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Items: 1 to 20 of 321

1.

Role of HSP90 in the Regulation of de Novo Purine Biosynthesis.

Pedley AM, Karras GI, Zhang X, Lindquist S, Benkovic SJ.

Biochemistry. 2018 Jun 12;57(23):3217-3221. doi: 10.1021/acs.biochem.8b00140. Epub 2018 Mar 23.

PMID:
29553718
2.

Yeast can accommodate phosphotyrosine: v-Src toxicity in yeast arises from a single disrupted pathway.

Kritzer JA, Freyzon Y, Lindquist S.

FEMS Yeast Res. 2018 May 1;18(3). doi: 10.1093/femsyr/foy027.

PMID:
29546391
3.

Translocon Declogger Ste24 Protects against IAPP Oligomer-Induced Proteotoxicity.

Kayatekin C, Amasino A, Gaglia G, Flannick J, Bonner JM, Fanning S, Narayan P, Barrasa MI, Pincus D, Landgraf D, Nelson J, Hesse WR, Costanzo M; AMP T2D-GENES Consortium, Myers CL, Boone C, Florez JC, Lindquist S.

Cell. 2018 Mar 22;173(1):62-73.e9. doi: 10.1016/j.cell.2018.02.026. Epub 2018 Mar 8.

PMID:
29526462
4.

An outbreak of Escherichia coli O157:H7 infections following a dairy education school field trip in Washington state, 2015.

Curran KG, Heiman Marshall KE, Singh T, Doobovsky Z, Hensley J, Melius B, Whitlock L, Stevenson L, Leinbach J, Oltean H, Glover WA, Kunesh T, Lindquist S, Williams I, Nichols M.

Epidemiol Infect. 2018 Mar;146(4):442-449. doi: 10.1017/S0950268817002862. Epub 2017 Dec 22.

PMID:
29271327
5.

FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome.

Caraveo G, Soste M, Cappelleti V, Fanning S, van Rossum DB, Whitesell L, Huang Y, Chung CY, Baru V, Zaichick S, Picotti P, Lindquist S.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11313-E11322. doi: 10.1073/pnas.1711926115. Epub 2017 Dec 11.

6.

Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy.

McLellan CA, Vincent BM, Solis NV, Lancaster AK, Sullivan LB, Hartland CL, Youngsaye W, Filler SG, Whitesell L, Lindquist S.

Nat Chem Biol. 2018 Feb;14(2):135-141. doi: 10.1038/nchembio.2534. Epub 2017 Dec 11.

7.

Notes from the Field: Absence of Asymptomatic Mumps Virus Shedding Among Vaccinated College Students During a Mumps Outbreak - Washington, February-June 2017.

Bonwitt J, Kawakami V, Wharton A, Burke RM, Murthy N, Lee A, Dell B, Kay M, Duchin J, Hickman C, McNall RJ, Rota PA, Patel M, Lindquist S, DeBolt C, Routh J.

MMWR Morb Mortal Wkly Rep. 2017 Dec 1;66(47):1307-1308. doi: 10.15585/mmwr.mm6647a5. No abstract available.

8.

Pioneer cells established by the [SWI+] prion can promote dispersal and out-crossing in yeast.

Newby GA, Lindquist S.

PLoS Biol. 2017 Nov 14;15(11):e2003476. doi: 10.1371/journal.pbio.2003476. eCollection 2017 Nov.

9.

A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance.

Newby GA, Kiriakov S, Hallacli E, Kayatekin C, Tsvetkov P, Mancuso CP, Bonner JM, Hesse WR, Chakrabortee S, Manogaran AL, Liebman SW, Lindquist S, Khalil AS.

Cell. 2017 Nov 2;171(4):966-979.e18. doi: 10.1016/j.cell.2017.09.041. Epub 2017 Oct 19.

PMID:
29056345
10.

Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells.

Dettmer U, Ramalingam N, von Saucken VE, Kim TE, Newman AJ, Terry-Kantor E, Nuber S, Ericsson M, Fanning S, Bartels T, Lindquist S, Levy OA, Selkoe D.

Hum Mol Genet. 2017 Sep 15;26(18):3466-3481. doi: 10.1093/hmg/ddx227.

PMID:
28911198
11.

Acute Flaccid Myelitis Among Children - Washington, September-November 2016.

