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Items: 1 to 20 of 47


The Neutral Theory in Light of Natural Selection.

Kern AD, Hahn MW.

Mol Biol Evol. 2018 Jun 1;35(6):1366-1371. doi: 10.1093/molbev/msy092.


Combining population genomics and fitness QTLs to identify the genetics of local adaptation in Arabidopsis thaliana.

Price N, Moyers BT, Lopez L, Lasky JR, Monroe JG, Mullen JL, Oakley CG, Lin J, Ă…gren J, Schrider DR, Kern AD, McKay JK.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):5028-5033. doi: 10.1073/pnas.1719998115. Epub 2018 Apr 23.


Supervised machine learning reveals introgressed loci in the genomes of Drosophila simulans and D. sechellia.

Schrider DR, Ayroles J, Matute DR, Kern AD.

PLoS Genet. 2018 Apr 23;14(4):e1007341. doi: 10.1371/journal.pgen.1007341. eCollection 2018 Apr.


diploS/HIC: An Updated Approach to Classifying Selective Sweeps.

Kern AD, Schrider DR.

G3 (Bethesda). 2018 May 31;8(6):1959-1970. doi: 10.1534/g3.118.200262.


Supervised Machine Learning for Population Genetics: A New Paradigm.

Schrider DR, Kern AD.

Trends Genet. 2018 Apr;34(4):301-312. doi: 10.1016/j.tig.2017.12.005. Epub 2018 Jan 10. Review.


Exact Calculation of the Joint Allele Frequency Spectrum for Isolation with Migration Models.

Kern AD, Hey J.

Genetics. 2017 Sep;207(1):241-253. doi: 10.1534/genetics.116.194019. Epub 2017 Jul 10.


Soft Sweeps Are the Dominant Mode of Adaptation in the Human Genome.

Schrider DR, Kern AD.

Mol Biol Evol. 2017 Aug 1;34(8):1863-1877. doi: 10.1093/molbev/msx154.


Effects of Linked Selective Sweeps on Demographic Inference and Model Selection.

Schrider DR, Shanku AG, Kern AD.

Genetics. 2016 Nov;204(3):1207-1223. doi: 10.1534/genetics.116.190223. Epub 2016 Sep 7.


Discoal: flexible coalescent simulations with selection.

Kern AD, Schrider DR.

Bioinformatics. 2016 Dec 15;32(24):3839-3841. Epub 2016 Aug 24.


S/HIC: Robust Identification of Soft and Hard Sweeps Using Machine Learning.

Schrider DR, Kern AD.

PLoS Genet. 2016 Mar 15;12(3):e1005928. doi: 10.1371/journal.pgen.1005928. eCollection 2016 Mar.


Inferring Selective Constraint from Population Genomic Data Suggests Recent Regulatory Turnover in the Human Brain.

Schrider DR, Kern AD.

Genome Biol Evol. 2015 Nov 19;7(12):3511-28. doi: 10.1093/gbe/evv228.


Myristoylated CIL-7 regulates ciliary extracellular vesicle biogenesis.

Maguire JE, Silva M, Nguyen KC, Hellen E, Kern AD, Hall DH, Barr MM.

Mol Biol Cell. 2015 Aug 1;26(15):2823-32. doi: 10.1091/mbc.E15-01-0009. Epub 2015 Jun 3.


Soft shoulders ahead: spurious signatures of soft and partial selective sweeps result from linked hard sweeps.

Schrider DR, Mendes FK, Hahn MW, Kern AD.

Genetics. 2015 May;200(1):267-84. doi: 10.1534/genetics.115.174912. Epub 2015 Feb 25.


The role of DNA insertions in phenotypic differentiation between humans and other primates.

Hellen EH, Kern AD.

Genome Biol Evol. 2015 Jan 28;7(4):1168-78. doi: 10.1093/gbe/evv012.


Highly constrained intergenic Drosophila ultraconserved elements are candidate ncRNAs.

Kern AD, Barbash DA, Chang Mell J, Hupalo D, Jensen A.

Genome Biol Evol. 2015 Jan 23;7(3):689-98. doi: 10.1093/gbe/evv011.


Discovering functional DNA elements using population genomic information: a proof of concept using human mtDNA.

Schrider DR, Kern AD.

Genome Biol Evol. 2014 Jun 9;6(7):1542-8. doi: 10.1093/gbe/evu116.


Parallel geographic variation in Drosophila melanogaster.

Reinhardt JA, Kolaczkowski B, Jones CD, Begun DJ, Kern AD.

Genetics. 2014 May;197(1):361-73. doi: 10.1534/genetics.114.161463. Epub 2014 Mar 7.


Conservation and functional element discovery in 20 angiosperm plant genomes.

Hupalo D, Kern AD.

Mol Biol Evol. 2013 Jul;30(7):1729-44. doi: 10.1093/molbev/mst082. Epub 2013 May 2.


Functional Annotation and Comparative Analysis of a Zygopteran Transcriptome.

Shanku AG, McPeek MA, Kern AD.

G3 (Bethesda). 2013 Apr 9;3(4):763-770. doi: 10.1534/g3.113.005637.

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