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Items: 1 to 20 of 277

1.

DNA damage in lymphocytes of patients suffering from complex traumatization.

Bergholz LM, Subic-Wrana C, Heylmann D, Beutel ME, Wiltink J, Kaina B.

DNA Repair (Amst). 2017 Apr;52:103-109. doi: 10.1016/j.dnarep.2017.02.006.

PMID:
28254426
2.

Chloroethylating nitrosoureas in cancer therapy: DNA damage, repair and cell death signaling.

Nikolova T, Roos WP, Krämer OH, Strik HM, Kaina B.

Biochim Biophys Acta. 2017 Jan 29;1868(1):29-39. doi: 10.1016/j.bbcan.2017.01.004. [Epub ahead of print] Review.

PMID:
28143714
3.

Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome.

Reich TR, Switzeny OJ, Renovanz M, Sommer C, Kaina B, Christmann M, Tomicic MT.

Oncotarget. 2017 Jan 19. doi: 10.18632/oncotarget.14748. [Epub ahead of print]

4.

Death of Monocytes through Oxidative Burst of Macrophages and Neutrophils: Killing in Trans.

Ponath V, Kaina B.

PLoS One. 2017 Jan 18;12(1):e0170347. doi: 10.1371/journal.pone.0170347.

5.

Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells.

Noack K, Mahendrarajah N, Hennig D, Schmidt L, Grebien F, Hildebrand D, Christmann M, Kaina B, Sellmer A, Mahboobi S, Kubatzky K, Heinzel T, Krämer OH.

Arch Toxicol. 2016 Nov 2. [Epub ahead of print]

PMID:
27807597
6.

Targeting Homologous Recombination by Pharmacological Inhibitors Enhances the Killing Response of Glioblastoma Cells Treated with Alkylating Drugs.

Berte N, Piée-Staffa A, Piecha N, Wang M, Borgmann K, Kaina B, Nikolova T.

Mol Cancer Ther. 2016 Nov;15(11):2665-2678.

PMID:
27474153
7.

Quantification of Radiation Biomarkers in Leukocytes of Breast Cancer Patients Treated with Different Modalities of 3D-CRT or IMRT.

Zahnreich S, Ebersberger A, Karle H, Kaina B, Schmidberger H.

Radiat Res. 2016 Nov;186(5):508-519.

PMID:
27788031
8.

Past, present and future of immunology in Mainz.

Waisman A, Hövelmeyer N, Diefenbach A, Schuppan D, Reddehase MJ, Kleinert H, Kaina B, Grabbe S, Galle PR, Theobald M, Zipp F, Sahin U, Türeci Ö, Kreiter S, Langguth P, Decker H, van Zandbergen G, Schild H.

Cell Immunol. 2016 Oct;308:1-6. doi: 10.1016/j.cellimm.2016.09.001. No abstract available.

PMID:
27719802
9.

Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations.

Christmann M, Boisseau C, Kitzinger R, Berac C, Allmann S, Sommer T, Aasland D, Kaina B, Tomicic MT.

Nucleic Acids Res. 2016 Dec 15;44(22):10727-10743.

10.

Impact of DNA repair on the dose-response of colorectal cancer formation induced by dietary carcinogens.

Fahrer J, Kaina B.

Food Chem Toxicol. 2016 Oct 6. pii: S0278-6915(16)30345-3. doi: 10.1016/j.fct.2016.09.029. [Epub ahead of print]

PMID:
27693244
11.

Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence.

Berte N, Lokan S, Eich M, Kim E, Kaina B.

Oncotarget. 2016 Oct 11;7(41):67235-67250. doi: 10.18632/oncotarget.11972.

12.

DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP.

Mimmler M, Peter S, Kraus A, Stroh S, Nikolova T, Seiwert N, Hasselwander S, Neitzel C, Haub J, Monien BH, Nicken P, Steinberg P, Shay JW, Kaina B, Fahrer J.

Nucleic Acids Res. 2016 Dec 1;44(21):10259-10276.

13.

Integrin αVβ3 silencing sensitizes malignant glioma cells to temozolomide by suppression of homologous recombination repair.

Christmann M, Diesler K, Majhen D, Steigerwald C, Berte N, Freund H, Stojanović N, Kaina B, Osmak M, Ambriović-Ristov A, Tomicic MT.

Oncotarget. 2016 Jul 28. doi: 10.18632/oncotarget.10897. [Epub ahead of print]

14.

Nitroglycerin induces DNA damage and vascular cell death in the setting of nitrate tolerance.

Mikhed Y, Fahrer J, Oelze M, Kröller-Schön S, Steven S, Welschof P, Zinßius E, Stamm P, Kashani F, Roohani S, Kress JM, Ullmann E, Tran LP, Schulz E, Epe B, Kaina B, Münzel T, Daiber A.

Basic Res Cardiol. 2016 Jul;111(4):52. doi: 10.1007/s00395-016-0571-4.

PMID:
27357950
15.

MGMT promoter methylation determined by HRM in comparison to MSP and pyrosequencing for predicting high-grade glioma response.

Switzeny OJ, Christmann M, Renovanz M, Giese A, Sommer C, Kaina B.

Clin Epigenetics. 2016 May 5;8:49. doi: 10.1186/s13148-016-0204-7.

16.

Enhanced Histone Deacetylase Activity in Malignant Melanoma Provokes RAD51 and FANCD2-Triggered Drug Resistance.

Krumm A, Barckhausen C, Kücük P, Tomaszowski KH, Loquai C, Fahrer J, Krämer OH, Kaina B, Roos WP.

Cancer Res. 2016 May 15;76(10):3067-77. doi: 10.1158/0008-5472.CAN-15-2680.

PMID:
26980768
17.

The γH2AX DNA damage assay from a drop of blood.

Heylmann D, Kaina B.

Sci Rep. 2016 Mar 4;6:22682. doi: 10.1038/srep22682.

18.

The Brassica-derived phytochemical indolo[3,2-b]carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation.

Faust D, Nikolova T, Wätjen W, Kaina B, Dietrich C.

Arch Toxicol. 2017 Feb;91(2):967-982. doi: 10.1007/s00204-016-1672-4.

PMID:
26856715
19.

DNA damage and the balance between survival and death in cancer biology.

Roos WP, Thomas AD, Kaina B.

Nat Rev Cancer. 2016 Jan;16(1):20-33. doi: 10.1038/nrc.2015.2. Review.

PMID:
26678314
20.

Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM.

Tomicic MT, Meise R, Aasland D, Berte N, Kitzinger R, Krämer OH, Kaina B, Christmann M.

Oncotarget. 2015 Oct 20;6(32):33755-68. doi: 10.18632/oncotarget.5274.

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