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CPAP Therapy Delays Cardiovagal Reactivation and Decreases Arterial Renin-Angiotensin System Activity in Humans With Obstructive Sleep Apnea.

Nicholl DDM, Hanly PJ, Zalucky AA, Mann MC, MacRae JM, Poulin MJ, Handley GB, Sola DY, Ahmed SB.

J Clin Sleep Med. 2018 Aug 30. pii: jc-17-00627. [Epub ahead of print]


Profile of CPAP treated patients in Ontario, Canada, 2006-2013: a population-based cohort study.

Povitz M, Kendzerska T, Hanly PJ, Bray Jenkyn K, Allen B, George CFP, Shariff SZ.

Sleep Med. 2018 Jun 27;51:22-28. doi: 10.1016/j.sleep.2018.06.005. [Epub ahead of print]


Plasma Exosomes and Improvements in Endothelial Function by Angiotensin 2 Type 1 Receptor or Cyclooxygenase 2 Blockade following Intermittent Hypoxia.

Khalyfa A, Youssefnia N, Foster GE, Beaudin AE, Qiao Z, Pialoux V, Pun M, Hanly PJ, Kheirandish-Gozal L, Poulin MJ, Gozal D.

Front Neurol. 2017 Dec 22;8:709. doi: 10.3389/fneur.2017.00709. eCollection 2017.


Effect of Obstructive Sleep Apnea Treatment on Renal Function in Patients with Cardiovascular Disease.

Loffler KA, Heeley E, Freed R, Anderson CS, Brockway B, Corbett A, Chang CL, Douglas JA, Ferrier K, Graham N, Hamilton GS, Hlavac M, McArdle N, McLachlan J, Mukherjee S, Naughton MT, Thien F, Young A, Grunstein RR, Palmer LJ, Woodman RJ, Hanly PJ, McEvoy RD; SAVE (Sleep Apnea Cardiovascular Endpoints) Investigators.

Am J Respir Crit Care Med. 2017 Dec 1;196(11):1456-1462. doi: 10.1164/rccm.201703-0603OC.


Speciation and the Latitudinal Diversity Gradient: Insights from the Global Distribution of Endemic Fish.

Hanly PJ, Mittelbach GG, Schemske DW.

Am Nat. 2017 Jun;189(6):604-615. doi: 10.1086/691535. Epub 2017 Apr 7.


Impact of obstructive sleep apnoea and intermittent hypoxia on cardiovascular and cerebrovascular regulation.

Beaudin AE, Waltz X, Hanly PJ, Poulin MJ.

Exp Physiol. 2017 Jul 1;102(7):743-763. doi: 10.1113/EP086051. Epub 2017 Jun 27. Review.


Chronic Kidney Disease and Sleep Apnea Association of Kidney Disease With Obstructive Sleep Apnea in a Population Study of Men.

Adams RJ, Appleton SL, Vakulin A, Hanly PJ, McDonald SP, Martin SA, Lang CJ, Taylor AW, McEvoy RD, Antic NA, Catcheside PG, Vincent AD, Wittert GA.

Sleep. 2017 Jan 1;40(1). doi: 10.1093/sleep/zsw015.


Evaluation of an alternative care provider clinic for severe sleep-disordered breathing: a study protocol for a randomised controlled trial.

Ip-Buting A, Kelly J, Santana MJ, Penz ED, Flemons WW, Tsai WH, Fraser KL, Hanly PJ, Pendharkar SR.

BMJ Open. 2017 Mar 29;7(3):e014012. doi: 10.1136/bmjopen-2016-014012.


Evidence of association between sleep quality and APOE ε4 in healthy older adults: A pilot study.

Drogos LL, Gill SJ, Tyndall AV, Raneri JK, Parboosingh JS, Naef A, Guild KD, Eskes G, Hanly PJ, Poulin MJ.

Neurology. 2016 Oct 25;87(17):1836-1842.


Minimizing Interrater Variability in Staging Sleep by Use of Computer-Derived Features.

Younes M, Hanly PJ.

J Clin Sleep Med. 2016 Oct 15;12(10):1347-1356.


Effects of continuous positive airway pressure and isocapnic-hypoxia on cerebral autoregulation in patients with obstructive sleep apnoea.

Waltz X, Beaudin AE, Hanly PJ, Mitsis GD, Poulin MJ.

J Physiol. 2016 Dec 1;594(23):7089-7104. doi: 10.1113/JP272967.


Effect on Intermittent Hypoxia on Plasma Exosomal Micro RNA Signature and Endothelial Function in Healthy Adults.

Khalyfa A, Zhang C, Khalyfa AA, Foster GE, Beaudin AE, Andrade J, Hanly PJ, Poulin MJ, Gozal D.

Sleep. 2016 Dec 1;39(12):2077-2090. doi: 10.5665/sleep.6302.


Healthcare Use in Individuals with Obesity and Chronic Hypoxemia Treated for Sleep Disordered Breathing.

Povitz M, Tsai WH, Pendharkar SR, Hanly PJ, James MT.

J Clin Sleep Med. 2016 Apr 15;12(4):543-8. doi: 10.5664/jcsm.5686.


Immediate postarousal sleep dynamics: an important determinant of sleep stability in obstructive sleep apnea.

Younes M, Hanly PJ.

J Appl Physiol (1985). 2016 Apr 1;120(7):801-8. doi: 10.1152/japplphysiol.00880.2015. Epub 2015 Dec 30.


An observational study of the effectiveness of alternative care providers in the management of obstructive sleep apnea.

Pendharkar SR, Dechant A, Bischak DP, Tsai WH, Stevenson AM, Hanly PJ.

J Sleep Res. 2016 Apr;25(2):234-40. doi: 10.1111/jsr.12358. Epub 2015 Oct 27.


Treatment of Sleep Disordered Breathing Liberates Obese Hypoxemic Patients from Oxygen.

Povitz M, Hanly PJ, Pendharkar SR, James MT, Tsai WH.

PLoS One. 2015 Oct 9;10(10):e0140135. doi: 10.1371/journal.pone.0140135. eCollection 2015.


Nocturnal Hypoxemia Is Associated with White Matter Hyperintensities in Patients with a Minor Stroke or Transient Ischemic Attack.

Patel SK, Hanly PJ, Smith EE, Chan W, Coutts SB.

J Clin Sleep Med. 2015 Dec 15;11(12):1417-24. doi: 10.5664/jcsm.5278.


Nocturnal hypoxemia severity and renin-angiotensin system activity in obstructive sleep apnea.

Zalucky AA, Nicholl DD, Hanly PJ, Poulin MJ, Turin TC, Walji S, Handley GB, Raneri JK, Sola DY, Ahmed SB.

Am J Respir Crit Care Med. 2015 Oct 1;192(7):873-80. doi: 10.1164/rccm.201502-0383OC.


Consider the Kidney when Managing Obstructive Sleep Apnea.

Hanly PJ.

J Clin Sleep Med. 2015 Aug 15;11(8):845-6. doi: 10.5664/jcsm.4928. No abstract available.

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