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Items: 1 to 20 of 563

1.

One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation.

Jacobsen JT, Mesin L, Markoulaki S, Schiepers A, Cavazzoni CB, Bousbaine D, Jaenisch R, Victora GD.

J Exp Med. 2018 Sep 4. pii: jem.20172064. doi: 10.1084/jem.20172064. [Epub ahead of print]

PMID:
30181412
2.

Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections.

Muffat J, Li Y, Omer A, Durbin A, Bosch I, Bakiasi G, Richards E, Meyer A, Gehrke L, Jaenisch R.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):7117-7122. doi: 10.1073/pnas.1719266115. Epub 2018 Jun 18.

PMID:
29915057
3.

Building Capacity for a Global Genome Editing Observatory: Institutional Design.

Saha K, Hurlbut JB, Jasanoff S, Ahmed A, Appiah A, Bartholet E, Baylis F, Bennett G, Church G, Cohen IG, Daley G, Finneran K, Hurlbut W, Jaenisch R, Lwoff L, Kimes JP, Mills P, Moses J, Park BS, Parens E, Salzman R, Saxena A, Simmet H, Simoncelli T, Snead OC, Rajan KS, Truog RD, Williams P, Woopen C.

Trends Biotechnol. 2018 Aug;36(8):741-743. doi: 10.1016/j.tibtech.2018.04.008. Epub 2018 Jun 8.

PMID:
29891181
4.

Building Capacity for a Global Genome Editing Observatory: Conceptual Challenges.

Hurlbut JB, Jasanoff S, Saha K, Ahmed A, Appiah A, Bartholet E, Baylis F, Bennett G, Church G, Cohen IG, Daley G, Finneran K, Hurlbut W, Jaenisch R, Lwoff L, Kimes JP, Mills P, Moses J, Park BS, Parens E, Salzman R, Saxena A, Simmet H, Simoncelli T, Snead OC, Rajan KS, Truog RD, Williams P, Woopen C.

Trends Biotechnol. 2018 Jul;36(7):639-641. doi: 10.1016/j.tibtech.2018.04.009. Epub 2018 Jun 2.

PMID:
29871776
5.

Matched Developmental Timing of Donor Cells with the Host Is Crucial for Chimera Formation.

Cohen MA, Markoulaki S, Jaenisch R.

Stem Cell Reports. 2018 May 8;10(5):1445-1452. doi: 10.1016/j.stemcr.2018.03.004. Epub 2018 Mar 29.

6.

Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas.

Ma H, Wert KJ, Shvartsman D, Melton DA, Jaenisch R.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3924-3929. doi: 10.1073/pnas.1702059115. Epub 2018 Mar 29.

PMID:
29599125
7.

Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors.

Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, Haggarty SJ, Sur M.

Mol Psychiatry. 2018 Apr;23(4):791. doi: 10.1038/mp.2018.5. No abstract available.

PMID:
29565043
8.

Cytotoxic Escherichia coli strains encoding colibactin isolated from immunocompromised mice with urosepsis and meningitis.

Bakthavatchalu V, Wert KJ, Feng Y, Mannion A, Ge Z, Garcia A, Scott KE, Caron TJ, Madden CM, Jacobsen JT, Victora G, Jaenisch R, Fox JG.

PLoS One. 2018 Mar 19;13(3):e0194443. doi: 10.1371/journal.pone.0194443. eCollection 2018.

9.

Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene.

Liu XS, Wu H, Krzisch M, Wu X, Graef J, Muffat J, Hnisz D, Li CH, Yuan B, Xu C, Li Y, Vershkov D, Cacace A, Young RA, Jaenisch R.

Cell. 2018 Feb 22;172(5):979-992.e6. doi: 10.1016/j.cell.2018.01.012. Epub 2018 Feb 15.

PMID:
29456084
10.

Mechanisms of gene regulation in human embryos and pluripotent stem cells.

Theunissen TW, Jaenisch R.

Development. 2017 Dec 15;144(24):4496-4509. doi: 10.1242/dev.157404. Review.

