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Items: 1 to 20 of 170

1.

Lower airway microbiota associates with inflammatory phenotype in severe preschool wheeze.

Robinson PFM, Pattaroni C, Cook J, Gregory L, Alonso AM, Fleming LJ, Lloyd CM, Bush A, Marsland BJ, Saglani S.

J Allergy Clin Immunol. 2018 Dec 20. pii: S0091-6749(18)32784-2. doi: 10.1016/j.jaci.2018.12.985. [Epub ahead of print]

2.

The ORMDL3 Asthma Gene Regulates ICAM1 and has Multiple Effects on Cellular Inflammation.

Zhang Y, Willis-Owen SAG, Spiegel S, Lloyd CM, Moffatt MF, Cookson WOCM.

Am J Respir Crit Care Med. 2018 Oct 19. doi: 10.1164/rccm.201803-0438OC. [Epub ahead of print]

PMID:
30339462
3.

Targeting the ICOS/ICOS-L pathway in a mouse model of established allergic asthma disrupts T follicular helper cell responses and ameliorates disease.

Uwadiae FI, Pyle CJ, Walker SA, Lloyd CM, Harker JA.

Allergy. 2018 Sep 16. doi: 10.1111/all.13602. [Epub ahead of print]

PMID:
30220084
4.

Inception of early-life allergen-induced airway hyperresponsiveness is reliant on IL-13+CD4+ T cells.

Saglani S, Gregory LG, Manghera AK, Branchett WJ, Uwadiae F, Entwistle LJ, Oliver RA, Vasiliou JE, Sherburn R, Lui S, Puttur F, Vöhringer D, Walker SA, Buckley J, Grychtol R, Fainardi V, Denney L, Byrne A, von Mutius E, Bush A, Lloyd CM.

Sci Immunol. 2018 Sep 7;3(27). pii: eaan4128. doi: 10.1126/sciimmunol.aan4128.

PMID:
30194239
5.

Pulmonary epithelial barrier and immunological functions at birth and in early life - key determinants of the development of asthma?  A description of the protocol for the Breathing Together study.

Turner S, Custovic A, Ghazal P, Grigg J, Gore M, Henderson J, Lloyd CM, Marsland B, Power UF, Roberts G, Saglani S, Schwarze J, Shields M, Bush A.

Wellcome Open Res. 2018 May 17;3:60. doi: 10.12688/wellcomeopenres.14489.1. eCollection 2018.

6.

An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness.

Patel DF, Peiró T, Shoemark A, Akthar S, Walker SA, Grabiec AM, Jackson PL, Hussell T, Gaggar A, Xu X, Trevor JL, Li J, Steele C, Tavernier G, Blalock JE, Niven RM, Gregory LG, Simpson A, Lloyd CM, Snelgrove RJ.

Sci Transl Med. 2018 Aug 22;10(455). pii: eaaq0693. doi: 10.1126/scitranslmed.aaq0693.

7.

Type 2 immunity: Expanding our view.

Lloyd CM, Snelgrove RJ.

Sci Immunol. 2018 Jul 6;3(25). pii: eaat1604. doi: 10.1126/sciimmunol.aat1604. Review.

8.

Epigenetic Control of Interleukin-9 in Asthma.

Lloyd CM, Harker JA.

N Engl J Med. 2018 Jul 5;379(1):87-89. doi: 10.1056/NEJMcibr1803610. No abstract available.

PMID:
29972761
9.

Tasting type 2 inflammation in the airways.

Snelgrove RJ, Lloyd CM.

J Allergy Clin Immunol. 2018 Aug;142(2):403-404. doi: 10.1016/j.jaci.2018.06.009. Epub 2018 Jun 19. No abstract available.

PMID:
29928925
10.

The enigmatic role of the neutrophil in asthma: Friend, foe or indifferent?

Snelgrove RJ, Patel DF, Patel T, Lloyd CM.

Clin Exp Allergy. 2018 Oct;48(10):1275-1285. doi: 10.1111/cea.13191. Epub 2018 Jul 11. Review.

PMID:
29900603
11.

Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma.

Zhang Y, Poobalasingam T, Yates LL, Walker SA, Taylor MS, Chessum L, Harrison J, Tsaprouni L, Adcock IM, Lloyd CM, Cookson WO, Moffatt MF, Dean CH.

Dis Model Mech. 2018 Jan 29;11(1). pii: dmm031369. doi: 10.1242/dmm.031369.

12.

Angiotensin-converting enzyme defines matrikine-regulated inflammation and fibrosis.

O'Reilly PJ, Ding Q, Akthar S, Cai G, Genschmer KR, Patel DF, Jackson PL, Viera L, Roda M, Locy ML, Bernstein EA, Lloyd CM, Bernstein KE, Snelgrove RJ, Blalock JE.

JCI Insight. 2017 Nov 16;2(22). pii: 91923. doi: 10.1172/jci.insight.91923. [Epub ahead of print]

13.

Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection.

Peiró T, Patel DF, Akthar S, Gregory LG, Pyle CJ, Harker JA, Birrell MA, Lloyd CM, Snelgrove RJ.

Thorax. 2018 Jun;73(6):546-556. doi: 10.1136/thoraxjnl-2017-210010. Epub 2017 Oct 27.

14.

Epithelial-derived TGF-β1 acts as a pro-viral factor in the lung during influenza A infection.

Denney L, Branchett W, Gregory LG, Oliver RA, Lloyd CM.

Mucosal Immunol. 2018 Mar;11(2):523-535. doi: 10.1038/mi.2017.77. Epub 2017 Oct 25.

15.

After asthma: redefining airways diseases.

Pavord ID, Beasley R, Agusti A, Anderson GP, Bel E, Brusselle G, Cullinan P, Custovic A, Ducharme FM, Fahy JV, Frey U, Gibson P, Heaney LG, Holt PG, Humbert M, Lloyd CM, Marks G, Martinez FD, Sly PD, von Mutius E, Wenzel S, Zar HJ, Bush A.

Lancet. 2018 Jan 27;391(10118):350-400. doi: 10.1016/S0140-6736(17)30879-6. Epub 2017 Sep 11. Review. No abstract available.

16.

Lung Alveolar Repair: Not All Cells Are Equal.

Dean CH, Lloyd CM.

Trends Mol Med. 2017 Oct;23(10):871-873. doi: 10.1016/j.molmed.2017.08.009. Epub 2017 Sep 1.

17.

An NLRP3, IL-1β, Neutrophil Axis in the Respiratory Tract Leaves You Breathless.

Snelgrove RJ, Lloyd CM.

Am J Respir Crit Care Med. 2017 Aug 1;196(3):253-254. doi: 10.1164/rccm.201703-0483ED. No abstract available.

18.

Development of allergic immunity in early life.

Lloyd CM, Saglani S.

Immunol Rev. 2017 Jul;278(1):101-115. doi: 10.1111/imr.12562. Review.

19.

Restoration of cutaneous pigmentation by transplantation to mice of isogeneic human melanocytes in dermal-epidermal engineered skin substitutes.

Boyce ST, Lloyd CM, Kleiner MC, Swope VB, Abdel-Malek Z, Supp DM.

Pigment Cell Melanoma Res. 2017 Jan;30(6):531-540. doi: 10.1111/pcmr.12609. Epub 2017 Oct 19.

PMID:
28640957
20.

Reply.

Löser S, Lloyd CM, Gregory LG.

J Allergy Clin Immunol. 2017 Oct;140(4):1211-1212. doi: 10.1016/j.jaci.2017.01.048. Epub 2017 Jun 16. No abstract available.

PMID:
28624350

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