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Items: 1 to 20 of 102


Deletion of GARP on mouse regulatory T cells is not sufficient to inhibit the growth of transplanted tumors.

Vermeersch E, Liénart S, Collignon A, Lucas S, Gallimore A, Gysemans C, Unutmaz D, Vanhoorelbeke K, De Meyer SF, Maes W, Deckmyn H.

Cell Immunol. 2018 Oct;332:129-133. doi: 10.1016/j.cellimm.2018.07.011. Epub 2018 Jul 30.


Magnetoliposomes as Contrast Agents for Longitudinal in vivo Assessment of Transplanted Pancreatic Islets in a Diabetic Rat Model.

Garcia Ribeiro RS, Gysemans C, da Cunha JPMCM, Manshian BB, Jirak D, Kriz J, Gallo J, Bañobre-López M, Struys T, De Cuyper M, Mathieu C, Soenen SJ, Gsell W, Himmelreich U.

Sci Rep. 2018 Jul 31;8(1):11487. doi: 10.1038/s41598-018-29136-9.


Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation.

Staels W, Verdonck Y, Heremans Y, Leuckx G, De Groef S, Heirman C, de Koning E, Gysemans C, Thielemans K, Baeyens L, Heimberg H, De Leu N.

Diabetologia. 2018 Aug;61(8):1804-1810. doi: 10.1007/s00125-018-4646-7. Epub 2018 May 22.


Generation of hepatocyte- and endocrine pancreatic-like cells from human induced endodermal progenitor cells.

Sambathkumar R, Akkerman R, Dastidar S, Roelandt P, Kumar M, Bajaj M, Mestre Rosa AR, Helsen N, Vanslembrouck V, Kalo E, Khurana S, Laureys J, Gysemans C, Faas MM, de Vos P, Verfaillie CM.

PLoS One. 2018 May 11;13(5):e0197046. doi: 10.1371/journal.pone.0197046. eCollection 2018.


Lactococcus lactis As a Versatile Vehicle for Tolerogenic Immunotherapy.

Cook DP, Gysemans C, Mathieu C.

Front Immunol. 2018 Jan 17;8:1961. doi: 10.3389/fimmu.2017.01961. eCollection 2017. Review.


Major depletion of SOX2+ stem cells in the adult pituitary is not restored which does not affect hormonal cell homeostasis and remodelling.

Roose H, Cox B, Boretto M, Gysemans C, Vennekens A, Vankelecom H.

Sci Rep. 2017 Dec 5;7(1):16940. doi: 10.1038/s41598-017-16796-2.


Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth.

Van Helleputte L, Kater M, Cook DP, Eykens C, Rossaert E, Haeck W, Jaspers T, Geens N, Vanden Berghe P, Gysemans C, Mathieu C, Robberecht W, Van Damme P, Cavaletti G, Jarpe M, Van Den Bosch L.

Neurobiol Dis. 2018 Mar;111:59-69. doi: 10.1016/j.nbd.2017.11.011. Epub 2017 Nov 29.


MIF inhibition interferes with the inflammatory and T cell-stimulatory capacity of NOD macrophages and delays autoimmune diabetes onset.

Korf H, Breser L, Van Hoeck J, Godoy J, Cook DP, Stijlemans B, De Smidt E, Moyson C, Monteiro Carvalho Mori Cunha JP, Rivero V, Gysemans C, Mathieu C.

PLoS One. 2017 Nov 2;12(11):e0187455. doi: 10.1371/journal.pone.0187455. eCollection 2017.


Regulation of Immune Function by Vitamin D and Its Use in Diseases of Immunity.

Vanherwegen AS, Gysemans C, Mathieu C.

Endocrinol Metab Clin North Am. 2017 Dec;46(4):1061-1094. doi: 10.1016/j.ecl.2017.07.010. Epub 2017 Oct 6. Review.


Differential transcriptome of tolerogenic versus inflammatory dendritic cells points to modulated T1D genetic risk and enriched immune regulation.

Nikolic T, Woittiez NJC, van der Slik A, Laban S, Joosten A, Gysemans C, Mathieu C, Zwaginga JJ, Koeleman B, Roep BO.

