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Items: 1 to 20 of 177


Obesogenic high-fat diet heightens aerobic glycolysis through hyperactivation of oncogenic KRAS.

Wang D, Bi Y, Hu L, Luo Y, Ji J, Mao AZ, Logsdon CD, Li E, Abbruzzese JL, Li Z, Yang VW, Lu W.

Cell Commun Signal. 2019 Feb 28;17(1):19. doi: 10.1186/s12964-019-0333-7.


Transgenic expression of cyclooxygenase-2 in pancreatic acinar cells induces chronic pancreatitis.

Huang H, Chen J, Peng L, Yao Y, Deng D, Zhang Y, Liu Y, Wang H, Li Z, Bi Y, Haddock AN, Zhan X, Lu W, Logsdon CD, Ji B.

Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1;316(1):G179-G186. doi: 10.1152/ajpgi.00096.2018. Epub 2018 Nov 15.


Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.

Zhou L, Husted H, Moore T, Lu M, Deng D, Liu Y, Ramachandran V, Arumugam T, Niehrs C, Wang H, Chiao P, Ling J, Curran MA, Maitra A, Hung MC, Lee JE, Logsdon CD, Hwang RF.

Sci Transl Med. 2018 Oct 24;10(464). pii: eaat3487. doi: 10.1126/scitranslmed.aat3487.


Galectin-3 Mediates Tumor Cell-Stroma Interactions by Activating Pancreatic Stellate Cells to Produce Cytokines via Integrin Signaling.

Zhao W, Ajani JA, Sushovan G, Ochi N, Hwang R, Hafley M, Johnson RL, Bresalier RS, Logsdon CD, Zhang Z, Song S.

Gastroenterology. 2018 Apr;154(5):1524-1537.e6. doi: 10.1053/j.gastro.2017.12.014. Epub 2017 Dec 21.


The immune system in cancer metastasis: friend or foe?

Janssen LME, Ramsay EE, Logsdon CD, Overwijk WW.

J Immunother Cancer. 2017 Oct 17;5(1):79. doi: 10.1186/s40425-017-0283-9. Review.


RAGE maintains high levels of NFκB and oncogenic Kras activity in pancreatic cancer.

Azizan N, Suter MA, Liu Y, Logsdon CD.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):592-597. doi: 10.1016/j.bbrc.2017.08.147. Epub 2017 Sep 1.


Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment.

Gomez-Chou SB, Swidnicka-Siergiejko AK, Badi N, Chavez-Tomar M, Lesinski GB, Bekaii-Saab T, Farren MR, Mace TA, Schmidt C, Liu Y, Deng D, Hwang RF, Zhou L, Moore T, Chatterjee D, Wang H, Leng X, Arlinghaus RB, Logsdon CD, Cruz-Monserrate Z.

Cancer Res. 2017 May 15;77(10):2647-2660. doi: 10.1158/0008-5472.CAN-16-1986. Epub 2017 Mar 1.


Chronic inflammation initiates multiple forms of K-Ras-independent mouse pancreatic cancer in the absence of TP53.

Swidnicka-Siergiejko AK, Gomez-Chou SB, Cruz-Monserrate Z, Deng D, Liu Y, Huang H, Ji B, Azizian N, Daniluk J, Lu W, Wang H, Maitra A, Logsdon CD.

Oncogene. 2017 Jun 1;36(22):3149-3158. doi: 10.1038/onc.2016.461. Epub 2016 Dec 19.


The MET Receptor Tyrosine Kinase Confers Repair of Murine Pancreatic Acinar Cells following Acute and Chronic Injury.

Gaziova I, Jackson D, Boor PJ, Carter D, Cruz-Monserrate Z, Elferink CJ, Joshi AD, Kaphalia B, Logsdon CD, Pereira de Castro K, Soong L, Tao X, Qiu S, Elferink LA.

PLoS One. 2016 Oct 31;11(10):e0165485. doi: 10.1371/journal.pone.0165485. eCollection 2016.


