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Clinical and genetic analysis in a large Chinese cohort of patients with X-linked hypophosphatemia.

Zhang C, Zhao Z, Sun Y, Xu L, JiaJue R, Cui L, Pang Q, Jiang Y, Li M, Wang O, He X, He S, Nie M, Xing X, Meng X, Zhou X, Yan L, Kaplan JM, Insogna KL, Xia W.

Bone. 2019 Jan 23;121:212-220. doi: 10.1016/j.bone.2019.01.021. [Epub ahead of print]


Primary Hyperparathyroidism.

Insogna KL.

N Engl J Med. 2018 Dec 20;379(25):e43. doi: 10.1056/NEJMc1813648. No abstract available.


Primary Hyperparathyroidism.

Insogna KL.

N Engl J Med. 2018 Sep 13;379(11):1050-1059. doi: 10.1056/NEJMcp1714213. Review. No abstract available.


The contribution of cross-talk between the cell-surface proteins CD36 and CD47-TSP-1 in osteoclast formation and function.

Koduru SV, Sun BH, Walker JM, Zhu M, Simpson C, Dhodapkar M, Insogna KL.

J Biol Chem. 2018 Sep 28;293(39):15055-15069. doi: 10.1074/jbc.RA117.000633. Epub 2018 Aug 6.


A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial Evaluating the Efficacy of Burosumab, an Anti-FGF23 Antibody, in Adults With X-Linked Hypophosphatemia: Week 24 Primary Analysis.

Insogna KL, Briot K, Imel EA, Kamenick√Ĺ P, Ruppe MD, Portale AA, Weber T, Pitukcheewanont P, Cheong HI, Jan de Beur S, Imanishi Y, Ito N, Lachmann RH, Tanaka H, Perwad F, Zhang L, Chen CY, Theodore-Oklota C, Mealiffe M, San Martin J, Carpenter TO; AXLES 1 Investigators.

J Bone Miner Res. 2018 Aug;33(8):1383-1393. doi: 10.1002/jbmr.3475. Epub 2018 Jun 26.


Animal versus plant protein and adult bone health: A systematic review and meta-analysis from the National Osteoporosis Foundation.

Shams-White MM, Chung M, Fu Z, Insogna KL, Karlsen MC, LeBoff MS, Shapses SA, Sackey J, Shi J, Wallace TC, Weaver CM.

PLoS One. 2018 Feb 23;13(2):e0192459. doi: 10.1371/journal.pone.0192459. eCollection 2018. Review.


Three-Month Randomized Clinical Trial of Nasal Calcitonin in Adults with X-linked Hypophosphatemia.

Sullivan R, Abraham A, Simpson C, Olear E, Carpenter T, Deng Y, Chen C, Insogna KL.

Calcif Tissue Int. 2018 Jun;102(6):666-670. doi: 10.1007/s00223-017-0382-0. Epub 2018 Jan 30.


Vertebral fractures among breast cancer survivors in China: a cross-sectional study of prevalence and health services gaps.

Hsieh E, Wang Q, Zhang R, Niu X, Xia W, Fraenkel L, Insogna KL, Li J, Smith JS, Zhou C, Qiao YL, Zhang P.

BMC Cancer. 2018 Jan 30;18(1):104. doi: 10.1186/s12885-018-4014-5.


Selective deletion of the soluble Colony-Stimulating Factor 1 isoform in vivo prevents estrogen-deficiency bone loss in mice.

Yao GQ, Troiano N, Simpson CA, Insogna KL.

Bone Res. 2017 Nov 14;5:17022. doi: 10.1038/boneres.2017.22. eCollection 2017.


Associations among circulating colony-stimulating factor-1, estrogen, and bone mineral density in postmenopausal women: results from a randomized placebo-controlled trial.

Haas AV, Cong E, Simpson CA, Sukumar N, Deng Y, Insogna KL.

Menopause. 2018 Feb;25(2):197-201. doi: 10.1097/GME.0000000000000974.


Diagnosis and Management of Osteopetrosis: Consensus Guidelines From the Osteopetrosis Working Group.

