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Items: 1 to 20 of 125

1.

Evaluation of life cycle defective Adenovirus mutants for production of Adeno-Associated Virus vectors.

Krüger-Haag A, Lehmann C, Schmidt E, Sonntag F, Hörer M, Kochanek S.

J Gene Med. 2019 Apr 30:e3094. doi: 10.1002/jgm.3094. [Epub ahead of print]

PMID:
31037799
2.

JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin.

Singh K, Camera E, Krug L, Basu A, Pandey RK, Munir S, Wlaschek M, Kochanek S, Schorpp-Kistner M, Picardo M, Angel P, Niemann C, Maity P, Scharffetter-Kochanek K.

Nat Commun. 2018 Aug 24;9(1):3425. doi: 10.1038/s41467-018-05726-z.

3.

Recent advances in gene-enhanced bone tissue engineering.

Betz VM, Kochanek S, Rammelt S, Müller PE, Betz OB, Messmer C.

J Gene Med. 2018 Jun;20(6):e3018. doi: 10.1002/jgm.3018. Epub 2018 May 9. Review.

PMID:
29601661
4.

Age-related pathology after adenoviral overexpression of the leucine-rich repeat kinase 2 in the mouse striatum.

Kritzinger A, Ferger B, Gillardon F, Stierstorfer B, Birk G, Kochanek S, Ciossek T.

Neurobiol Aging. 2018 Jun;66:97-111. doi: 10.1016/j.neurobiolaging.2018.02.008. Epub 2018 Feb 16.

5.

The cryo-electron microscopy structure of huntingtin.

Guo Q, Bin Huang, Cheng J, Seefelder M, Engler T, Pfeifer G, Oeckl P, Otto M, Moser F, Maurer M, Pautsch A, Baumeister W, Fernández-Busnadiego R, Kochanek S.

Nature. 2018 Mar 1;555(7694):117-120. doi: 10.1038/nature25502. Epub 2018 Feb 21.

6.

Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction.

Singh K, Krug L, Basu A, Meyer P, Treiber N, Vander Beken S, Wlaschek M, Kochanek S, Bloch W, Geiger H, Maity P, Scharffetter-Kochanek K.

Stem Cells. 2017 Jul;35(7):1704-1718. doi: 10.1002/stem.2629. Epub 2017 May 2.

7.

Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration.

Farsam V, Basu A, Gatzka M, Treiber N, Schneider LA, Mulaw MA, Lucas T, Kochanek S, Dummer R, Levesque MP, Wlaschek M, Scharffetter-Kochanek K.

Oncotarget. 2016 Dec 13;7(50):83554-83569. doi: 10.18632/oncotarget.13446.

8.

miR-483 is a self-regulating microRNA and can activate its own expression via USF1 in HeLa cells.

Emmerling VV, Fischer S, Kleemann M, Handrick R, Kochanek S, Otte K.

Int J Biochem Cell Biol. 2016 Nov;80:81-86. doi: 10.1016/j.biocel.2016.09.022. Epub 2016 Sep 28.

PMID:
27693430
9.

Temperature-sensitive miR-483 is a conserved regulator of recombinant protein and viral vector production in mammalian cells.

Emmerling VV, Fischer S, Stiefel F, Holzmann K, Handrick R, Hesse F, Hörer M, Kochanek S, Otte K.

Biotechnol Bioeng. 2016 Apr;113(4):830-41. doi: 10.1002/bit.25853. Epub 2015 Oct 20.

PMID:
26461143
10.

Rational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells.

Emmerling VV, Pegel A, Milian EG, Venereo-Sanchez A, Kunz M, Wegele J, Kamen AA, Kochanek S, Hoerer M.

Biotechnol J. 2016 Feb;11(2):290-7. doi: 10.1002/biot.201500176. Epub 2015 Sep 24.

PMID:
26284700
11.

Design and activity of AP endonuclease-1 inhibitors.

Feng Z, Kochanek S, Close D, Wang L, Srinivasan A, Almehizia AA, Iyer P, Xie XQ, Johnston PA, Gold B.

J Chem Biol. 2015 Apr 19;8(3):79-93. doi: 10.1007/s12154-015-0131-7. eCollection 2015 Jul.

12.

Human amniocyte-derived cells are a promising cell host for adenoviral vector production under serum-free conditions.

Silva AC, Simão D, Küppers C, Lucas T, Sousa MF, Cruz P, Carrondo MJ, Kochanek S, Alves PM.

Biotechnol J. 2015 May;10(5):760-71. doi: 10.1002/biot.201400765.

PMID:
25943527
13.

CD169+ macrophages are sufficient for priming of CTLs with specificities left out by cross-priming dendritic cells.

Bernhard CA, Ried C, Kochanek S, Brocker T.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5461-6. doi: 10.1073/pnas.1423356112. Epub 2015 Apr 14.

14.

Scalable production in human cells and biochemical characterization of full-length normal and mutant huntingtin.

Huang B, Lucas T, Kueppers C, Dong X, Krause M, Bepperling A, Buchner J, Voshol H, Weiss A, Gerrits B, Kochanek S.

PLoS One. 2015 Mar 23;10(3):e0121055. doi: 10.1371/journal.pone.0121055. eCollection 2015.

15.

Hexon modification to improve the activity of oncolytic adenovirus vectors against neoplastic and stromal cells in pancreatic cancer.

Lucas T, Benihoud K, Vigant F, Schmidt CQ, Wortmann A, Bachem MG, Simmet T, Kochanek S.

PLoS One. 2015 Feb 18;10(2):e0117254. doi: 10.1371/journal.pone.0117254. eCollection 2015. Erratum in: PLoS One. 2015;10(4):e0123844. Schmidt, Christoph Q Andreas [corrected to Schmidt, Christoph Q]; Wortmann, Andreas [added].

16.

Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN.

Singh K, Maity P, Krug L, Meyer P, Treiber N, Lucas T, Basu A, Kochanek S, Wlaschek M, Geiger H, Scharffetter-Kochanek K.

EMBO Mol Med. 2015 Jan;7(1):59-77. doi: 10.15252/emmm.201404082.

17.

Pancreatic transduction by helper-dependent adenoviral vectors via intraductal delivery.

Morró M, Teichenne J, Jimenez V, Kratzer R, Marletta S, Maggioni L, Mallol C, Ruberte J, Kochanek S, Bosch F, Ayuso E.

Hum Gene Ther. 2014 Sep;25(9):824-36. doi: 10.1089/hum.2013.182.

18.

Traceless bioresponsive shielding of adenovirus hexon with HPMA copolymers maintains transduction capacity in vitro and in vivo.

Prill JM, Subr V, Pasquarelli N, Engler T, Hoffmeister A, Kochanek S, Ulbrich K, Kreppel F.

PLoS One. 2014 Jan 27;9(1):e82716. doi: 10.1371/journal.pone.0082716. eCollection 2014.

19.

The transcription factor serum response factor stimulates axon regeneration through cytoplasmic localization and cofilin interaction.

Stern S, Haverkamp S, Sinske D, Tedeschi A, Naumann U, Di Giovanni S, Kochanek S, Nordheim A, Knöll B.

J Neurosci. 2013 Nov 27;33(48):18836-48. doi: 10.1523/JNEUROSCI.3029-13.2013.

20.

Foamy virus-adenovirus hybrid vectors for gene therapy of the arthritides.

Weber C, Armbruster N, Scheller C, Kreppel F, Kochanek S, Rethwilm A, Steinert AF.

J Gene Med. 2013 Mar-Apr;15(3-4):155-67. doi: 10.1002/jgm.2705.

PMID:
23554302

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