TM4SF1 Regulates Pancreatic Cancer Migration and Invasion In Vitro and In Vivo.

Cao J, Yang JC, Ramachandran V, Arumugam T, Deng DF, Li ZS, Xu LM, Logsdon CD.

Cell Physiol Biochem. 2016;39(2):740-50. doi: 10.1159/000445664. Epub 2016 Jul 27.


Acinar Ductal Metaplasia: Yap Fills a Gap.

Means AL, Logsdon CD.

Gastroenterology. 2016 Sep;151(3):393-5. doi: 10.1053/j.gastro.2016.07.022. Epub 2016 Jul 25. No abstract available.


The Significance of Ras Activity in Pancreatic Cancer Initiation.

Logsdon CD, Lu W.

Int J Biol Sci. 2016 Jan 28;12(3):338-46. doi: 10.7150/ijbs.15020. eCollection 2016. Review.


TM4SF1 Promotes Gemcitabine Resistance of Pancreatic Cancer In Vitro and In Vivo.

Cao J, Yang J, Ramachandran V, Arumugam T, Deng D, Li Z, Xu L, Logsdon CD.

PLoS One. 2015 Dec 28;10(12):e0144969. doi: 10.1371/journal.pone.0144969. eCollection 2015.


Ductal activation of oncogenic KRAS alone induces sarcomatoid phenotype.

Fu Y, Cruz-Monserrate Z, Helen Lin H, Chung Y, Ji B, Lin SM, Vonderfecht S, Logsdon CD, Li CF, Ann DK.

Sci Rep. 2015 Aug 20;5:13347. doi: 10.1038/srep13347.


Animal Models of Gastrointestinal and Liver Diseases. The difficulty of animal modeling of pancreatic cancer for preclinical evaluation of therapeutics.

Logsdon CD, Arumugam T, Ramachandran V.

Am J Physiol Gastrointest Liver Physiol. 2015 Sep 1;309(5):G283-91. doi: 10.1152/ajpgi.00169.2015. Epub 2015 Jul 9. Review.


New Blocking Antibodies against Novel AGR2-C4.4A Pathway Reduce Growth and Metastasis of Pancreatic Tumors and Increase Survival in Mice.

Arumugam T, Deng D, Bover L, Wang H, Logsdon CD, Ramachandran V.

Mol Cancer Ther. 2015 Apr;14(4):941-51. doi: 10.1158/1535-7163.MCT-14-0470. Epub 2015 Feb 2.


Preliminary evaluation of 1'-[(18)F]fluoroethyl-β-D-lactose ([(18)F]FEL) for detection of pancreatic cancer in nude mouse orthotopic xenografts.

Arumugam T, Paolillo V, Young D, Wen X, Logsdon CD, De Palatis L, Alauddin MM.

Nucl Med Biol. 2014 Nov-Dec;41(10):833-40. doi: 10.1016/j.nucmedbio.2014.08.001. Epub 2014 Aug 8.


Convergence of nanotechnology and cancer prevention: are we there yet?

Menter DG, Patterson SL, Logsdon CD, Kopetz S, Sood AK, Hawk ET.

Cancer Prev Res (Phila). 2014 Oct;7(10):973-92. doi: 10.1158/1940-6207.CAPR-14-0079. Epub 2014 Jul 24. Review.


Cell surface lactate receptor GPR81 is crucial for cancer cell survival.

Roland CL, Arumugam T, Deng D, Liu SH, Philip B, Gomez S, Burns WR, Ramachandran V, Wang H, Cruz-Monserrate Z, Logsdon CD.

Cancer Res. 2014 Sep 15;74(18):5301-10. doi: 10.1158/0008-5472.CAN-14-0319. Epub 2014 Jun 13.


Targeting pancreatic ductal adenocarcinoma acidic microenvironment.

Cruz-Monserrate Z, Roland CL, Deng D, Arumugam T, Moshnikova A, Andreev OA, Reshetnyak YK, Logsdon CD.

Sci Rep. 2014 Mar 19;4:4410. doi: 10.1038/srep04410.

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