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Items: 1 to 20 of 197

1.

Design, Biological Evaluation and Molecular Modelling of Tetrahydroisoquinoline Derivatives: Discovery of A Potent P-glycoprotein Ligand Overcoming Multi-Drug Resistance in Cancer Stem Cells.

Riganti C, Contino M, Guglielmo S, Perrone MG, Salaroglio IC, Milosevic V, Giampietro R, Leonetti F, Rolando B, Lazzarato L, Colabufo NA, Fruttero R.

J Med Chem. 2018 Dec 25. doi: 10.1021/acs.jmedchem.8b01655. [Epub ahead of print]

PMID:
30584838
2.

A new approach for drug target and bioactivity prediction: the Multi-fingerprint Similarity Search aLgorithm (MuSSeL).

Alberga D, Trisciuzzi D, Montaruli M, Leonetti F, Mangiatordi GF, Nicolotti O.

J Chem Inf Model. 2018 Nov 28. doi: 10.1021/acs.jcim.8b00698. [Epub ahead of print]

PMID:
30485097
3.

Variability in genes regulating vitamin D metabolism is associated with vitamin D levels in type 2 diabetes.

Bertoccini L, Bailetti D; SUMMER Study in Diabetes Group, Buzzetti R, Cavallo MG, Copetti M, Cossu E, D'Angelo P, De Cosmo S, Di Mauro L, Leonetti F, Morano S, Morviducci L, Napoli N, Prudente S, Pugliese G, Trischitta V, Baroni MG.

Oncotarget. 2018 Oct 9;9(79):34911-34918. doi: 10.18632/oncotarget.26178. eCollection 2018 Oct 9.

4.

Evidence of diabetes-specific autoimmunity in obese subjects with normal glucose tolerance.

Tiberti C, Zampetti S, Capoccia D, Campagna G, Lucantoni F, Anastasi E, Pallotta L, Panimolle F, Leto G, Lenzi A, Leonetti F, Buzzetti R.

Diabetes Metab Res Rev. 2018 Nov;34(8):e3055. doi: 10.1002/dmrr.3055. Epub 2018 Aug 31.

PMID:
30129269
5.

Ion Channels in Drug Discovery and Safety Pharmacology.

Imbrici P, Nicolotti O, Leonetti F, Conte D, Liantonio A.

Methods Mol Biol. 2018;1800:313-326. doi: 10.1007/978-1-4939-7899-1_15.

PMID:
29934900
6.

Molecular Docking for Predictive Toxicology.

Trisciuzzi D, Alberga D, Leonetti F, Novellino E, Nicolotti O, Mangiatordi GF.

Methods Mol Biol. 2018;1800:181-197. doi: 10.1007/978-1-4939-7899-1_8.

PMID:
29934893
7.

Gut Microbiota Markers in Obese Adolescent and Adult Patients: Age-Dependent Differential Patterns.

Del Chierico F, Abbatini F, Russo A, Quagliariello A, Reddel S, Capoccia D, Caccamo R, Ginanni Corradini S, Nobili V, De Peppo F, Dallapiccola B, Leonetti F, Silecchia G, Putignani L.

Front Microbiol. 2018 Jun 5;9:1210. doi: 10.3389/fmicb.2018.01210. eCollection 2018.

8.

Neurotensin Is a Lipid-Induced Gastrointestinal Peptide Associated with Visceral Adipose Tissue Inflammation in Obesity.

Barchetta I, Cimini FA, Capoccia D, Bertoccini L, Ceccarelli V, Chiappetta C, Leonetti F, Di Cristofano C, Silecchia G, Orho-Melander M, Melander O, Cavallo MG.

Nutrients. 2018 Apr 23;10(4). pii: E526. doi: 10.3390/nu10040526.

9.

Automated identification of structurally heterogeneous and patentable antiproliferative hits as potential tubulin inhibitors.

Mangiatordi GF, Trisciuzzi D, Iacobazzi R, Denora N, Pisani L, Catto M, Leonetti F, Alberga D, Nicolotti O.

Chem Biol Drug Des. 2018 Jul;92(1):1161-1170. doi: 10.1111/cbdd.13200. Epub 2018 Apr 27.

PMID:
29633572
10.

Increased Plasma Proneurotensin Levels Identify NAFLD in Adults With and Without Type 2 Diabetes.

