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Items: 19


Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice.

Chalermpalanupap T, Schroeder JP, Rorabaugh JM, Liles LC, Lah JJ, Levey AI, Weinshenker D.

J Neurosci. 2018 Jan 3;38(1):74-92. doi: 10.1523/JNEUROSCI.1483-17.2017. Epub 2017 Nov 13.


Noradrenergic regulation of plasticity marker expression in the adult rodent piriform cortex.

Vadodaria KC, Yanpallewar SU, Vadhvani M, Toshniwal D, Liles LC, Rommelfanger KS, Weinshenker D, Vaidya VA.

Neurosci Lett. 2017 Mar 22;644:76-82. doi: 10.1016/j.neulet.2017.02.060. Epub 2017 Feb 23.


Human Bacterial Artificial Chromosome (BAC) Transgenesis Fully Rescues Noradrenergic Function in Dopamine β-Hydroxylase Knockout Mice.

Cubells JF, Schroeder JP, Barrie ES, Manvich DF, Sadee W, Berg T, Mercer K, Stowe TA, Liles LC, Squires KE, Mezher A, Curtin P, Perdomo DL, Szot P, Weinshenker D.

PLoS One. 2016 May 5;11(5):e0154864. doi: 10.1371/journal.pone.0154864. eCollection 2016.


Norepinephrine is necessary for experience-dependent plasticity in the developing mouse auditory cortex.

Shepard KN, Liles LC, Weinshenker D, Liu RC.

J Neurosci. 2015 Feb 11;35(6):2432-7. doi: 10.1523/JNEUROSCI.0532-14.2015.


Chronic inhibition of dopamine β-hydroxylase facilitates behavioral responses to cocaine in mice.

Gaval-Cruz M, Liles LC, Iuvone PM, Weinshenker D.

PLoS One. 2012;7(11):e50583. doi: 10.1371/journal.pone.0050583. Epub 2012 Nov 27.


Behavioral responses of dopamine beta-hydroxylase knockout mice to modafinil suggest a dual noradrenergic-dopaminergic mechanism of action.

Mitchell HA, Bogenpohl JW, Liles LC, Epstein MP, Bozyczko-Coyne D, Williams M, Weinshenker D.

Pharmacol Biochem Behav. 2008 Dec;91(2):217-22. doi: 10.1016/j.pbb.2008.07.014. Epub 2008 Jul 25. Erratum in: Pharmacol Biochem Behav. 2009 Mar;92(1):197.


Effects of disulfiram and dopamine beta-hydroxylase knockout on cocaine-induced seizures.

Gaval-Cruz M, Schroeder JP, Liles LC, Javors MA, Weinshenker D.

Pharmacol Biochem Behav. 2008 Jun;89(4):556-62. doi: 10.1016/j.pbb.2008.02.009. Epub 2008 Feb 12.


Norepinephrine signaling through beta-adrenergic receptors is critical for expression of cocaine-induced anxiety.

Schank JR, Liles LC, Weinshenker D.

Biol Psychiatry. 2008 Jun 1;63(11):1007-12. Epub 2008 Feb 20.


Genetic or pharmacological blockade of noradrenaline synthesis enhances the neurochemical, behavioral, and neurotoxic effects of methamphetamine.

Weinshenker D, Ferrucci M, Busceti CL, Biagioni F, Lazzeri G, Liles LC, Lenzi P, Pasquali L, Murri L, Paparelli A, Fornai F.

J Neurochem. 2008 Apr;105(2):471-83. Epub 2007 Nov 26.


Norepinephrine loss produces more profound motor deficits than MPTP treatment in mice.

Rommelfanger KS, Edwards GL, Freeman KG, Liles LC, Miller GW, Weinshenker D.

Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13804-9. Epub 2007 Aug 16.


The effects of norepinephrine transporter inactivation on locomotor activity in mice.

Mitchell HA, Ahern TH, Liles LC, Javors MA, Weinshenker D.

Biol Psychiatry. 2006 Nov 15;60(10):1046-52. Epub 2006 Aug 7.


The full expression of fasting-induced torpor requires beta 3-adrenergic receptor signaling.

Swoap SJ, Gutilla MJ, Liles LC, Smith RO, Weinshenker D.

J Neurosci. 2006 Jan 4;26(1):241-5.


Dopamine beta-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine.

Schank JR, Ventura R, Puglisi-Allegra S, Alcaro A, Cole CD, Liles LC, Seeman P, Weinshenker D.

Neuropsychopharmacology. 2006 Oct;31(10):2221-30. Epub 2005 Dec 14.


A ketogenic diet and knockout of the norepinephrine transporter both reduce seizure severity in mice.

Martillotti J, Weinshenker D, Liles LC, Eagles DA.

Epilepsy Res. 2006 Mar;68(3):207-11. Epub 2005 Dec 13.


Effects of dopamine beta-hydroxylase genotype and disulfiram inhibition on catecholamine homeostasis in mice.

Bourdélat-Parks BN, Anderson GM, Donaldson ZR, Weiss JM, Bonsall RW, Emery MS, Liles LC, Weinshenker D.

Psychopharmacology (Berl). 2005 Nov;183(1):72-80. Epub 2005 Oct 22.


The effects of chronic norepinephrine transporter inactivation on seizure susceptibility in mice.

Ahern TH, Javors MA, Eagles DA, Martillotti J, Mitchell HA, Liles LC, Weinshenker D.

Neuropsychopharmacology. 2006 Apr;31(4):730-8.


Reduced anticonvulsant efficacy of valproic acid in dopamine beta-hydroxylase knockout mice.

Schank JR, Liles LC, Weinshenker D.

Epilepsy Res. 2005 Jun;65(1-2):23-31.


The ketogenic diet does not alter brain expression of orexigenic neuropeptides.

Tabb K, Szot P, White SS, Liles LC, Weinshenker D.

Epilepsy Res. 2004 Nov;62(1):35-9.


The anticonvulsant and proconvulsant effects of alpha2-adrenoreceptor agonists are mediated by distinct populations of alpha2A-adrenoreceptors.

Szot P, Lester M, Laughlin ML, Palmiter RD, Liles LC, Weinshenker D.

Neuroscience. 2004;126(3):795-803.


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