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Items: 1 to 20 of 304

1.

Synthesis, characterization, DNA binding, topoisomerase inhibition, and apoptosis induction studies of a novel cobalt(III) complex with a thiosemicarbazone ligand.

Beebe SJ, Celestine MJ, Bullock JL, Sandhaus S, Arca JF, Cropek DM, Ludvig TA, Foster SR, Clark JS, Beckford FA, Tano CM, Tonsel-White EA, Gurung RK, Stankavich CE, Tse-Dinh YC, Jarrett WL, Holder AA.

J Inorg Biochem. 2019 Nov 2;203:110907. doi: 10.1016/j.jinorgbio.2019.110907. [Epub ahead of print]

PMID:
31715377
2.

Plasmodium kinesin-8X associates with mitotic spindles and is essential for oocyst development during parasite proliferation and transmission.

Zeeshan M, Shilliday F, Liu T, Abel S, Mourier T, Ferguson DJP, Rea E, Stanway RR, Roques M, Williams D, Daniel E, Brady D, Roberts AJ, Holder AA, Pain A, Le Roch KG, Moores CA, Tewari R.

PLoS Pathog. 2019 Oct 10;15(10):e1008048. doi: 10.1371/journal.ppat.1008048. eCollection 2019 Oct.

3.

Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission.

Zeeshan M, Ferguson DJ, Abel S, Burrrell A, Rea E, Brady D, Daniel E, Delves M, Vaughan S, Holder AA, Le Roch KG, Moores CA, Tewari R.

Life Sci Alliance. 2019 Aug 13;2(4). pii: e201900488. doi: 10.26508/lsa.201900488. Print 2019 Aug.

4.

Systematic analysis of Plasmodium myosins reveals differential expression, localisation, and function in invasive and proliferative parasite stages.

Wall RJ, Zeeshan M, Katris NJ, Limenitakis R, Rea E, Stock J, Brady D, Waller RF, Holder AA, Tewari R.

Cell Microbiol. 2019 Oct;21(10):e13082. doi: 10.1111/cmi.13082. Epub 2019 Jul 23.

PMID:
31283102
5.

Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites.

Knuepfer E, Wright KE, Kumar Prajapati S, Rawlinson TA, Mohring F, Koch M, Lyth OR, Howell SA, Villasis E, Snijders AP, Moon RW, Draper SJ, Rosanas-Urgell A, Higgins MK, Baum J, Holder AA.

PLoS Pathog. 2019 Jun 11;15(6):e1007809. doi: 10.1371/journal.ppat.1007809. eCollection 2019 Jun.

6.

Structure-Guided Identification of Resistance Breaking Antimalarial N‑Myristoyltransferase Inhibitors.

Schlott AC, Mayclin S, Reers AR, Coburn-Flynn O, Bell AS, Green J, Knuepfer E, Charter D, Bonnert R, Campo B, Burrows J, Lyons-Abbott S, Staker BL, Chung CW, Myler PJ, Fidock DA, Tate EW, Holder AA.

Cell Chem Biol. 2019 Jul 18;26(7):991-1000.e7. doi: 10.1016/j.chembiol.2019.03.015. Epub 2019 May 9.

7.

Plasmodium centrin PbCEN-4 localizes to the putative MTOC and is dispensable for malaria parasite proliferation.

Roques M, Stanway RR, Rea EI, Markus R, Brady D, Holder AA, Guttery DS, Tewari R.

Biol Open. 2019 Jan 29;8(1). pii: bio036822. doi: 10.1242/bio.036822.

8.

Novel Survivin Inhibitor for Suppressing Pancreatic Cancer Cells Growth via Downregulating Sp1 and Sp3 Transcription Factors.

Hurtado M, Sankpal UT, Kaba A, Mahammad S, Chhabra J, Brown DT, Gurung RK, Holder AA, Vishwanatha JK, Basha R.

Cell Physiol Biochem. 2018;51(4):1894-1907. doi: 10.1159/000495715. Epub 2018 Nov 30.

9.

Low plasma haptoglobin is a risk factor for life-threatening childhood severe malarial anemia and not an exclusive consequence of hemolysis.

Abah SE, Burté F, Marquet S, Brown BJ, Akinkunmi F, Oyinloye G, Afolabi NK, Omokhodion S, Lagunju I, Shokunbi WA, Wahlgren M, Dessein H, Argiro L, Dessein AJ, Noyvert B, Hunt L, Elgar G, Sodeinde O, Holder AA, Fernandez-Reyes D.

Sci Rep. 2018 Dec 3;8(1):17527. doi: 10.1038/s41598-018-35944-w.

10.

Towards lead compounds as anti-cancer agents via new phaeosphaeride A derivatives.