Wu CC, Econs MJ, DiMeglio LA, Insogna KL, Levine MA, Orchard PJ, Miller WP, Petryk A, Rush ET, Shoback DM, Ward LM, Polgreen LE.

J Clin Endocrinol Metab. 2017 Sep 1;102(9):3111-3123. doi: 10.1210/jc.2017-01127. Review.


The Effect of Dietary Glycemic Properties on Markers of Inflammation, Insulin Resistance, and Body Composition in Postmenopausal American Women: An Ancillary Study from a Multicenter Protein Supplementation Trial.

Stojkovic V, Simpson CA, Sullivan RR, Cusano AM, Kerstetter JE, Kenny AM, Insogna KL, Bihuniak JD.

Nutrients. 2017 May 11;9(5). pii: E484. doi: 10.3390/nu9050484.


Dietary protein and bone health: a systematic review and meta-analysis from the National Osteoporosis Foundation.

Shams-White MM, Chung M, Du M, Fu Z, Insogna KL, Karlsen MC, LeBoff MS, Shapses SA, Sackey J, Wallace TC, Weaver CM.

Am J Clin Nutr. 2017 Jun;105(6):1528-1543. doi: 10.3945/ajcn.116.145110. Epub 2017 Apr 12. Review.


Impact of gain-of-function mutations in the low-density lipoprotein receptor-related protein 5 (LRP5) on glucose and lipid homeostasis.

Foer D, Zhu M, Cardone RL, Simpson C, Sullivan R, Nemiroff S, Lee G, Kibbey RG, Petersen KF, Insogna KL.

Osteoporos Int. 2017 Jun;28(6):2011-2017. doi: 10.1007/s00198-017-3977-4. Epub 2017 Mar 10.


Pioglitazone and Risk for Bone Fracture: Safety Data From a Randomized Clinical Trial.

Viscoli CM, Inzucchi SE, Young LH, Insogna KL, Conwit R, Furie KL, Gorman M, Kelly MA, Lovejoy AM, Kernan WN; IRIS Trial Investigators.

J Clin Endocrinol Metab. 2017 Mar 1;102(3):914-922. doi: 10.1210/jc.2016-3237.


The liver throws the skeleton a bone (resorption factor).

Chung C, Insogna KL.

Hepatology. 2016 Sep;64(3):977-9. doi: 10.1002/hep.28688. Epub 2016 Jul 25. No abstract available.


Longitudinal increase in vitamin D binding protein levels after initiation of tenofovir/lamivudine/efavirenz among individuals with HIV.

Hsieh E, Fraenkel L, Han Y, Xia W, Insogna KL, Yin MT, Zhu T, Cheng X, Li T.

AIDS. 2016 Jul 31;30(12):1935-42. doi: 10.1097/QAD.0000000000001131.


Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo.

Zhu M, Sun BH, Saar K, Simpson C, Troiano N, Dallas SL, Tiede-Lewis LM, Nevius E, Pereira JP, Weinstein RS, Tommasini SM, Insogna KL.

J Bone Miner Res. 2016 Apr;31(4):864-73. doi: 10.1002/jbmr.2733. Epub 2015 Nov 18.


Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

Ho PC, Bihuniak JD, Macintyre AN, Staron M, Liu X, Amezquita R, Tsui YC, Cui G, Micevic G, Perales JC, Kleinstein SH, Abel ED, Insogna KL, Feske S, Locasale JW, Bosenberg MW, Rathmell JC, Kaech SM.

Cell. 2015 Sep 10;162(6):1217-28. doi: 10.1016/j.cell.2015.08.012. Epub 2015 Aug 27.


Dietary Protein and Vitamin D Intake and Risk of Falls: A Secondary Analysis of Postmenopausal Women from the Study of Osteoporotic Fractures.

Larocque SC, Kerstetter JE, Cauley JA, Insogna KL, Ensrud K, Lui LY, Allore HG.

J Nutr Gerontol Geriatr. 2015;34(3):305-18. doi: 10.1080/21551197.2015.1054574.

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