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Items: 1 to 20 of 115

1.

Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription.

Israel JW, Chappell GA, Simon JM, Pott S, Safi A, Lewis L, Cotney P, Boulos HS, Bodnar W, Lieb JD, Crawford GE, Furey TS, Rusyn I.

Mamm Genome. 2018 Feb;29(1-2):153-167. doi: 10.1007/s00335-018-9739-6. Epub 2018 Feb 10.

PMID:
29429127
2.

Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice.

Chappell GA, Israel JW, Simon JM, Pott S, Safi A, Eklund K, Sexton KG, Bodnar W, Lieb JD, Crawford GE, Rusyn I, Furey TS.

Environ Health Perspect. 2017 Oct 16;125(10):107006. doi: 10.1289/EHP1937.

3.

Nucleosome fragility is associated with future transcriptional response to developmental cues and stress in C. elegans.

Jeffers TE, Lieb JD.

Genome Res. 2017 Jan;27(1):75-86. doi: 10.1101/gr.208173.116. Epub 2016 Nov 14.

4.

Chromatin profiling of Drosophila CNS subpopulations identifies active transcriptional enhancers.

Pearson JC, McKay DJ, Lieb JD, Crews ST.

Development. 2016 Oct 15;143(20):3723-3732.

5.

Cisplatin DNA damage and repair maps of the human genome at single-nucleotide resolution.

Hu J, Lieb JD, Sancar A, Adar S.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11507-11512. Epub 2016 Sep 29.

6.

A Transcriptional Lineage of the Early C. elegans Embryo.

Tintori SC, Osborne Nishimura E, Golden P, Lieb JD, Goldstein B.

Dev Cell. 2016 Aug 22;38(4):430-44. doi: 10.1016/j.devcel.2016.07.025.

7.

Alterations to chromatin in intestinal macrophages link IL-10 deficiency to inappropriate inflammatory responses.

Simon JM, Davis JP, Lee SE, Schaner MR, Gipson GR, Weiser M, Sartor RB, Herfarth HH, Rahbar R, Sadiq TS, Koruda MJ, McGovern DP, Lieb JD, Mohlke KL, Furey TS, Sheikh SZ.

Eur J Immunol. 2016 Aug;46(8):1912-25. doi: 10.1002/eji.201546237. Epub 2016 Jun 1.

8.

Genome-wide kinetics of DNA excision repair in relation to chromatin state and mutagenesis.

Adar S, Hu J, Lieb JD, Sancar A.

Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):E2124-33. doi: 10.1073/pnas.1603388113. Epub 2016 Mar 28.

9.

The function and regulation of the GATA factor ELT-2 in the C. elegans endoderm.

Wiesenfahrt T, Berg JY, Osborne Nishimura E, Robinson AG, Goszczynski B, Lieb JD, McGhee JD.

Development. 2016 Feb 1;143(3):483-91. doi: 10.1242/dev.130914. Epub 2015 Dec 23.

10.

Zelda is differentially required for chromatin accessibility, transcription factor binding, and gene expression in the early Drosophila embryo.

Schulz KN, Bondra ER, Moshe A, Villalta JE, Lieb JD, Kaplan T, McKay DJ, Harrison MM.

Genome Res. 2015 Nov;25(11):1715-26. doi: 10.1101/gr.192682.115. Epub 2015 Sep 2.

11.

Single-cell ATAC-seq: strength in numbers.

Pott S, Lieb JD.

Genome Biol. 2015 Aug 21;16:172. doi: 10.1186/s13059-015-0737-7.

12.

Histone modifications predispose genome regions to breakage and translocation.

Burman B, Zhang ZZ, Pegoraro G, Lieb JD, Misteli T.

Genes Dev. 2015 Jul 1;29(13):1393-402. doi: 10.1101/gad.262170.115. Epub 2015 Jun 23.

13.

Genome-wide analysis of human global and transcription-coupled excision repair of UV damage at single-nucleotide resolution.

Hu J, Adar S, Selby CP, Lieb JD, Sancar A.

Genes Dev. 2015 May 1;29(9):948-60. doi: 10.1101/gad.261271.115.

14.

Correction: Quantitative genetics of CTCF binding reveal local sequence effects and different modes of X-chromosome association.

Ding Z, Ni Y, Timmer SW, Lee BK, Battenhouse A, Louzada S, Yang F, Dunham I, Crawford GE, Lieb JD, Durbin R, Iyer VR, Birney E.

PLoS Genet. 2015 Apr 28;11(4):e1005177. doi: 10.1371/journal.pgen.1005177. eCollection 2015 Apr.

15.

Asymmetric transcript discovery by RNA-seq in C. elegans blastomeres identifies neg-1, a gene important for anterior morphogenesis.

Osborne Nishimura E, Zhang JC, Werts AD, Goldstein B, Lieb JD.

PLoS Genet. 2015 Apr 13;11(4):e1005117. doi: 10.1371/journal.pgen.1005117. eCollection 2015 Apr.

16.

STAT3 acts through pre-existing nucleosome-depleted regions bound by FOS during an epigenetic switch linking inflammation to cancer.

Fleming JD, Giresi PG, Lindahl-Allen M, Krall EB, Lieb JD, Struhl K.

Epigenetics Chromatin. 2015 Feb 14;8:7. doi: 10.1186/1756-8935-8-7. eCollection 2015.

17.

Interrogating the function of metazoan histones using engineered gene clusters.

McKay DJ, Klusza S, Penke TJ, Meers MP, Curry KP, McDaniel SL, Malek PY, Cooper SW, Tatomer DC, Lieb JD, Strahl BD, Duronio RJ, Matera AG.

Dev Cell. 2015 Feb 9;32(3):373-86. doi: 10.1016/j.devcel.2014.12.025.

18.

Ancient transposable elements transformed the uterine regulatory landscape and transcriptome during the evolution of mammalian pregnancy.

Lynch VJ, Nnamani MC, Kapusta A, Brayer K, Plaza SL, Mazur EC, Emera D, Sheikh SZ, Grützner F, Bauersachs S, Graf A, Young SL, Lieb JD, DeMayo FJ, Feschotte C, Wagner GP.

Cell Rep. 2015 Feb 3;10(4):551-61. doi: 10.1016/j.celrep.2014.12.052. Epub 2015 Jan 29.

19.

What are super-enhancers?

Pott S, Lieb JD.

Nat Genet. 2015 Jan;47(1):8-12. doi: 10.1038/ng.3167.

PMID:
25547603
20.

A split personality for nucleosomes.

McKay DJ, Lieb JD.

Cell. 2014 Dec 4;159(6):1249-51. doi: 10.1016/j.cell.2014.11.030.

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