Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 45

1.

Regeneration of Cochlear Hair Cells and Hearing Recovery through Hes1 Modulation with siRNA Nanoparticles in Adult Guinea Pigs.

Du X, Cai Q, West MB, Youm I, Huang X, Li W, Cheng W, Nakmali D, Ewert DL, Kopke RD.

Mol Ther. 2018 May 2;26(5):1313-1326. doi: 10.1016/j.ymthe.2018.03.004. Epub 2018 Mar 10.

PMID:
29680697
2.

HPN-07, a free radical spin trapping agent, protects against functional, cellular and electrophysiological changes in the cochlea induced by acute acoustic trauma.

Ewert D, Hu N, Du X, Li W, West MB, Choi CH, Floyd R, Kopke RD.

PLoS One. 2017 Aug 23;12(8):e0183089. doi: 10.1371/journal.pone.0183089. eCollection 2017.

3.

siRNA-loaded biodegradable nanocarriers for therapeutic MAPK1 silencing against cisplatin-induced ototoxicity.

Youm I, West MB, Li W, Du X, Ewert DL, Kopke RD.

Int J Pharm. 2017 Aug 7;528(1-2):611-623. doi: 10.1016/j.ijpharm.2017.06.035. Epub 2017 Jun 13.

PMID:
28627458
4.

Antioxidants reduce neurodegeneration and accumulation of pathologic Tau proteins in the auditory system after blast exposure.

Du X, West MB, Cai Q, Cheng W, Ewert DL, Li W, Floyd RA, Kopke RD.

Free Radic Biol Med. 2017 Jul;108:627-643. doi: 10.1016/j.freeradbiomed.2017.04.343. Epub 2017 Apr 22.

PMID:
28438658
5.

Ameliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain Injury.

Du X, West MB, Cheng W, Ewert DL, Li W, Saunders D, Towner RA, Floyd RA, Kopke RD.

Oxid Med Cell Longev. 2016;2016:4159357. doi: 10.1155/2016/4159357. Epub 2015 Dec 16.

6.

Antioxidants reduce cellular and functional changes induced by intense noise in the inner ear and cochlear nucleus.

Lu J, Li W, Du X, Ewert DL, West MB, Stewart C, Floyd RA, Kopke RD.

J Assoc Res Otolaryngol. 2014 Jun;15(3):353-72. doi: 10.1007/s10162-014-0441-4. Epub 2014 Feb 5. Erratum in: J Assoc Res Otolaryngol. 2014 Jun;15(3):373-4.

7.

Effects of antioxidant treatment on blast-induced brain injury.

Du X, Ewert DL, Cheng W, West MB, Lu J, Li W, Floyd RA, Kopke RD.

PLoS One. 2013 Nov 5;8(11):e80138. doi: 10.1371/journal.pone.0080138. eCollection 2013.

8.

Therapeutic effects of orally administrated antioxidant drugs on acute noise-induced hearing loss.

Choi CH, Du X, Floyd RA, Kopke RD.

Free Radic Res. 2014 Mar;48(3):264-72. doi: 10.3109/10715762.2013.861599. Epub 2013 Nov 28.

PMID:
24182331
9.

Regeneration of mammalian cochlear and vestibular hair cells through Hes1/Hes5 modulation with siRNA.

Du X, Li W, Gao X, West MB, Saltzman WM, Cheng CJ, Stewart C, Zheng J, Cheng W, Kopke RD.

Hear Res. 2013 Oct;304:91-110. doi: 10.1016/j.heares.2013.06.011. Epub 2013 Jul 9.

10.

Magnetic targeted delivery of dexamethasone acetate across the round window membrane in guinea pigs.

Du X, Chen K, Kuriyavar S, Kopke RD, Grady BP, Bourne DH, Li W, Dormer KJ.

Otol Neurotol. 2013 Jan;34(1):41-7. doi: 10.1097/MAO.0b013e318277a40e.

11.

Selective degeneration of synapses in the dorsal cochlear nucleus of chinchilla following acoustic trauma and effects of antioxidant treatment.

Du X, Chen K, Choi CH, Li W, Cheng W, Stewart C, Hu N, Floyd RA, Kopke RD.

Hear Res. 2012 Jan;283(1-2):1-13. doi: 10.1016/j.heares.2011.11.013. Epub 2011 Dec 9.

PMID:
22178982
12.

Reduced formation of oxidative stress biomarkers and migration of mononuclear phagocytes in the cochleae of chinchilla after antioxidant treatment in acute acoustic trauma.

Du X, Choi CH, Chen K, Cheng W, Floyd RA, Kopke RD.

Int J Otolaryngol. 2011;2011:612690. doi: 10.1155/2011/612690. Epub 2011 Sep 25.

13.

Effects of delayed and extended antioxidant treatment on acute acoustic trauma.

Choi CH, Chen K, Du X, Floyd RA, Kopke RD.

Free Radic Res. 2011 Oct;45(10):1162-72. doi: 10.3109/10715762.2011.605360. Epub 2011 Aug 10.

PMID:
21756051
14.

Low-dose D-methionine and N-acetyl-L-cysteine for protection from permanent noise-induced hearing loss in chinchillas.

Clifford RE, Coleman JK, Balough BJ, Liu J, Kopke RD, Jackson RL.

Otolaryngol Head Neck Surg. 2011 Dec;145(6):999-1006. doi: 10.1177/0194599811414496. Epub 2011 Jul 12.

PMID:
21750343
15.

Detecting incipient inner-ear damage from impulse noise with otoacoustic emissions.

Marshall L, Lapsley Miller JA, Heller LM, Wolgemuth KS, Hughes LM, Smith SD, Kopke RD.

J Acoust Soc Am. 2009 Feb;125(2):995-1013. doi: 10.1121/1.3050304.

PMID:
19206875
16.

Nitrones as therapeutics.

Floyd RA, Kopke RD, Choi CH, Foster SB, Doblas S, Towner RA.

Free Radic Biol Med. 2008 Nov 15;45(10):1361-74. doi: 10.1016/j.freeradbiomed.2008.08.017. Epub 2008 Aug 29. Review.

17.

Effectiveness of 4-hydroxy phenyl N-tert-butylnitrone (4-OHPBN) alone and in combination with other antioxidant drugs in the treatment of acute acoustic trauma in chinchilla.

Choi CH, Chen K, Vasquez-Weldon A, Jackson RL, Floyd RA, Kopke RD.

Free Radic Biol Med. 2008 May 1;44(9):1772-84. doi: 10.1016/j.freeradbiomed.2008.02.005. Epub 2008 Feb 20.

PMID:
18328271
18.

Distribution of PLGA nanoparticles in chinchilla cochleae.

Ge X, Jackson RL, Liu J, Harper EA, Hoffer ME, Wassel RA, Dormer KJ, Kopke RD, Balough BJ.

Otolaryngol Head Neck Surg. 2007 Oct;137(4):619-23.

PMID:
17903580
19.

Noise protection with N-acetyl-l-cysteine (NAC) using a variety of noise exposures, NAC doses, and routes of administration.

Bielefeld EC, Kopke RD, Jackson RL, Coleman JK, Liu J, Henderson D.

Acta Otolaryngol. 2007 Sep;127(9):914-9.

PMID:
17712668
20.

Magnetic characterization of superparamagnetic nanoparticles pulled through model membranes.

Barnes AL, Wassel RA, Mondalek F, Chen K, Dormer KJ, Kopke RD.

Biomagn Res Technol. 2007 Jan 4;5:1.

Supplemental Content

Loading ...
Support Center