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Items: 1 to 20 of 106

1.

Evaluation of first generation synthetic cannabinoids on binding at non-cannabinoid receptors and in a battery of in vivo assays in mice.

Wiley JL, Lefever TW, Marusich JA, Grabenauer M, Moore KN, Huffman JW, Thomas BF.

Neuropharmacology. 2016 Nov;110(Pt A):143-153. doi: 10.1016/j.neuropharm.2016.07.016. Epub 2016 Jul 20.

PMID:
27449567
2.

The influence of beta-arrestin2 on cannabinoid CB1 receptor coupling to G-proteins and subcellular localization and relative levels of beta-arrestin1 and 2 in mouse brain.

Breivogel CS, Puri V, Lambert JM, Hill DK, Huffman JW, Razdan RK.

J Recept Signal Transduct Res. 2013 Dec;33(6):367-79. doi: 10.3109/10799893.2013.838787. Epub 2013 Oct 4.

PMID:
24094141
3.

Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids.

Wiley JL, Marusich JA, Huffman JW.

Life Sci. 2014 Feb 27;97(1):55-63. doi: 10.1016/j.lfs.2013.09.011. Epub 2013 Sep 23. Review.

4.

Use of SPME-HS-GC-MS for the analysis of herbal products containing synthetic cannabinoids.

Cox AO, Daw RC, Mason MD, Grabenauer M, Pande PG, Davis KH, Wiley JL, Stout PR, Thomas BF, Huffman JW.

J Anal Toxicol. 2012 Jun;36(5):293-302. doi: 10.1093/jat/bks025.

5.

Synthesis and pharmacology of 1-alkyl-3-(1-naphthoyl)indoles: steric and electronic effects of 4- and 8-halogenated naphthoyl substituents.

Wiley JL, Smith VJ, Chen J, Martin BR, Huffman JW.

Bioorg Med Chem. 2012 Mar 15;20(6):2067-81. doi: 10.1016/j.bmc.2012.01.038. Epub 2012 Jan 30.

6.

1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice.

Wiley JL, Marusich JA, Martin BR, Huffman JW.

Drug Alcohol Depend. 2012 Jun 1;123(1-3):148-53. doi: 10.1016/j.drugalcdep.2011.11.001. Epub 2011 Nov 27.

7.

Hijacking of Basic Research: The Case of Synthetic Cannabinoids.

Wiley JL, Marusich JA, Huffman JW, Balster RL, Thomas BF.

Methods Rep RTI Press. 2011 Nov;2011. pii: 17971.

8.

Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB(1) receptor antagonist.

Wiley JL, Breivogel CS, Mahadevan A, Pertwee RG, Cascio MG, Bolognini D, Huffman JW, Walentiny DM, Vann RE, Razdan RK, Martin BR.

Eur J Pharmacol. 2011 Jan 25;651(1-3):96-105. doi: 10.1016/j.ejphar.2010.10.085. Epub 2010 Nov 27.

9.

8-Chloro- and 5,8-Dichloro1-naphthoic Acids.

Chen J, Smith VJ, Huffman JW.

Org Prep Proced Int. 2010;42(5):490-493. No abstract available.

10.

1-Bromo-3-(1',1'-dimethylalkyl)-1-deoxy-Δ(8)-tetrahydrocannabinols: New selective ligands for the cannabinoid CB(2) receptor.

Huffman JW, Hepburn SA, Lyutenko N, Thompson AL, Wiley JL, Selley DE, Martin BR.

Bioorg Med Chem. 2010 Nov 15;18(22):7809-15. doi: 10.1016/j.bmc.2010.09.061. Epub 2010 Sep 29.

11.

Synthesis and pharmacology of 1-methoxy analogs of CP-47,497.

Huffman JW, Hepburn SA, Reggio PH, Hurst DP, Wiley JL, Martin BR.

Bioorg Med Chem. 2010 Aug 1;18(15):5475-82. doi: 10.1016/j.bmc.2010.06.054. Epub 2010 Jun 22.

12.

Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice.

Vann RE, Warner JA, Bushell K, Huffman JW, Martin BR, Wiley JL.

Eur J Pharmacol. 2009 Aug 1;615(1-3):102-7. doi: 10.1016/j.ejphar.2009.05.010. Epub 2009 May 23.

13.
14.

Sensitivity to delta9-tetrahydrocannabinol is selectively enhanced in beta-arrestin2 -/- mice.

Breivogel CS, Lambert JM, Gerfin S, Huffman JW, Razdan RK.

Behav Pharmacol. 2008 Jul;19(4):298-307. doi: 10.1097/FBP.0b013e328308f1e6.

15.

Recent advances in the development of selective ligands for the cannabinoid CB(2) receptor.

Marriott KS, Huffman JW.

Curr Top Med Chem. 2008;8(3):187-204. Review.

PMID:
18289088
16.

CB2 cannabinoid receptor agonists attenuate TNF-alpha-induced human vascular smooth muscle cell proliferation and migration.

Rajesh M, Mukhopadhyay P, Haskó G, Huffman JW, Mackie K, Pacher P.

Br J Pharmacol. 2008 Jan;153(2):347-57. Epub 2007 Nov 12.

17.

Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 selective ligands.

Poso A, Huffman JW.

Br J Pharmacol. 2008 Jan;153(2):335-46. Epub 2007 Nov 5. Review.

18.

Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940.

Huffman JW, Thompson AL, Wiley JL, Martin BR.

Bioorg Med Chem. 2008 Jan 1;16(1):322-35. Epub 2007 Sep 22.

19.

CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.

Rajesh M, Mukhopadhyay P, Bátkai S, Haskó G, Liaudet L, Huffman JW, Csiszar A, Ungvari Z, Mackie K, Chatterjee S, Pacher P.

Am J Physiol Heart Circ Physiol. 2007 Oct;293(4):H2210-8. Epub 2007 Jul 27.

20.

Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury.

Bátkai S, Osei-Hyiaman D, Pan H, El-Assal O, Rajesh M, Mukhopadhyay P, Hong F, Harvey-White J, Jafri A, Haskó G, Huffman JW, Gao B, Kunos G, Pacher P.

FASEB J. 2007 Jun;21(8):1788-800. Epub 2007 Feb 27.

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