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Items: 1 to 20 of 35

1.

Erratum: Effective combinatorial immunotherapy for castration-resistant prostate cancer.

Lu X, Horner JW, Paul E, Shang X, Troncoso P, Deng P, Jiang S, Chang Q, Spring DJ, Sharma P, Zebala JA, Maeda DY, Wang YA, DePinho RA.

Nature. 2017 May 3;545(7652):116. doi: 10.1038/nature22348. No abstract available.

PMID:
28470201
2.

Effective combinatorial immunotherapy for castration-resistant prostate cancer.

Lu X, Horner JW, Paul E, Shang X, Troncoso P, Deng P, Jiang S, Chang Q, Spring DJ, Sharma P, Zebala JA, Maeda DY, Wang YA, DePinho RA.

Nature. 2017 Mar 30;543(7647):728-732. doi: 10.1038/nature21676. Epub 2017 Mar 20. Erratum in: Nature. 2017 May 3;545(7652):116.

3.

Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation.

Shingu T, Ho AL, Yuan L, Zhou X, Dai C, Zheng S, Wang Q, Zhong Y, Chang Q, Horner JW, Liebelt BD, Yao Y, Hu B, Chen Y, Fuller GN, Verhaak RG, Heimberger AB, Hu J.

Nat Genet. 2017 Jan;49(1):75-86. doi: 10.1038/ng.3711. Epub 2016 Nov 14.

4.

Dual Roles of RNF2 in Melanoma Progression.

Rai K, Akdemir KC, Kwong LN, Fiziev P, Wu CJ, Keung EZ, Sharma S, Samant NS, Williams M, Axelrad JB, Shah A, Yang D, Grimm EA, Barton MC, Milton DR, Heffernan TP, Horner JW, Ekmekcioglu S, Lazar AJ, Ernst J, Chin L.

Cancer Discov. 2015 Dec;5(12):1314-27. doi: 10.1158/2159-8290.CD-15-0493. Epub 2015 Oct 8.

5.

Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndrome.

Colla S, Ong DS, Ogoti Y, Marchesini M, Mistry NA, Clise-Dwyer K, Ang SA, Storti P, Viale A, Giuliani N, Ruisaard K, Ganan Gomez I, Bristow CA, Estecio M, Weksberg DC, Ho YW, Hu B, Genovese G, Pettazzoni P, Multani AS, Jiang S, Hua S, Ryan MC, Carugo A, Nezi L, Wei Y, Yang H, D'Anca M, Zhang L, Gaddis S, Gong T, Horner JW, Heffernan TP, Jones P, Cooper LJ, Liang H, Kantarjian H, Wang YA, Chin L, Bueso-Ramos C, Garcia-Manero G, DePinho RA.

Cancer Cell. 2015 May 11;27(5):644-57. doi: 10.1016/j.ccell.2015.04.007.

6.

Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms.

Klingler S, Guo B, Yao J, Yan H, Zhang L, Vaseva AV, Chen S, Canoll P, Horner JW, Wang YA, Paik JH, Ying H, Zheng H.

Cancer Res. 2015 May 15;75(10):2109-19. doi: 10.1158/0008-5472.CAN-14-3122. Epub 2015 Mar 25.

7.

Deletion of PREPl causes growth impairment and hypotonia in mice.

Lone AM, Leidl M, McFedries AK, Horner JW, Creemers J, Saghatelian A.

PLoS One. 2014 Feb 28;9(2):e89160. doi: 10.1371/journal.pone.0089160. eCollection 2014.

8.

PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.

Israelsen WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G, Li J, Yu Y, Sasaki M, Horner JW, Burga LN, Xie J, Jurczak MJ, DePinho RA, Clish CB, Jacks T, Kibbey RG, Wulf GM, Di Vizio D, Mills GB, Cantley LC, Vander Heiden MG.

Cell. 2013 Oct 10;155(2):397-409. doi: 10.1016/j.cell.2013.09.025.

9.

Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases.