Bonwitt J, Poel A, DeBolt C, Gonzales E, Lopez A, Routh J, Rietberg K, Linton N, Reggin J, Sejvar J, Lindquist S, Otten C.

MMWR Morb Mortal Wkly Rep. 2017 Aug 11;66(31):826-829. doi: 10.15585/mmwr.mm6631a2.

12.

Aggregation and Fibril Structure of AβM01-42 and Aβ1-42.

Silvers R, Colvin MT, Frederick KK, Jacavone AC, Lindquist S, Linse S, Griffin RG.

Biochemistry. 2017 Sep 12;56(36):4850-4859. doi: 10.1021/acs.biochem.7b00729. Epub 2017 Aug 30.

PMID:
28792214
13.

Dihydropyrimidine-Thiones and Clioquinol Synergize To Target β-Amyloid Cellular Pathologies through a Metal-Dependent Mechanism.

Tardiff DF, Brown LE, Yan X, Trilles R, Jui NT, Barrasa MI, Caldwell KA, Caldwell GA, Schaus SE, Lindquist S.

ACS Chem Neurosci. 2017 Sep 20;8(9):2039-2055. doi: 10.1021/acschemneuro.7b00187. Epub 2017 Jul 12.

PMID:
28628299
14.

Purification and characterization of recombinant human bile salt-stimulated lipase expressed in milk of transgenic cloned cows.

Wang Y, Ding F, Wang T, Liu W, Lindquist S, Hernell O, Wang J, Li J, Li L, Zhao Y, Dai Y, Li N.

PLoS One. 2017 May 5;12(5):e0176864. doi: 10.1371/journal.pone.0176864. eCollection 2017.

15.

Combining DNP NMR with segmental and specific labeling to study a yeast prion protein strain that is not parallel in-register.

Frederick KK, Michaelis VK, Caporini MA, Andreas LB, Debelouchina GT, Griffin RG, Lindquist S.

Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):3642-3647. doi: 10.1073/pnas.1619051114. Epub 2017 Mar 22.

16.

HSP90 Shapes the Consequences of Human Genetic Variation.

Karras GI, Yi S, Sahni N, Fischer M, Xie J, Vidal M, D'Andrea AD, Whitesell L, Lindquist S.

Cell. 2017 Feb 23;168(5):856-866.e12. doi: 10.1016/j.cell.2017.01.023. Epub 2017 Feb 16.

17.

In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons.

Chung CY, Khurana V, Yi S, Sahni N, Loh KH, Auluck PK, Baru V, Udeshi ND, Freyzon Y, Carr SA, Hill DE, Vidal M, Ting AY, Lindquist S.

Cell Syst. 2017 Feb 22;4(2):242-250.e4. doi: 10.1016/j.cels.2017.01.002. Epub 2017 Jan 25.

18.

Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways.

Khurana V, Peng J, Chung CY, Auluck PK, Fanning S, Tardiff DF, Bartels T, Koeva M, Eichhorn SW, Benyamini H, Lou Y, Nutter-Upham A, Baru V, Freyzon Y, Tuncbag N, Costanzo M, San Luis BJ, Schöndorf DC, Barrasa MI, Ehsani S, Sanjana N, Zhong Q, Gasser T, Bartel DP, Vidal M, Deleidi M, Boone C, Fraenkel E, Berger B, Lindquist S.

Cell Syst. 2017 Feb 22;4(2):157-170.e14. doi: 10.1016/j.cels.2016.12.011. Epub 2017 Jan 25.

19.

Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers.

Tsvetkov P, Sokol E, Jin D, Brune Z, Thiru P, Ghandi M, Garraway LA, Gupta PB, Santagata S, Whitesell L, Lindquist S.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):382-387. doi: 10.1073/pnas.1619067114. Epub 2016 Dec 27.

20.

Long-term functional outcomes after radical cystectomy with ileal bladder substitute: does the definition of continence matter?

Liedberg F, Ahlgren G, Baseckas G, Gudjonsson S, Håkansson U, Lindquist S, Löfgren A, Patschan O, Siller C, Sjödahl G.

Scand J Urol. 2017 Feb;51(1):44-49. doi: 10.1080/21681805.2016.1249943. Epub 2016 Nov 11.

PMID:
27834115

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