Barchetta I, Cimini FA, Leonetti F, Capoccia D, Di Cristofano C, Silecchia G, Orho-Melander M, Melander O, Cavallo MG.

J Clin Endocrinol Metab. 2018 Jun 1;103(6):2253-2260. doi: 10.1210/jc.2017-02751.

PMID:
29590379
11.

Mapping ligand binding pockets in chloride ClC-1 channels through an integrated in silico and experimental approach using anthracene-9-carboxylic acid and niflumic acid.

Altamura C, Mangiatordi GF, Nicolotti O, Sahbani D, Farinato A, Leonetti F, Carratù MR, Conte D, Desaphy JF, Imbrici P.

Br J Pharmacol. 2018 May;175(10):1770-1780. doi: 10.1111/bph.14192. Epub 2018 Apr 6.

PMID:
29500929
12.

Long-term Metabolic Effects of Laparoscopic Sleeve Gastrectomy.

Capoccia D, Coccia F, Guarisco G, Testa M, Rendina R, Abbatini F, Silecchia G, Leonetti F.

Obes Surg. 2018 Aug;28(8):2289-2296. doi: 10.1007/s11695-018-3153-8.

PMID:
29497961
13.

Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds.

Stefanachi A, Leonetti F, Pisani L, Catto M, Carotti A.

Molecules. 2018 Jan 27;23(2). pii: E250. doi: 10.3390/molecules23020250. Review.

14.

WISP1 Is a Marker of Systemic and Adipose Tissue Inflammation in Dysmetabolic Subjects With or Without Type 2 Diabetes.

Barchetta I, Cimini FA, Capoccia D, De Gioannis R, Porzia A, Mainiero F, Di Martino M, Bertoccini L, De Bernardinis M, Leonetti F, Baroni MG, Lenzi A, Cavallo MG.

J Endocr Soc. 2017 Apr 18;1(6):660-670. doi: 10.1210/js.2017-00108. eCollection 2017 Jun 1.

15.

Investigating Structural Requirements for the Antiproliferative Activity of Biphenyl Nicotinamides.

Majellaro M, Stefanachi A, Tardia P, Vicenti C, Boccarelli A, Pannunzio A, Campanella F, Coluccia M, Denora N, Leonetti F, de Candia M, Altomare CD, Cellamare S.

ChemMedChem. 2017 Aug 22;12(16):1380-1389. doi: 10.1002/cmdc.201700365. Epub 2017 Aug 3.

PMID:
28665505
16.

Effects of basic traditional Chinese diet on body mass index, lean body mass, and eating and hunger behaviours in overweight or obese individuals.

Leonetti F, Liguori A, Petti F, Rughini S, Silli L, Liguori S, Bangrazi S.

J Tradit Chin Med. 2016 Aug;36(4):456-63.

17.

Laparoscopic Sleeve Gastrectomy Changes in the Last Decade: Differences in Morbidity and Weight Loss.

Balla A, Quaresima S, Leonetti F, Paone E, Brunori M, Messina T, Seitaj A, Paganini AM.

J Laparoendosc Adv Surg Tech A. 2017 Nov;27(11):1165-1171. doi: 10.1089/lap.2017.0059. Epub 2017 Apr 21.

PMID:
28430045
18.

The vitamin D receptor functional variant rs2228570 (C>T) does not associate with type 2 diabetes mellitus.

Bertoccini L, Sentinelli F, Leonetti F, Bailetti D, Capoccia D, Cimini FA, Barchetta I, Incani M, Lenzi A, Cossu E, Cavallo MG, Baroni MG.

Endocr Res. 2017 Nov;42(4):331-335. doi: 10.1080/07435800.2017.1305965. Epub 2017 Apr 7.

PMID:
28388281
19.

Assessing the association between 25-OH vitamin D levels and ROMA score in a population of obese women.

Anastasi E, Capoccia D, Granato T, Viggiani V, Tartaglione S, Manganaro L, Angeloni A, Leonetti F.

J Biol Regul Homeost Agents. 2016 Oct-Dec;30(4):1165-1171.

PMID:
28078870
20.

Implementing the Risk of Ovarian Malignancy Algorithm Adding Obesity as a Predictive Factor.

Anastasi E, Capoccia D, Granato T, Silecchia G, Rizzello M, Porpora MG, Frati L, Angeloni A, Leonetti F.

Anticancer Res. 2016 Dec;36(12):6425-6429.

PMID:
27919964

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