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Items: 1 to 20 of 446

1.

Pulsed resource availability changes dietary niche breadth and partitioning between generalist rodent consumers.

Stephens RB, Hobbie EA, Lee TD, Rowe RJ.

Ecol Evol. 2019 Aug 20;9(18):10681-10693. doi: 10.1002/ece3.5587. eCollection 2019 Sep.

2.

A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.

Lee TD, Lee OW, Brimacombe KR, Chen L, Guha R, Lusvarghi S, Tebase BG, Klumpp-Thomas C, Robey RW, Ambudkar SV, Shen M, Gottesman MM, Hall MD.

Mol Pharmacol. 2019 Nov;96(5):629-640. doi: 10.1124/mol.119.115964. Epub 2019 Sep 12.

3.

Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.

Lee OW, Austin S, Gamma M, Cheff DM, Lee TD, Wilson KM, Johnson J, Travers J, Braisted JC, Guha R, Klumpp-Thomas C, Shen M, Hall MD.

SLAS Discov. 2019 Sep 9:2472555219873068. doi: 10.1177/2472555219873068. [Epub ahead of print]

PMID:
31498718
4.

An open-label trial of cryopreserved human umbilical cord in the treatment of complex diabetic foot ulcers complicated by osteomyelitis.

Marston WA, Lantis JC 2nd, Wu SC, Nouvong A, Lee TD, McCoy ND, Slade HB, Tseng SC.

Wound Repair Regen. 2019 Nov;27(6):680-686. doi: 10.1111/wrr.12754. Epub 2019 Aug 19.

PMID:
31376297
5.

Strong photosynthetic acclimation and enhanced water-use efficiency in grassland functional groups persist over 21 years of CO2 enrichment, independent of nitrogen supply.

Pastore MA, Lee TD, Hobbie SE, Reich PB.

Glob Chang Biol. 2019 Sep;25(9):3031-3044. doi: 10.1111/gcb.14714. Epub 2019 Jun 24.

PMID:
31148322
6.

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.

Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, Dorjsuren D, Eastman RT, Huang R, Iannotti MJ, Karavadhi S, Klumpp-Thomas C, Roth JS, Sakamuru S, Sun W, Titus SA, Yasgar A, Zhang YQ, Zhao J, Andrade RB, Brown MK, Burns NZ, Cha JK, Mevers EE, Clardy J, Clement JA, Crooks PA, Cuny GD, Ganor J, Moreno J, Morrill LA, Picazo E, Susick RB, Garg NK, Goess BC, Grossman RB, Hughes CC, Johnston JN, Joullie MM, Kinghorn AD, Kingston DGI, Krische MJ, Kwon O, Maimone TJ, Majumdar S, Maloney KN, Mohamed E, Murphy BT, Nagorny P, Olson DE, Overman LE, Brown LE, Snyder JK, Porco JA Jr, Rivas F, Ross SA, Sarpong R, Sharma I, Shaw JT, Xu Z, Shen B, Shi W, Stephenson CRJ, Verano AL, Tan DS, Tang Y, Taylor RE, Thomson RJ, Vosburg DA, Wu J, Wuest WM, Zakarian A, Zhang Y, Ren T, Zuo Z, Inglese J, Michael S, Simeonov A, Zheng W, Shinn P, Jadhav A, Boxer MB, Hall MD, Xia M, Guha R, Rohde JM.

ACS Cent Sci. 2018 Dec 26;4(12):1727-1741. doi: 10.1021/acscentsci.8b00747. Epub 2018 Dec 5.

7.

Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme.

Li YJ, Du L, Wang J, Vega R, Lee TD, Miao Y, Aldana-Masangkay G, Samuels ER, Li B, Ouyang SX, Colayco SA, Bobkova EV, Divlianska DB, Sergienko E, Chung TDY, Fakih M, Chen Y.

Cell Chem Biol. 2019 Feb 21;26(2):278-288.e6. doi: 10.1016/j.chembiol.2018.10.026. Epub 2018 Dec 20.

PMID:
30581133
8.

Response to Comment on "Unexpected reversal of C3 versus C4 grass response to elevated CO2 during a 20-year field experiment".

Reich PB, Hobbie SE, Lee TD, Pastore MA.

Science. 2018 Sep 14;361(6407). pii: eaau8982. doi: 10.1126/science.aau8982.

PMID:
30213887
9.

Adoption of E-Government Applications for Public Health Risk Communication: Government Trust and Social Media Competence as Primary Drivers.

