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Items: 1 to 20 of 61

1.

Huntingtin-interacting protein 1 (HIP1) regulates arthritis severity and synovial fibroblast invasiveness by altering PDGFR and Rac1 signalling.

Laragione T, Brenner M, Lahiri A, Gao E, Harris C, Gulko PS.

Ann Rheum Dis. 2018 Nov;77(11):1627-1635. doi: 10.1136/annrheumdis-2018-213498. Epub 2018 Jul 26.

PMID:
30049830
2.

Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes.

Ai R, Laragione T, Hammaker D, Boyle DL, Wildberg A, Maeshima K, Palescandolo E, Krishna V, Pocalyko D, Whitaker JW, Bai Y, Nagpal S, Bachman KE, Ainsworth RI, Wang M, Ding B, Gulko PS, Wang W, Firestein GS.

Nat Commun. 2018 May 15;9(1):1921. doi: 10.1038/s41467-018-04310-9.

3.

Targeting KCa1.1 Channels with a Scorpion Venom Peptide for the Therapy of Rat Models of Rheumatoid Arthritis.

Tanner MR, Pennington MW, Chamberlain BH, Huq R, Gehrmann EJ, Laragione T, Gulko PS, Beeton C.

J Pharmacol Exp Ther. 2018 May;365(2):227-236. doi: 10.1124/jpet.117.245118. Epub 2018 Feb 16.

PMID:
29453198
4.

Suppression and resolution of autoimmune arthritis by rhesus θ-defensin-1, an immunomodulatory macrocyclic peptide.

Schaal JB, Tran DQ, Subramanian A, Patel R, Laragione T, Roberts KD, Trinh K, Tongaonkar P, Tran PA, Minond D, Fields GB, Beringer P, Ouellette AJ, Gulko PS, Selsted ME.

PLoS One. 2017 Nov 16;12(11):e0187868. doi: 10.1371/journal.pone.0187868. eCollection 2017.

5.

Gastrin-releasing peptide and its receptor increase arthritis fibroblast-like synoviocytes invasiveness through activating the PI3K/AKT pathway.

Clarimundo VS, Farinon M, Pedó RT, Teixeira VON, Nör C, Gulko PS, Xavier RM, de Oliveira PG.

Peptides. 2017 Sep;95:57-61. doi: 10.1016/j.peptides.2017.07.008. Epub 2017 Jul 18.

6.

KCa1.1 channels regulate β1-integrin function and cell adhesion in rheumatoid arthritis fibroblast-like synoviocytes.

Tanner MR, Pennington MW, Laragione T, Gulko PS, Beeton C.

FASEB J. 2017 Aug;31(8):3309-3320. doi: 10.1096/fj.201601097R. Epub 2017 Apr 20.

7.

Short-term low-magnesium diet reduces autoimmune arthritis severity and synovial tissue gene expression.

Brenner M, Laragione T, Gulko PS.

Physiol Genomics. 2017 Apr 1;49(4):238-242. doi: 10.1152/physiolgenomics.00003.2017. Epub 2017 Mar 3.

PMID:
28258078
8.

Disease modifying anti-rheumatic activity of the alkaloid montanine on experimental arthritis and fibroblast-like synoviocytes.

Farinon M, Clarimundo VS, Pedrazza GP, Gulko PS, Zuanazzi JA, Xavier RM, de Oliveira PG.

Eur J Pharmacol. 2017 Mar 15;799:180-187. doi: 10.1016/j.ejphar.2017.02.013. Epub 2017 Feb 10.

9.

Erratum to: Different expression of β subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes.

Pethő Z, Tanner MR, Tajhya RB, Huq R, Laragione T, Panyi G, Gulko PS, Beeton C.

Arthritis Res Ther. 2016 Jun 1;18(1):122. No abstract available.

10.

Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat.

Tuncel J, Haag S, Hoffmann MH, Yau AC, Hultqvist M, Olofsson P, Bäcklund J, Nandakumar KS, Weidner D, Fischer A, Leichsenring A, Lange F, Haase C, Lu S, Gulko PS, Steiner G, Holmdahl R.

PLoS One. 2016 May 26;11(5):e0155936. doi: 10.1371/journal.pone.0155936. eCollection 2016.

11.

Different expression of β subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes.

Pethő Z, Tanner MR, Tajhya RB, Huq R, Laragione T, Panyi G, Gulko PS, Beeton C.

Arthritis Res Ther. 2016 May 10;18(1):103. doi: 10.1186/s13075-016-1003-4. Erratum in: Arthritis Res Ther. 2016;18(1):122.

12.

Rhesus macaque θ-defensin RTD-1 inhibits proinflammatory cytokine secretion and gene expression by inhibiting the activation of NF-κB and MAPK pathways.

Tongaonkar P, Trinh KK, Schaal JB, Tran D, Gulko PS, Ouellette AJ, Selsted ME.

J Leukoc Biol. 2015 Dec;98(6):1061-70. doi: 10.1189/jlb.3A0315-102R. Epub 2015 Aug 12.

13.

The cation channel Trpv2 is a new suppressor of arthritis severity, joint damage, and synovial fibroblast invasion.

Laragione T, Cheng KF, Tanner MR, He M, Beeton C, Al-Abed Y, Gulko PS.

Clin Immunol. 2015 Jun;158(2):183-92. doi: 10.1016/j.clim.2015.04.001. Epub 2015 Apr 11.

14.

KCa1.1 inhibition attenuates fibroblast-like synoviocyte invasiveness and ameliorates disease in rat models of rheumatoid arthritis.

Tanner MR, Hu X, Huq R, Tajhya RB, Sun L, Khan FS, Laragione T, Horrigan FT, Gulko PS, Beeton C.

Arthritis Rheumatol. 2015 Jan;67(1):96-106. doi: 10.1002/art.38883.

15.

Analyses of synovial tissues from arthritic and protected congenic rat strains reveal a new core set of genes associated with disease severity.

Brenner M, Laragione T, Gulko PS.

Physiol Genomics. 2013 Nov 15;45(22):1109-22. doi: 10.1152/physiolgenomics.00108.2013. Epub 2013 Sep 17.

16.

The multiple chemokine-binding bovine herpesvirus 1 glycoprotein G (BHV1gG) inhibits polymorphonuclear cell but not monocyte migration into inflammatory sites.

Liu Z, Bethunaickan R, Sahu R, Brenner M, Laragione T, Gulko PS, Davidson A.

Mol Med. 2013;19:276-85. doi: 10.2119/molmed.2013.00339.

17.

Arthritis severity locus Cia4 is an early regulator of IL-6, IL-1β, and NF-κB activators' expression in pristane-induced arthritis.

Brenner M, Laragione T, Gulko PS.

Physiol Genomics. 2013 Jul 2;45(13):552-64. doi: 10.1152/physiolgenomics.00029.2013. Epub 2013 May 21.

18.

Whole-genome sequences of DA and F344 rats with different susceptibilities to arthritis, autoimmunity, inflammation and cancer.

Guo X, Brenner M, Zhang X, Laragione T, Tai S, Li Y, Bu J, Yin Y, Shah AA, Kwan K, Li Y, Jun W, Gulko PS.

Genetics. 2013 Aug;194(4):1017-28. doi: 10.1534/genetics.113.153049. Epub 2013 May 20.

20.

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