Ding Z, Wu CJ, Jaskelioff M, Ivanova E, Kost-Alimova M, Protopopov A, Chu GC, Wang G, Lu X, Labrot ES, Hu J, Wang W, Xiao Y, Zhang H, Zhang J, Zhang J, Gan B, Perry SR, Jiang S, Li L, Horner JW, Wang YA, Chin L, DePinho RA.

Cell. 2012 Mar 2;148(5):896-907. doi: 10.1016/j.cell.2012.01.039. Epub 2012 Feb 16.

10.

A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis.

Jia W, Wang S, Horner JW, Wang N, Wang H, Gunther EJ, DePinho RA, Zhu J.

FASEB J. 2011 Mar;25(3):979-89. doi: 10.1096/fj.10-173989. Epub 2010 Dec 6.

11.

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.

Jaskelioff M, Muller FL, Paik JH, Thomas E, Jiang S, Adams AC, Sahin E, Kost-Alimova M, Protopopov A, Cadiñanos J, Horner JW, Maratos-Flier E, Depinho RA.

Nature. 2011 Jan 6;469(7328):102-6. doi: 10.1038/nature09603. Epub 2010 Nov 28.

12.

Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas.

Zhou Y, Rideout WM 3rd, Zi T, Bressel A, Reddypalli S, Rancourt R, Woo JK, Horner JW, Chin L, Chiu MI, Bosenberg M, Jacks T, Clark SC, Depinho RA, Robinson MO, Heyer J.

Nat Biotechnol. 2010 Jan;28(1):71-8. doi: 10.1038/nbt.1595. Epub 2009 Dec 20.

PMID:
20023657
13.

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis.

Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, Miao L, Tothova Z, Horner JW, Carrasco DR, Jiang S, Gilliland DG, Chin L, Wong WH, Castrillon DH, DePinho RA.

Cell. 2007 Jan 26;128(2):309-23.

14.

Characterization of melanocyte-specific inducible Cre recombinase transgenic mice.

Bosenberg M, Muthusamy V, Curley DP, Wang Z, Hobbs C, Nelson B, Nogueira C, Horner JW 2nd, Depinho R, Chin L.

Genesis. 2006 May;44(5):262-7.

PMID:
16676322
15.

Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors.

Ji H, Zhao X, Yuza Y, Shimamura T, Li D, Protopopov A, Jung BL, McNamara K, Xia H, Glatt KA, Thomas RK, Sasaki H, Horner JW, Eck M, Mitchell A, Sun Y, Al-Hashem R, Bronson RT, Rabindran SK, Discafani CM, Maher E, Shapiro GI, Meyerson M, Wong KK.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7817-22. Epub 2006 May 3.

16.

Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production.

Safran M, Kim WY, O'Connell F, Flippin L, Günzler V, Horner JW, Depinho RA, Kaelin WG Jr.

Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):105-10. Epub 2005 Dec 22.

17.

Class IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy.

Luo J, McMullen JR, Sobkiw CL, Zhang L, Dorfman AL, Sherwood MC, Logsdon MN, Horner JW, DePinho RA, Izumo S, Cantley LC.

Mol Cell Biol. 2005 Nov;25(21):9491-502.

18.

p63 regulates commitment to the prostate cell lineage.

Signoretti S, Pires MM, Lindauer M, Horner JW, Grisanzio C, Dhar S, Majumder P, McKeon F, Kantoff PW, Sellers WR, Loda M.

Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11355-60. Epub 2005 Jul 28.

19.

Coxsackievirus and adenovirus receptor is essential for cardiomyocyte development.

Asher DR, Cerny AM, Weiler SR, Horner JW, Keeler ML, Neptune MA, Jones SN, Bronson RT, Depinho RA, Finberg RW.

Genesis. 2005 Jun;42(2):77-85.

PMID:
15864812
20.

Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination.

Safran M, Kim WY, Kung AL, Horner JW, DePinho RA, Kaelin WG Jr.

Mol Imaging. 2003 Oct;2(4):297-302.

PMID:
14717328

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