Genes Immun. 2017 Sep;18(3):176-183. doi: 10.1038/gene.2017.18. Epub 2017 Aug 10.


Impact on Experimental Colitis of Vitamin D Receptor Deletion in Intestinal Epithelial or Myeloid Cells.

Leyssens C, Verlinden L, De Hertogh G, Kato S, Gysemans C, Mathieu C, Carmeliet G, Verstuyf A.

Endocrinology. 2017 Jul 1;158(7):2354-2366. doi: 10.1210/en.2017-00139.


Vitamin D endocrinology on the cross-road between immunity and metabolism.

Vanherwegen AS, Gysemans C, Mathieu C.

Mol Cell Endocrinol. 2017 Sep 15;453:52-67. doi: 10.1016/j.mce.2017.04.018. Epub 2017 Apr 28. Review.


Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity.

Philippaert K, Pironet A, Mesuere M, Sones W, Vermeiren L, Kerselaers S, Pinto S, Segal A, Antoine N, Gysemans C, Laureys J, Lemaire K, Gilon P, Cuypers E, Tytgat J, Mathieu C, Schuit F, Rorsman P, Talavera K, Voets T, Vennekens R.

Nat Commun. 2017 Mar 31;8:14733. doi: 10.1038/ncomms14733.


Prospects of a type 1 diabetes vaccine.

Cook DP, Gysemans C, Mathieu C.

Expert Opin Biol Ther. 2017 Apr;17(4):403-406. doi: 10.1080/14712598.2017.1295035. Epub 2017 Feb 22. No abstract available.


Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10-Secreting Lactococcus lactis in Combination With Low-Dose Anti-CD3 Depends on the Induction of Foxp3-Positive T Cells.

Takiishi T, Cook DP, Korf H, Sebastiani G, Mancarella F, Cunha JP, Wasserfall C, Casares N, Lasarte JJ, Steidler L, Rottiers P, Dotta F, Gysemans C, Mathieu C.

Diabetes. 2017 Feb;66(2):448-459. doi: 10.2337/db15-1625. Epub 2016 Nov 8.


Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis.

Crèvecoeur I, Gudmundsdottir V, Vig S, Marques Câmara Sodré F, D'Hertog W, Fierro AC, Van Lommel L, Gysemans C, Marchal K, Waelkens E, Schuit F, Brunak S, Overbergh L, Mathieu C.

Diabetologia. 2017 Mar;60(3):475-489. doi: 10.1007/s00125-016-4191-1. Epub 2017 Jan 12.


Glibenclamide Prevents Diabetes in NOD Mice.

Lamprianou S, Gysemans C, Bou Saab J, Pontes H, Mathieu C, Meda P.

PLoS One. 2016 Dec 22;11(12):e0168839. doi: 10.1371/journal.pone.0168839. eCollection 2016.


Human multipotent adult progenitor cells enhance islet function and revascularisation when co-transplanted as a composite pellet in a mouse model of diabetes.

Cunha JP, Leuckx G, Sterkendries P, Korf H, Bomfim-Ferreira G, Overbergh L, Vaes B, Heimberg H, Gysemans C, Mathieu C.

Diabetologia. 2017 Jan;60(1):134-142. Epub 2016 Oct 4.


Vascular Endothelial Growth Factor Up-regulation in Human Amniotic Fluid Stem Cell Enhances Nephroprotection After Ischemia-Reperfusion Injury in the Rat.

Mori da Cunha MG, Zia S, Beckmann DV, Carlon MS, Arcolino FO, Albersen M, Pippi NL, Graça DL, Gysemans C, Carmeliet P, Levtchenko E, Deprest J, Toelen J.

Crit Care Med. 2017 Jan;45(1):e86-e96.


1,25-Dihydroxyvitamin D Modulates Antibacterial and Inflammatory Response in Human Cigarette Smoke-Exposed Macrophages.

Heulens N, Korf H, Mathyssen C, Everaerts S, De Smidt E, Dooms C, Yserbyt J, Gysemans C, Gayan-Ramirez G, Mathieu C, Janssens W.

PLoS One. 2016 Aug 11;11(8):e0160482. doi: 10.1371/journal.pone.0160482. eCollection 2016.

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