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Items: 1 to 20 of 52


T-cell egress from the thymus: Should I stay or should I go?

James KD, Jenkinson WE, Anderson G.

J Leukoc Biol. 2018 Aug;104(2):275-284. doi: 10.1002/JLB.1MR1217-496R. Epub 2018 Feb 27. Review.


Potential role of the mitochondria as a target for the hepatotoxic effects of (-)-epigallocatechin-3-gallate in mice.

James KD, Kennett MJ, Lambert JD.

Food Chem Toxicol. 2018 Jan;111:302-309. doi: 10.1016/j.fct.2017.11.029. Epub 2017 Nov 22.


Redefining thymus medulla specialization for central tolerance.

Cosway EJ, Lucas B, James KD, Parnell SM, Carvalho-Gaspar M, White AJ, Tumanov AV, Jenkinson WE, Anderson G.

J Exp Med. 2017 Nov 6;214(11):3183-3195. doi: 10.1084/jem.20171000. Epub 2017 Aug 22.


In vitro activity of the novel echinocandin CD101 at pH 7 and 4 against Candida spp. isolates from patients with vulvovaginal candidiasis.

Boikov DA, Locke JB, James KD, Bartizal K, Sobel JD.

J Antimicrob Chemother. 2017 May 1;72(5):1355-1358. doi: 10.1093/jac/dkx008.


Pharmacokinetics of the Novel Echinocandin CD101 in Multiple Animal Species.

Ong V, James KD, Smith S, Krishnan BR.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e01626-16. doi: 10.1128/AAC.01626-16. Print 2017 Apr.


Structure-Activity Relationships of a Series of Echinocandins and the Discovery of CD101, a Highly Stable and Soluble Echinocandin with Distinctive Pharmacokinetic Properties.

James KD, Laudeman CP, Malkar NB, Krishnan R, Polowy K.

Antimicrob Agents Chemother. 2017 Jan 24;61(2). pii: e01541-16. doi: 10.1128/AAC.01541-16. Print 2017 Feb.


[Anatomical study of pelvic colon].

James YE, Tchangai B, Kassegne I, Keke K, James KD.

Morphologie. 2016 Dec;100(331):216-222. doi: 10.1016/j.morpho.2016.03.001. Epub 2016 May 20. French.


Preclinical Evaluation of the Stability, Safety, and Efficacy of CD101, a Novel Echinocandin.

Ong V, Hough G, Schlosser M, Bartizal K, Balkovec JM, James KD, Krishnan BR.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6872-6879. doi: 10.1128/AAC.00701-16. Print 2016 Nov.


Lymphotoxin β Receptor Controls T Cell Progenitor Entry to the Thymus.

Lucas B, James KD, Cosway EJ, Parnell SM, Tumanov AV, Ware CF, Jenkinson WE, Anderson G.

J Immunol. 2016 Oct 1;197(7):2665-72. doi: 10.4049/jimmunol.1601189. Epub 2016 Aug 22.


CD101, a novel echinocandin with exceptional stability properties and enhanced aqueous solubility.

Krishnan BR, James KD, Polowy K, Bryant BJ, Vaidya A, Smith S, Laudeman CP.

J Antibiot (Tokyo). 2017 Feb;70(2):130-135. doi: 10.1038/ja.2016.89. Epub 2016 Aug 10.


Control of the thymic medulla and its influence on αβT-cell development.

Lucas B, McCarthy NI, Baik S, Cosway E, James KD, Parnell SM, White AJ, Jenkinson WE, Anderson G.

Immunol Rev. 2016 May;271(1):23-37. doi: 10.1111/imr.12406. Review.


Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome.

Illingworth RS, Gruenewald-Schneider U, De Sousa D, Webb S, Merusi C, Kerr AR, James KD, Smith C, Walker R, Andrews R, Bird AP.

Nucleic Acids Res. 2015 Jan;43(2):732-44. doi: 10.1093/nar/gku1305. Epub 2015 Jan 8.


Hip pathology in Hutchinson-Gilford progeria syndrome: a report of two children.

Akhbari P, Jha S, James KD, Hinves BL, Buchanan JA.

J Pediatr Orthop B. 2012 Nov;21(6):563-6. doi: 10.1097/BPB.0b013e3283528ddd.


Orphan CpG islands identify numerous conserved promoters in the mammalian genome.

Illingworth RS, Gruenewald-Schneider U, Webb S, Kerr AR, James KD, Turner DJ, Smith C, Harrison DJ, Andrews R, Bird AP.

PLoS Genet. 2010 Sep 23;6(9):e1001134. doi: 10.1371/journal.pgen.1001134.


CpG islands influence chromatin structure via the CpG-binding protein Cfp1.

Thomson JP, Skene PJ, Selfridge J, Clouaire T, Guy J, Webb S, Kerr AR, Deaton A, Andrews R, James KD, Turner DJ, Illingworth R, Bird A.

Nature. 2010 Apr 15;464(7291):1082-6. doi: 10.1038/nature08924.


Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.

Skene PJ, Illingworth RS, Webb S, Kerr AR, James KD, Turner DJ, Andrews R, Bird AP.

Mol Cell. 2010 Feb 26;37(4):457-68. doi: 10.1016/j.molcel.2010.01.030.


FRT-seq: amplification-free, strand-specific transcriptome sequencing.

Mamanova L, Andrews RM, James KD, Sheridan EM, Ellis PD, Langford CF, Ost TW, Collins JE, Turner DJ.

Nat Methods. 2010 Feb;7(2):130-2. doi: 10.1038/nmeth.1417. Epub 2010 Jan 17.


A strand-specific RNA-Seq analysis of the transcriptome of the typhoid bacillus Salmonella typhi.

Perkins TT, Kingsley RA, Fookes MC, Gardner PP, James KD, Yu L, Assefa SA, He M, Croucher NJ, Pickard DJ, Maskell DJ, Parkhill J, Choudhary J, Thomson NR, Dougan G.

PLoS Genet. 2009 Jul;5(7):e1000569. doi: 10.1371/journal.pgen.1000569. Epub 2009 Jul 17.


Chronic actions of a novel oral B-type natriuretic peptide conjugate in normal dogs and acute actions in angiotensin II-mediated hypertension.

Cataliotti A, Chen HH, Schirger JA, Martin FL, Boerrigter G, Costello-Boerrigter LC, James KD, Polowy K, Miller MA, Malkar NB, Bailey KR, Burnett JC Jr.

Circulation. 2008 Oct 21;118(17):1729-36. doi: 10.1161/CIRCULATIONAHA.107.759241. Epub 2008 Oct 6.

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