11.

YY1 Is a Structural Regulator of Enhancer-Promoter Loops.

Weintraub AS, Li CH, Zamudio AV, Sigova AA, Hannett NM, Day DS, Abraham BJ, Cohen MA, Nabet B, Buckley DL, Guo YE, Hnisz D, Jaenisch R, Bradner JE, Gray NS, Young RA.

Cell. 2017 Dec 14;171(7):1573-1588.e28. doi: 10.1016/j.cell.2017.11.008. Epub 2017 Dec 7.

12.

S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models.

Oh CK, Sultan A, Platzer J, Dolatabadi N, Soldner F, McClatchy DB, Diedrich JK, Yates JR 3rd, Ambasudhan R, Nakamura T, Jaenisch R, Lipton SA.

Cell Rep. 2017 Nov 21;21(8):2171-2182. doi: 10.1016/j.celrep.2017.10.068.

13.

Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells.

Semrau S, Goldmann JE, Soumillon M, Mikkelsen TS, Jaenisch R, van Oudenaarden A.

Nat Commun. 2017 Oct 23;8(1):1096. doi: 10.1038/s41467-017-01076-4.

14.

Human Embryo Editing: Opportunities and Importance of Transnational Cooperation.

Pei D, Beier DW, Levy-Lahad E, Marchant G, Rossant J, Izpisua Belmonte JC, Lovell-Badge R, Jaenisch R, Charo A, Baltimore D.

Cell Stem Cell. 2017 Oct 5;21(4):423-426. doi: 10.1016/j.stem.2017.09.010.

PMID:
28985523
15.

An Endogenously Tagged Fluorescent Fusion Protein Library in Mouse Embryonic Stem Cells.

Harikumar A, Edupuganti RR, Sorek M, Azad GK, Markoulaki S, Sehnalová P, Legartová S, Bártová E, Farkash-Amar S, Jaenisch R, Alon U, Meshorer E.

Stem Cell Reports. 2017 Oct 10;9(4):1304-1314. doi: 10.1016/j.stemcr.2017.08.022. Epub 2017 Sep 28.

16.

Alternative SET/TAFI Promoters Regulate Embryonic Stem Cell Differentiation.

Edupuganti RR, Harikumar A, Aaronson Y, Biran A, Sailaja BS, Nissim-Rafinia M, Azad GK, Cohen MA, Park JE, Shivalila CS, Markoulaki S, Sze SK, Jaenisch R, Meshorer E.

Stem Cell Reports. 2017 Oct 10;9(4):1291-1303. doi: 10.1016/j.stemcr.2017.08.021. Epub 2017 Sep 28.

17.

MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling.

Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, Haggarty SJ, Sur M.

Mol Psychiatry. 2018 Apr;23(4):1051-1065. doi: 10.1038/mp.2017.86. Epub 2017 Apr 25.

18.

SMARCE1 is required for the invasive progression of in situ cancers.

Sokol ES, Feng YX, Jin DX, Tizabi MD, Miller DH, Cohen MA, Sanduja S, Reinhardt F, Pandey J, Superville DA, Jaenisch R, Gupta PB.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4153-4158. doi: 10.1073/pnas.1703931114. Epub 2017 Apr 4.

19.

Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors.

Feng J, Pena CJ, Purushothaman I, Engmann O, Walker D, Brown AN, Issler O, Doyle M, Harrigan E, Mouzon E, Vialou V, Shen L, Dawlaty MM, Jaenisch R, Nestler EJ.

Neuropsychopharmacology. 2017 Jul;42(8):1657-1669. doi: 10.1038/npp.2017.6. Epub 2017 Jan 11.

20.

Induction of Expansion and Folding in Human Cerebral Organoids.

Li Y, Muffat J, Omer A, Bosch I, Lancaster MA, Sur M, Gehrke L, Knoblich JA, Jaenisch R.

Cell Stem Cell. 2017 Mar 2;20(3):385-396.e3. doi: 10.1016/j.stem.2016.11.017. Epub 2016 Dec 29.

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