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Items: 1 to 20 of 49


Measuring biological age in mice using differential mass spectrometry.

Bell-Temin H, Yousefzadeh MJ, Bondarenko A, Quarles E, Jones-Laughner J, Robbins PD, Ladiges W, Niedernhofer LJ, Yates NA.

Aging (Albany NY). 2019 Feb 11. doi: 10.18632/aging.101810. [Epub ahead of print]


Modeling Alzheimer's disease in progeria mice. An age-related concept.

Sharma K, Darvas M, Keene CD, Niedernhofer LJ, Ladiges W.

Pathobiol Aging Age Relat Dis. 2018 Oct 4;8(1):1524815. doi: 10.1080/20010001.2018.1524815. eCollection 2018.


Chronic oral rapamycin decreases adiposity, hepatic triglycerides and insulin resistance in male mice fed a diet high in sucrose and saturated fat.

den Hartigh LJ, Goodspeed L, Wang SA, Kenerson HL, Omer M, O'Brien KD, Ladiges W, Yeung R, Subramanian S.

Exp Physiol. 2018 Nov;103(11):1469-1480. doi: 10.1113/EP087207. Epub 2018 Sep 13.


Testing drug combinations to slow aging.

Ladiges W, Liggitt D.

Pathobiol Aging Age Relat Dis. 2017 Nov 23;8(1):1407203. doi: 10.1080/20010001.2017.1407203. eCollection 2018. No abstract available.


The potential use of physical resilience to predict healthy aging.

Schorr A, Carter C, Ladiges W.

Pathobiol Aging Age Relat Dis. 2017 Nov 21;8(1):1403844. doi: 10.1080/20010001.2017.1403844. eCollection 2018. Review.


The emerging role of geropathology in preclinical aging studies.

Ladiges W.

Pathobiol Aging Age Relat Dis. 2017 Mar 21;7(1):1304005. doi: 10.1080/20010001.2017.1304005. eCollection 2017. No abstract available.


Mitochondrial-Targeted Catalase Protects Against High-Fat Diet-Induced Muscle Insulin Resistance by Decreasing Intramuscular Lipid Accumulation.

Lee HY, Lee JS, Alves T, Ladiges W, Rabinovitch PS, Jurczak MJ, Choi CS, Shulman GI, Samuel VT.

Diabetes. 2017 Aug;66(8):2072-2081. doi: 10.2337/db16-1334. Epub 2017 May 5.


Chronic low-level exposure to the common seafood toxin domoic acid causes cognitive deficits in mice.

Lefebvre KA, Kendrick PS, Ladiges W, Hiolski EM, Ferriss BE, Smith DR, Marcinek DJ.

Harmful Algae. 2017 Apr;64:20-29. doi: 10.1016/j.hal.2017.03.003. Epub 2017 Mar 27.


A New Preclinical Paradigm for Testing Anti-Aging Therapeutics.

Ladiges W, Snyder JM, Wilkinson E, Imai DM, Snider T, Ge X, Ciol M, Pettan-Brewer C, Pillai SPS, Morton J, Quarles E, Rabinovitch P, Niedernhofer L, Liggitt D.

J Gerontol A Biol Sci Med Sci. 2017 Jun 1;72(6):760-762. doi: 10.1093/gerona/glx019.


Self-motivated and stress-response performance assays in mice are age-dependent.

Ge X, Ciol MA, Pettan-Brewer C, Goh J, Rabinovitch P, Ladiges W.

Exp Gerontol. 2017 May;91:1-4. doi: 10.1016/j.exger.2017.02.001. Epub 2017 Feb 8.


Molecular pathology endpoints useful for aging studies.

Niedernhofer LJ, Kirkland JL, Ladiges W.

Ageing Res Rev. 2017 May;35:241-249. doi: 10.1016/j.arr.2016.09.012. Epub 2016 Oct 6. Review.


Grip strength is potentially an early indicator of age-related decline in mice.

Ge X, Cho A, Ciol MA, Pettan-Brewer C, Snyder J, Rabinovitch P, Ladiges W.

Pathobiol Aging Age Relat Dis. 2016 Sep 8;6:32981. doi: 10.3402/pba.v6.32981. eCollection 2016. Erratum in: Pathobiol Aging Age Relat Dis. 2016 Oct 24;6:33718.


Neuropathological assessment and validation of mouse models for Alzheimer's disease: applying NIA-AA guidelines.

Keene CD, Darvas M, Kraemer B, Liggitt D, Sigurdson C, Ladiges W.

Pathobiol Aging Age Relat Dis. 2016 Jun 16;6:32397. doi: 10.3402/pba.v6.32397. eCollection 2016.


Application of the microfluidic-assisted replication track analysis to measure DNA repair in human and mouse cells.

Welcsh P, Kehrli K, Lazarchuk P, Ladiges W, Sidorova J.

Methods. 2016 Oct 1;108:99-110. doi: 10.1016/j.ymeth.2016.04.029. Epub 2016 Apr 26.


Pathology assessment is necessary to validate translational endpoints in preclinical aging studies.

Ladiges W.

Pathobiol Aging Age Relat Dis. 2016 Mar 23;6:31478. doi: 10.3402/pba.v6.31478. eCollection 2016.


Voluntary Wheel Running in Mice.

Goh J, Ladiges W.

Curr Protoc Mouse Biol. 2015 Dec 2;5(4):283-90. doi: 10.1002/9780470942390.mo140295.


The Geropathology Research Network: An Interdisciplinary Approach for Integrating Pathology Into Research on Aging.

Ladiges W, Ikeno Y, Niedernhofer L, McIndoe RA, Ciol MA, Ritchey J, Liggitt D.

J Gerontol A Biol Sci Med Sci. 2016 Apr;71(4):431-4. doi: 10.1093/gerona/glv079. Epub 2015 Aug 4.


Geropathology Research Network Symposium 2015.

Ladiges W.

Pathobiol Aging Age Relat Dis. 2015 Jul 1;5:28866. doi: 10.3402/pba.v5.28866. eCollection 2015. No abstract available.


The quality control theory of aging.

Ladiges W.

Pathobiol Aging Age Relat Dis. 2014 May 23;4. doi: 10.3402/pba.v4.24835. eCollection 2014.


Decline in muscle strength and running endurance in klotho deficient C57BL/6 mice.

Phelps M, Pettan-Brewer C, Ladiges W, Yablonka-Reuveni Z.

Biogerontology. 2013 Dec;14(6):729-39. doi: 10.1007/s10522-013-9447-2. Epub 2013 Sep 13.

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