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Nutrition epidemiology of flavan-3-ols: The known unknowns.

Kuhnle GGC.

Mol Aspects Med. 2017 Nov 16. pii: S0098-2997(17)30075-4. doi: 10.1016/j.mam.2017.10.003. [Epub ahead of print] Review.


Association between urinary biomarkers of total sugars intake and measures of obesity in a cross-sectional study.

Campbell R, Tasevska N, Jackson KG, Sagi-Kiss V, di Paolo N, Mindell JS, Lister SJ, Khaw KT, Kuhnle GGC.

PLoS One. 2017 Jul 19;12(7):e0179508. doi: 10.1371/journal.pone.0179508. eCollection 2017.


Sulfate, nitrate and blood pressure - An EPIC interaction between sulfur and nitrogen.

Kuhnle GG, Luben R, Khaw KT, Feelisch M.

Pharmacol Res. 2017 Aug;122:127-129. doi: 10.1016/j.phrs.2017.06.006. Epub 2017 Jun 10. Review.


The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine.

Cortese-Krott MM, Koning A, Kuhnle GGC, Nagy P, Bianco CL, Pasch A, Wink DA, Fukuto JM, Jackson AA, van Goor H, Olson KR, Feelisch M.

Antioxid Redox Signal. 2017 Oct 1;27(10):684-712. doi: 10.1089/ars.2017.7083. Epub 2017 Jun 6.


Red Wine and Pomegranate Extracts Suppress Cured Meat Promotion of Colonic Mucin-Depleted Foci in Carcinogen-Induced Rats.

Bastide NM, Naud N, Nassy G, Vendeuvre JL, Taché S, Guéraud F, Hobbs DA, Kuhnle GG, Corpet DE, Pierre FH.

Nutr Cancer. 2017 Feb-Mar;69(2):289-298. doi: 10.1080/01635581.2017.1263745. Epub 2017 Jan 17.


Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study.

Velmurugan S, Gan JM, Rathod KS, Khambata RS, Ghosh SM, Hartley A, Van Eijl S, Sagi-Kiss V, Chowdhury TA, Curtis M, Kuhnle GG, Wade WG, Ahluwalia A.

Am J Clin Nutr. 2016 Jan;103(1):25-38. doi: 10.3945/ajcn.115.116244. Epub 2015 Nov 25.


Cocoa flavanol intake improves endothelial function and Framingham Risk Score in healthy men and women: a randomised, controlled, double-masked trial: the Flaviola Health Study.

Sansone R, Rodriguez-Mateos A, Heuel J, Falk D, Schuler D, Wagstaff R, Kuhnle GG, Spencer JP, Schroeter H, Merx MW, Kelm M, Heiss C; Flaviola Consortium, European Union 7th Framework Program.

Br J Nutr. 2015 Oct 28;114(8):1246-55. doi: 10.1017/S0007114515002822. Epub 2015 Sep 9.


Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl.

Cortese-Krott MM, Kuhnle GG, Dyson A, Fernandez BO, Grman M, DuMond JF, Barrow MP, McLeod G, Nakagawa H, Ondrias K, Nagy P, King SB, Saavedra JE, Keefer LK, Singer M, Kelm M, Butler AR, Feelisch M.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):E4651-60. doi: 10.1073/pnas.1509277112. Epub 2015 Jul 29.


Impact of cocoa flavanol intake on age-dependent vascular stiffness in healthy men: a randomized, controlled, double-masked trial.

Heiss C, Sansone R, Karimi H, Krabbe M, Schuler D, Rodriguez-Mateos A, Kraemer T, Cortese-Krott MM, Kuhnle GG, Spencer JP, Schroeter H, Merx MW, Kelm M; FLAVIOLA Consortium, European Union 7th Framework Program.

Age (Dordr). 2015 Jun;37(3):9794. doi: 10.1007/s11357-015-9794-9. Epub 2015 May 27.


Flavonoid intake in European adults (18 to 64 years).

Vogiatzoglou A, Mulligan AA, Lentjes MA, Luben RN, Spencer JP, Schroeter H, Khaw KT, Kuhnle GG.

PLoS One. 2015 May 26;10(5):e0128132. doi: 10.1371/journal.pone.0128132. eCollection 2015.