Park H, Lee TD.

J Health Commun. 2018;23(8):712-723. doi: 10.1080/10810730.2018.1511013. Epub 2018 Aug 29.

PMID:
30156964
10.

Response to Comment on "Unexpected reversal of C3 versus C4 grass response to elevated CO2 during a 20-year field experiment".

Reich PB, Hobbie SE, Lee TD, Pastore MA.

Science. 2018 Aug 10;361(6402). pii: eaau1300. doi: 10.1126/science.aau1300.

PMID:
30093575
11.

Unexpected reversal of C3 versus C4 grass response to elevated CO2 during a 20-year field experiment.

Reich PB, Hobbie SE, Lee TD, Pastore MA.

Science. 2018 Apr 20;360(6386):317-320. doi: 10.1126/science.aas9313.

PMID:
29674593
12.

Use of genomics to design a diagnostic assay to discriminate between Streptococcus pneumoniae and Streptococcus pseudopneumoniae.

Croxen MA, Lee TD, Azana R, Hoang LM.

Microb Genom. 2018 Jul;4(7). doi: 10.1099/mgen.0.000175. Epub 2018 Apr 9.

13.

Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors.

Rohde JM, Brimacombe KR, Liu L, Pacold ME, Yasgar A, Cheff DM, Lee TD, Rai G, Baljinnyam B, Li Z, Simeonov A, Hall MD, Shen M, Sabatini DM, Boxer MB.

Bioorg Med Chem. 2018 May 1;26(8):1727-1739. doi: 10.1016/j.bmc.2018.02.016. Epub 2018 Feb 27.

14.

The nasal microbiome in asthma.

Fazlollahi M, Lee TD, Andrade J, Oguntuyo K, Chun Y, Grishina G, Grishin A, Bunyavanich S.

J Allergy Clin Immunol. 2018 Sep;142(3):834-843.e2. doi: 10.1016/j.jaci.2018.02.020. Epub 2018 Mar 5.

15.

Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH).

Rai G, Brimacombe KR, Mott BT, Urban DJ, Hu X, Yang SM, Lee TD, Cheff DM, Kouznetsova J, Benavides GA, Pohida K, Kuenstner EJ, Luci DK, Lukacs CM, Davies DR, Dranow DM, Zhu H, Sulikowski G, Moore WJ, Stott GM, Flint AJ, Hall MD, Darley-Usmar VM, Neckers LM, Dang CV, Waterson AG, Simeonov A, Jadhav A, Maloney DJ.

J Med Chem. 2017 Nov 22;60(22):9184-9204. doi: 10.1021/acs.jmedchem.7b00941. Epub 2017 Nov 9.

16.

Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays.

Urban DJ, Martinez NJ, Davis MI, Brimacombe KR, Cheff DM, Lee TD, Henderson MJ, Titus SA, Pragani R, Rohde JM, Liu L, Fang Y, Karavadhi S, Shah P, Lee OW, Wang A, McIver A, Zheng H, Wang X, Xu X, Jadhav A, Simeonov A, Shen M, Boxer MB, Hall MD.

Sci Rep. 2017 Oct 6;7(1):12758. doi: 10.1038/s41598-017-12630-x.

17.

Development and validation of a real-time, reverse transcription PCR assay for rapid and low-cost genotyping of hepatitis C virus genotypes 1a, 1b, 2, and 3a.

Olmstead AD, Lee TD, Chow R, Gunadasa K, Auk B, Krajden M, Jassem AN.

J Virol Methods. 2017 Jun;244:17-22. doi: 10.1016/j.jviromet.2017.02.009. Epub 2017 Feb 20.

PMID:
28219761
18.
19.

mcr-1-Positive Colistin-Resistant Escherichia coli in Traveler Returning to Canada from China.

Payne M, Croxen MA, Lee TD, Mayson B, Champagne S, Leung V, Bariso S, Hoang L, Lowe C.

Emerg Infect Dis. 2016 Sep;22(9):1673-5. doi: 10.3201/eid2209.160177. No abstract available.

20.

Donor-Specific Antibodies Are Produced Locally in Ectopic Lymphoid Structures in Cardiac Allografts.

Huibers MM, Gareau AJ, Beerthuijzen JM, Siera-de Koning E, van Kuik J, Kamburova EG, Vink A, de Jonge N, Lee TD, Otten HG, de Weger RA.

Am J Transplant. 2017 Jan;17(1):246-254. doi: 10.1111/ajt.13969. Epub 2016 Aug 18.

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