.

J Biol Chem. 2006 Aug 4;281(31):21745-54. Epub 2006 Jun 2.

16.

A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis.

Zhao Z, Lange DJ, Voustianiouk A, MacGrogan D, Ho L, Suh J, Humala N, Thiyagarajan M, Wang J, Pasinetti GM.

BMC Neurosci. 2006 Apr 3;7:29.

17.

Structural integrity and expression of the L3MBTL gene in normal and malignant hematopoietic cells.

MacGrogan D, Kalakonda N, Alvarez S, Scandura JM, Boccuni P, Johansson B, Nimer SD.

Genes Chromosomes Cancer. 2004 Nov;41(3):203-13.

PMID:
15334543
18.

Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets.

Wang WK, Tereshko V, Boccuni P, MacGrogan D, Nimer SD, Patel DJ.

Structure. 2003 Jul;11(7):775-89.

19.

De novo erythroleukemia chromosome features include multiple rearrangements, with special involvement of chromosomes 11 and 19.

Cigudosa JC, Odero MD, Calasanz MJ, Solé F, Salido M, Arranz E, Martínez-Ramirez A, Urioste M, Alvarez S, Cervera JV, MacGrogan D, Sanz MA, Nimer SD, Benitez J.

Genes Chromosomes Cancer. 2003 Apr;36(4):406-12.

PMID:
12619165
20.

The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6).

Boccuni P, MacGrogan D, Scandura JM, Nimer SD.

J Biol Chem. 2003 Apr 25;278(17):15412-20. Epub 2003 Feb 14.

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