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Items: 1 to 20 of 133

1.

Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway.

Bugaj LJ, Sabnis AJ, Mitchell A, Garbarino JE, Toettcher JE, Bivona TG, Lim WA.

Science. 2018 Aug 31;361(6405). pii: eaao3048. doi: 10.1126/science.aao3048.

PMID:
30166458
2.

Significant and conservative long-range transport of dissolved organic nutrients in the Changjiang diluted water.

Kwon HK, Kim G, Hwang J, Lim WA, Park JW, Kim TH.

Sci Rep. 2018 Aug 24;8(1):12768. doi: 10.1038/s41598-018-31105-1.

3.

Programming self-organizing multicellular structures with synthetic cell-cell signaling.

Toda S, Blauch LR, Tang SKY, Morsut L, Lim WA.

Science. 2018 Jul 13;361(6398):156-162. doi: 10.1126/science.aat0271. Epub 2018 May 31.

PMID:
29853554
4.

Building a Stable Relationship: Ensuring Homeostasis among Cell Types within a Tissue.

Frankel NW, Lim WA.

Cell. 2018 Feb 8;172(4):638-640. doi: 10.1016/j.cell.2018.01.024.

PMID:
29425483
5.

CpMCA, a novel metacaspase gene from the harmful dinoflagellate Cochlodinium polykrikoides and its expression during cell death.

Wang H, Park BS, Lim WA, Ki JS.

Gene. 2018 Apr 20;651:70-78. doi: 10.1016/j.gene.2018.02.002. Epub 2018 Feb 3.

PMID:
29408405
6.

Design of Tunable Oscillatory Dynamics in a Synthetic NF-κB Signaling Circuit.

Zhang ZB, Wang QY, Ke YX, Liu SY, Ju JQ, Lim WA, Tang C, Wei P.

Cell Syst. 2017 Nov 22;5(5):460-470.e5. doi: 10.1016/j.cels.2017.09.016. Epub 2017 Oct 25.

7.

Which species, Alexandrium catenella (Group I) or A. pacificum (Group IV), is really responsible for past paralytic shellfish poisoning outbreaks in Jinhae-Masan Bay, Korea?

Shin HH, Li Z, Kim ES, Park JW, Lim WA.

Harmful Algae. 2017 Sep;68:31-39. doi: 10.1016/j.hal.2017.07.006. Epub 2017 Jul 26.

PMID:
28962988
8.

Tracing Information Flow from Erk to Target Gene Induction Reveals Mechanisms of Dynamic and Combinatorial Control.

Wilson MZ, Ravindran PT, Lim WA, Toettcher JE.

Mol Cell. 2017 Sep 7;67(5):757-769.e5. doi: 10.1016/j.molcel.2017.07.016. Epub 2017 Aug 17.

9.

Formation and germination of temporary cysts of Cochlodinium polykrikoides Margalef (Dinophyceae) and their ecological role in dense blooms.

Shin HH, Li Z, Yoon YH, Oh SJ, Lim WA.

Harmful Algae. 2017 Jun;66:57-64. doi: 10.1016/j.hal.2017.05.002. Epub 2017 May 15.

PMID:
28602254
10.

Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities.

Roybal KT, Lim WA.

Annu Rev Immunol. 2017 Apr 26;35:229-253. doi: 10.1146/annurev-immunol-051116-052302. Review.

11.

CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells.

Rupp LJ, Schumann K, Roybal KT, Gate RE, Ye CJ, Lim WA, Marson A.

Sci Rep. 2017 Apr 7;7(1):737. doi: 10.1038/s41598-017-00462-8.

12.

The Principles of Engineering Immune Cells to Treat Cancer.

Lim WA, June CH.

Cell. 2017 Feb 9;168(4):724-740. doi: 10.1016/j.cell.2017.01.016. Review.

13.

Interrogating cellular perception and decision making with optogenetic tools.

Bugaj LJ, O'Donoghue GP, Lim WA.

J Cell Biol. 2017 Jan 2;216(1):25-28. doi: 10.1083/jcb.201612094. Epub 2016 Dec 21.

14.

Engineering Therapeutic T Cells: From Synthetic Biology to Clinical Trials.

Esensten JH, Bluestone JA, Lim WA.

Annu Rev Pathol. 2017 Jan 24;12:305-330. doi: 10.1146/annurev-pathol-052016-100304. Epub 2016 Dec 5. Review.

15.

Engineering dynamical control of cell fate switching using synthetic phospho-regulons.

Gordley RM, Williams RE, Bashor CJ, Toettcher JE, Yan S, Lim WA.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13528-13533. Epub 2016 Nov 7.

16.

Complex transcriptional modulation with orthogonal and inducible dCas9 regulators.

Gao Y, Xiong X, Wong S, Charles EJ, Lim WA, Qi LS.

Nat Methods. 2016 Dec;13(12):1043-1049. doi: 10.1038/nmeth.4042. Epub 2016 Oct 24.

17.

Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors.

Roybal KT, Williams JZ, Morsut L, Rupp LJ, Kolinko I, Choe JH, Walker WJ, McNally KA, Lim WA.

Cell. 2016 Oct 6;167(2):419-432.e16. doi: 10.1016/j.cell.2016.09.011. Epub 2016 Sep 29.

18.

Modular engineering of cellular signaling proteins and networks.

Gordley RM, Bugaj LJ, Lim WA.

Curr Opin Struct Biol. 2016 Aug;39:106-114. doi: 10.1016/j.sbi.2016.06.012. Epub 2016 Jul 15. Review.

19.

Genome-wide analysis of transcription and photosynthesis inhibition in the harmful dinoflagellate Prorocentrum minimum in response to the biocide copper sulfate.

Guo R, Lim WA, Ki JS.

Harmful Algae. 2016 Jul;57(Pt A):27-38. doi: 10.1016/j.hal.2016.05.004. Epub 2016 Jun 9.

PMID:
30170719
20.

CRISPR/Cas9 for Human Genome Engineering and Disease Research.

Xiong X, Chen M, Lim WA, Zhao D, Qi LS.

Annu Rev Genomics Hum Genet. 2016 Aug 31;17:131-54. doi: 10.1146/annurev-genom-083115-022258. Epub 2016 May 23. Review.

PMID:
27216776

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