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Items: 1 to 20 of 94

1.

Synthesis, stability and mechanistic studies of potent anticryptococcal hexapeptides.

Shenmar K, Sharma KK, Wangoo N, Maurya IK, Kumar V, Khan SI, Jacob MR, Tikoo K, Jain R.

Eur J Med Chem. 2017 May 26;132:192-203. doi: 10.1016/j.ejmech.2017.03.046. Epub 2017 Mar 24.

PMID:
28363154
2.

Biological evaluation of phytoconstituents from Polygonum hydropiper.

Xiao H, Rao Ravu R, Tekwani BL, Li W, Liu WB, Jacob MR, Khan SI, Cai X, Peng CY, Khan IA, Li XC, Wang W.

Nat Prod Res. 2016 Dec 21:1-5. doi: 10.1080/14786419.2016.1269094. [Epub ahead of print]

PMID:
28000515
3.

Bioactive Formylated Flavonoids from Eugenia rigida: Isolation, Synthesis, and X-ray Crystallography.

Zaki MA, Nanayakkara NP, Hetta MH, Jacob MR, Khan SI, Mohammed R, Ibrahim MA, Samoylenko V, Coleman C, Fronczek FR, Ferreira D, Muhammad I.

J Nat Prod. 2016 Sep 23;79(9):2341-9. doi: 10.1021/acs.jnatprod.6b00474. Epub 2016 Sep 12.

PMID:
27618204
4.

Synthesis of Natural Acylphloroglucinol-Based Antifungal Compounds against Cryptococcus Species.

Yu Q, Ravu RR, Jacob MR, Khan SI, Agarwal AK, Yu BY, Li XC.

J Nat Prod. 2016 Sep 23;79(9):2195-201. doi: 10.1021/acs.jnatprod.6b00224. Epub 2016 Sep 1.

PMID:
27584935
5.

Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum.

Shi YN, Liu FF, Jacob MR, Li XC, Zhu HT, Wang D, Cheng RR, Yang CR, Xu M, Zhang YJ.

Planta Med. 2017 Jan;83(1-02):143-150. doi: 10.1055/s-0042-109778. Epub 2016 Jul 12.

PMID:
27405106
6.

New ent-Clerodane and Abietane Diterpenoids from the Roots of Kenyan Croton megalocarpoides Friis & M. G. Gilbert.

Ndunda B, Langat MK, Mulholland DA, Eastman H, Jacob MR, Khan SI, Walker LA, Muhammad I, Kerubo LO, Midiwo JO.

Planta Med. 2016 Jul;82(11-12):1079-86. doi: 10.1055/s-0042-108857. Epub 2016 Jun 10.

PMID:
27286332
7.

Diversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparum.

Zhang J, Bowling JJ, Smithson D, Clark J, Jacob MR, Khan SI, Tekwani BL, Connelly M, Samoylenko V, Ibrahim MA, Zaki MA, Wang M, Hester JP, Tu Y, Jeffries C, Twarog N, Shelat AA, Walker LA, Muhammad I, Guy RK.

Malar J. 2016 May 10;15(1):270. doi: 10.1186/s12936-016-1313-7.

8.

Antibacterial Prenylated Acylphloroglucinols from Psorothamnus fremontii.

Yu Q, Ravu RR, Xu QM, Ganji S, Jacob MR, Khan SI, Yu BY, Li XC.

J Nat Prod. 2015 Nov 25;78(11):2748-53. doi: 10.1021/acs.jnatprod.5b00721. Epub 2015 Oct 15.

PMID:
26469557
9.

LC-MS- and (1)H NMR Spectroscopy-Guided Identification of Antifungal Diterpenoids from Sagittaria latifolia.

Ravu RR, Jacob MR, Jeffries C, Tu Y, Khan SI, Agarwal AK, Guy RK, Walker LA, Clark AM, Li XC.

J Nat Prod. 2015 Sep 25;78(9):2255-9. doi: 10.1021/acs.jnatprod.5b00470. Epub 2015 Sep 15.

PMID:
26371504
10.

Antimicrobial and Antileishmanial Activities of Diterpenoids Isolated from the Roots of Salvia deserta.