Abzianidze VV, Zakharenkova SA, Moiseeva NI, Beltyukov PP, Polukeev VA, Dubrovskii YA, Kuznetsov VA, Trishin YG, Mejia JE, Holder AA.

Bioorg Med Chem Lett. 2019 Jan 1;29(1):59-61. doi: 10.1016/j.bmcl.2018.11.003. Epub 2018 Nov 9.

PMID:
30447888
11.

Author Correction: Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis.

Wall RJ, Ferguson DJP, Freville A, Franke-Fayard B, Brady D, Zeeshan M, Bottrill AR, Wheatley S, Fry AM, Janse CJ, Yamano H, Holder AA, Guttery DS, Tewari R.

Sci Rep. 2018 Aug 21;8(1):12814. doi: 10.1038/s41598-018-30924-6.

12.

Ferrocene-based anilides: synthesis, structural characterization and inhibition of butyrylcholinesterase.

Altaf AA, Hamayun M, Lal B, Tahir MN, Holder AA, Badshah A, Crans DC.

Dalton Trans. 2018 Aug 29;47(34):11769-11781. doi: 10.1039/c8dt01726c.

PMID:
30117513
13.

Polynuclear ruthenium organometallic complexes containing a 1,3,5-triazine ligand: synthesis, DNA interaction, and biological activity.

Beckford FA, Niece MB, Lassiter BP, Beebe SJ, Holder AA.

J Biol Inorg Chem. 2018 Dec;23(8):1205-1217. doi: 10.1007/s00775-018-1599-8. Epub 2018 Jul 23.

PMID:
30039184
14.

Copper-tolfenamic acid: evaluation of stability and anti-cancer activity.

Hurtado M, Sankpal UT, Chhabra J, Brown DT, Maram R, Patel R, Gurung RK, Simecka J, Holder AA, Basha R.

Invest New Drugs. 2019 Feb;37(1):27-34. doi: 10.1007/s10637-018-0594-9. Epub 2018 May 15.

PMID:
29761244
15.

Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis.

Wall RJ, Ferguson DJP, Freville A, Franke-Fayard B, Brady D, Zeeshan M, Bottrill AR, Wheatley S, Fry AM, Janse CJ, Yamano H, Holder AA, Guttery DS, Tewari R.

Sci Rep. 2018 Apr 4;8(1):5610. doi: 10.1038/s41598-018-23871-9. Erratum in: Sci Rep. 2018 Aug 21;8(1):12814.

16.

N-Myristoylation as a Drug Target in Malaria: Exploring the Role of N-Myristoyltransferase Substrates in the Inhibitor Mode of Action.

Schlott AC, Holder AA, Tate EW.

ACS Infect Dis. 2018 Apr 13;4(4):449-457. doi: 10.1021/acsinfecdis.7b00203. Epub 2018 Feb 2. Review.

17.

A reference genome and methylome for the Plasmodium knowlesi A1-H.1 line.

Benavente ED, de Sessions PF, Moon RW, Grainger M, Holder AA, Blackman MJ, Roper C, Drakeley CJ, Pain A, Sutherland CJ, Hibberd ML, Campino S, Clark TG.

Int J Parasitol. 2018 Mar;48(3-4):191-196. doi: 10.1016/j.ijpara.2017.09.008. Epub 2017 Dec 16.

18.

Plasmodium Peekaboo: PK4 Mediates Parasite Latency.

Rea E, Holder AA, Tewari R.

Cell Host Microbe. 2017 Dec 13;22(6):724-725. doi: 10.1016/j.chom.2017.11.011.

19.

Photosensitized INA-Labelled protein 1 (PhIL1) is novel component of the inner membrane complex and is required for Plasmodium parasite development.

Saini E, Zeeshan M, Brady D, Pandey R, Kaiser G, Koreny L, Kumar P, Thakur V, Tatiya S, Katris NJ, Limenitakis RS, Kaur I, Green JL, Bottrill AR, Guttery DS, Waller RF, Heussler V, Holder AA, Mohmmed A, Malhotra P, Tewari R.

Sci Rep. 2017 Nov 14;7(1):15577. doi: 10.1038/s41598-017-15781-z.

20.

Coordination of different ligands to copper(II) and cobalt(III) metal centers enhances Zika virus and dengue virus loads in both arthropod cells and human keratinocytes.

Dutta S, Celestine MJ, Khanal S, Huddleston A, Simms C, Arca JF, Mitra A, Heller L, Kraj PJ, Ledizet M, Anderson JF, Neelakanta G, Holder AA, Sultana H.

Biochim Biophys Acta Gen Subj. 2018 Jan;1862(1):40-50. doi: 10.1016/j.bbagen.2017.10.004. Epub 2017 Oct 13.

PMID:
29030319

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