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Regulation of the polycomb protein Ring1B by self-ubiquitination or by E6-AP may have implications to the pathogenesis of Angelman syndrome.

Zaaroor-Regev D, de Bie P, Scheffner M, Noy T, Shemer R, Heled M, Stein I, Pikarsky E, Ciechanover A.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6788-93. doi: 10.1073/pnas.1003108107. Epub 2010 Mar 29.


Protein-binding elements establish in the oocyte the primary imprint of the Prader-Willi/Angelman syndromes domain.

Kaufman Y, Heled M, Perk J, Razin A, Shemer R.

Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10242-7. doi: 10.1073/pnas.0902087106. Epub 2009 Jun 8.


Polymorphisms in transporter and phase II metabolism genes as potential modifiers of the predisposition to and treatment outcome of de novo acute myeloid leukemia in Israeli ethnic groups.

Müller P, Asher N, Heled M, Cohen SB, Risch A, Rund D.

Leuk Res. 2008 Jun;32(6):919-29. doi: 10.1016/j.leukres.2007.10.011. Epub 2008 Jan 18.


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