Associations between flavan-3-ol intake and CVD risk in the Norfolk cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk).

Vogiatzoglou A, Mulligan AA, Bhaniani A, Lentjes MAH, McTaggart A, Luben RN, Heiss C, Kelm M, Merx MW, Spencer JPE, Schroeter H, Khaw KT, Kuhnle GGC.

Free Radic Biol Med. 2015 Jul;84:1-10. doi: 10.1016/j.freeradbiomed.2015.03.005. Epub 2015 Mar 17.


Reply to KJ Petzke.

Forouhi NG, Kuhnle GG, Patel PS, O'Connell TC.

Am J Clin Nutr. 2015 Mar;101(3):688. doi: 10.3945/ajcn.114.103309. No abstract available.


Association between sucrose intake and risk of overweight and obesity in a prospective sub-cohort of the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk).

Kuhnle GG, Tasevska N, Lentjes MA, Griffin JL, Sims MA, Richardson L, Aspinall SM, Mulligan AA, Luben RN, Khaw KT.

Public Health Nutr. 2015 Oct;18(15):2815-24. doi: 10.1017/S1368980015000300. Epub 2015 Feb 23.


A central role for heme iron in colon carcinogenesis associated with red meat intake.

Bastide NM, Chenni F, Audebert M, Santarelli RL, Taché S, Naud N, Baradat M, Jouanin I, Surya R, Hobbs DA, Kuhnle GG, Raymond-Letron I, Gueraud F, Corpet DE, Pierre FH.

Cancer Res. 2015 Mar 1;75(5):870-9. doi: 10.1158/0008-5472.CAN-14-2554. Epub 2015 Jan 15.


Serum carbon and nitrogen stable isotopes as potential biomarkers of dietary intake and their relation with incident type 2 diabetes: the EPIC-Norfolk study.

Patel PS, Cooper AJ, O'Connell TC, Kuhnle GG, Kneale CK, Mulligan AM, Luben RN, Brage S, Khaw KT, Wareham NJ, Forouhi NG.

Am J Clin Nutr. 2014 Aug;100(2):708-18. doi: 10.3945/ajcn.113.068577. Epub 2014 Jul 2.


O⁶-carboxymethylguanine DNA adduct formation and lipid peroxidation upon in vitro gastrointestinal digestion of haem-rich meat.

Vanden Bussche J, Hemeryck LY, Van Hecke T, Kuhnle GG, Pasmans F, Moore SA, Van de Wiele T, De Smet S, Vanhaecke L.

Mol Nutr Food Res. 2014 Sep;58(9):1883-96. doi: 10.1002/mnfr.201400078. Epub 2014 Jul 2.


Assessment of the dietary intake of total flavan-3-ols, monomeric flavan-3-ols, proanthocyanidins and theaflavins in the European Union.

Vogiatzoglou A, Mulligan AA, Luben RN, Lentjes MA, Heiss C, Kelm M, Merx MW, Spencer JP, Schroeter H, Kuhnle GG.

Br J Nutr. 2014 Apr 28;111(8):1463-73. doi: 10.1017/S0007114513003930. Epub 2013 Dec 13.


Estimated dietary intakes and sources of flavanols in the German population (German National Nutrition Survey II).

Vogiatzoglou A, Heuer T, Mulligan AA, Lentjes MA, Luben RN, Kuhnle GG.

Eur J Nutr. 2014;53(2):635-43. doi: 10.1007/s00394-013-0572-0. Epub 2013 Aug 6.


The diet-body offset in human nitrogen isotopic values: a controlled dietary study.

O'Connell TC, Kneale CJ, Tasevska N, Kuhnle GG.

Am J Phys Anthropol. 2012 Nov;149(3):426-34. doi: 10.1002/ajpa.22140. Epub 2012 Oct 5.


A multilevel analytical approach for detection and visualization of intracellular NO production and nitrosation events using diaminofluoresceins.

Cortese-Krott MM, Rodriguez-Mateos A, Kuhnle GG, Brown G, Feelisch M, Kelm M.

Free Radic Biol Med. 2012 Dec 1;53(11):2146-58. doi: 10.1016/j.freeradbiomed.2012.09.008. Epub 2012 Sep 28.


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