Búfalo J, Cantrell CL, Jacob MR, Schrader KK, Tekwani BL, Kustova TS, Ali A, Boaro CS.

Planta Med. 2016 Jan;82(1-2):131-7. doi: 10.1055/s-0035-1557875. Epub 2015 Aug 26.

PMID:
26308356
11.

Fungi associated with rocks of the Atacama Desert: taxonomy, distribution, diversity, ecology and bioprospection for bioactive compounds.

Gonçalves VN, Cantrell CL, Wedge DE, Ferreira MC, Soares MA, Jacob MR, Oliveira FS, Galante D, Rodrigues F, Alves TM, Zani CL, Junior PA, Murta S, Romanha AJ, Barbosa EC, Kroon EG, Oliveira JG, Gomez-Silva B, Galetovic A, Rosa CA, Rosa LH.

Environ Microbiol. 2016 Jan;18(1):232-45. doi: 10.1111/1462-2920.13005. Epub 2015 Sep 28.

PMID:
26235221
12.

Anti-vancomycin-resistant Enterococcus faecium and E. faecalis activities of (-)-gossypol and derivatives from Thespesia garckeana.

Masila VM, Midiwo JO, Zhang J, Gisacho BM, Munayi R, Omosa LK, Wiggers FT, Jacob MR, Walker LA, Muhammad I.

Nat Prod Commun. 2015 Apr;10(4):613-6.

PMID:
25973489
13.

Bacillusin A, an Antibacterial Macrodiolide from Bacillus amyloliquefaciens AP183.

Ravu RR, Jacob MR, Chen X, Wang M, Nasrin S, Kloepper JW, Liles MR, Mead DA, Khan IA, Li XC.

J Nat Prod. 2015 Apr 24;78(4):924-8. doi: 10.1021/np500911k. Epub 2015 Mar 10.

PMID:
25756620
14.

Evaluation of three medicinal plant extracts against Plasmodium falciparum and selected microganisms.

Falodun A, Imieje V, Erharuyi O, Ahomafor J, Jacob MR, Khan SI, Hamann MT.

Afr J Tradit Complement Altern Med. 2014 Jun 4;11(4):142-6. eCollection 2014.

15.

Development of an antifungal denture adhesive film for oral candidiasis utilizing hot melt extrusion technology.

Park JB, Prodduturi S, Morott J, Kulkarni VI, Jacob MR, Khan SI, Stodghill SP, Repka MA.

Expert Opin Drug Deliv. 2015 Jan;12(1):1-13. doi: 10.1517/17425247.2014.949235. Epub 2014 Aug 29.

PMID:
25169007
16.

Synthesis and Antimicrobial Activities of His(2-aryl)-Arg and Trp-His(2-aryl) Classes of Dipeptidomimetics.

Mahindra A, Sharma KK, Rathore D, Khan SI, Jacob MR, Jain R.

Medchemcomm. 2014 May 1;5(5):671-676.

17.

Discovery of Short Peptides Exhibiting High Potency against Cryptococcus neoformans.

Mahindra A, Bagra N, Wangoo N, Khan SI, Jacob MR, Jain R.

ACS Med Chem Lett. 2014 Jan 15;5(4):315-20. doi: 10.1021/ml500011v. eCollection 2014 Apr 10.

18.

Synthetically modified L-histidine-rich peptidomimetics exhibit potent activity against Cryptococcus neoformans.

Mahindra A, Bagra N, Wangoo N, Jain R, Khan SI, Jacob MR, Jain R.

Bioorg Med Chem Lett. 2014 Jul 15;24(14):3150-4. doi: 10.1016/j.bmcl.2014.04.120. Epub 2014 May 10.

19.
20.

UPLC-MS-ELSD-PDA as a powerful dereplication tool to facilitate compound identification from small-molecule natural product libraries.

Yang J, Liang Q, Wang M, Jeffries C, Smithson D, Tu Y, Boulos N, Jacob MR, Shelat AA, Wu Y, Ravu RR, Gilbertson R, Avery MA, Khan IA, Walker LA, Guy RK, Li XC.

J Nat Prod. 2014 Apr 25;77(4):902-9. doi: 10.1021/np4009706. Epub 2014 Mar 11.

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