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Items: 1 to 20 of 37

1.

Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells.

Estoppey D, Hewett JW, Guy CT, Harrington E, Thomas JR, Schirle M, Cuttat R, Waldt A, Gerrits B, Yang Z, Schuierer S, Pan X, Xie K, Carbone W, Knehr J, Lindeman A, Russ C, Frias E, Hoffman GR, Varadarajan M, Ramadan N, Reece-Hoyes JS, Wang Q, Chen X, McAllister G, Roma G, Bouwmeester T, Hoepfner D.

Sci Rep. 2017 Feb 16;7:42728. doi: 10.1038/srep42728.

2.

Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation.

Ginster S, Bardet M, Unterreiner A, Malinverni C, Renner F, Lam S, Freuler F, Gerrits B, Voshol J, Calzascia T, Régnier CH, Renatus M, Nikolay R, Israël L, Bornancin F.

PLoS One. 2017 Jan 4;12(1):e0169026. doi: 10.1371/journal.pone.0169026. eCollection 2017.

3.

Exploring Glucocorticoid Receptor Agonists Mechanism of Action Through Mass Cytometry and Radial Visualizations.

Abraham Y, Gerrits B, Ludwig MG, Rebhan M, Gubser Keller C.

Cytometry B Clin Cytom. 2017 Jan;92(1):42-56. doi: 10.1002/cyto.b.21499.

4.

Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation.

Geering B, Zokouri Z, Hürlemann S, Gerrits B, Ausländer D, Britschgi A, Tschan MP, Simon HU, Fussenegger M.

Mol Cell Biol. 2015 Oct 19;36(1):132-43. doi: 10.1128/MCB.00515-15. Print 2016 Jan 1.

5.

Surfaceome of classical Hodgkin and non-Hodgkin lymphoma.

Hofmann A, Thiesler T, Gerrits B, Behnke S, Sobotzki N, Omasits U, Bausch-Fluck D, Bock T, Aebersold R, Moch H, Tinguely M, Wollscheid B.

Proteomics Clin Appl. 2015 Aug;9(7-8):661-70. doi: 10.1002/prca.201400146.

6.

Chemical genetic approach identifies microtubule affinity-regulating kinase 1 as a leucine-rich repeat kinase 2 substrate.

Krumova P, Reyniers L, Meyer M, Lobbestael E, Stauffer D, Gerrits B, Muller L, Hoving S, Kaupmann K, Voshol J, Fabbro D, Bauer A, Rovelli G, Taymans JM, Bouwmeester T, Baekelandt V.

FASEB J. 2015 Jul;29(7):2980-92. doi: 10.1096/fj.14-262329. Epub 2015 Apr 8.

PMID:
25854701
7.

Scalable production in human cells and biochemical characterization of full-length normal and mutant huntingtin.

Huang B, Lucas T, Kueppers C, Dong X, Krause M, Bepperling A, Buchner J, Voshol H, Weiss A, Gerrits B, Kochanek S.

PLoS One. 2015 Mar 23;10(3):e0121055. doi: 10.1371/journal.pone.0121055. eCollection 2015.

8.

Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.

Thompson JW, Nagel J, Hoving S, Gerrits B, Bauer A, Thomas JR, Kirschner MW, Schirle M, Luchansky SJ.

J Biol Chem. 2014 Oct 17;289(42):28942-55. doi: 10.1074/jbc.M114.573352. Epub 2014 Aug 21.

9.

Prolyl isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection.

Steger M, Murina O, Hühn D, Ferretti LP, Walser R, Hänggi K, Lafranchi L, Neugebauer C, Paliwal S, Janscak P, Gerrits B, Del Sal G, Zerbe O, Sartori AA.

Mol Cell. 2013 May 9;50(3):333-43. doi: 10.1016/j.molcel.2013.03.023. Epub 2013 Apr 25.

10.

Protein complex interactor analysis and differential activity of KDM3 subfamily members towards H3K9 methylation.

Brauchle M, Yao Z, Arora R, Thigale S, Clay I, Inverardi B, Fletcher J, Taslimi P, Acker MG, Gerrits B, Voshol J, Bauer A, Schübeler D, Bouwmeester T, Ruffner H.

PLoS One. 2013 Apr 11;8(4):e60549. doi: 10.1371/journal.pone.0060549. Print 2013.

11.

Extracellular signal-regulated kinase and glycogen synthase kinase 3β regulate gephyrin postsynaptic aggregation and GABAergic synaptic function in a calpain-dependent mechanism.

Tyagarajan SK, Ghosh H, Yévenes GE, Imanishi SY, Zeilhofer HU, Gerrits B, Fritschy JM.

J Biol Chem. 2013 Apr 5;288(14):9634-47. doi: 10.1074/jbc.M112.442616. Epub 2013 Feb 13.

12.

Comparative phosphoproteome profiling reveals a function of the STN8 kinase in fine-tuning of cyclic electron flow (CEF).

Reiland S, Finazzi G, Endler A, Willig A, Baerenfaller K, Grossmann J, Gerrits B, Rutishauser D, Gruissem W, Rochaix JD, Baginsky S.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12955-60. doi: 10.1073/pnas.1104734108. Epub 2011 Jul 18.

13.

Proteome profiling suggests a pro-inflammatory role for plasma cells through release of high-mobility group box 1 protein.

Vettermann C, Castor D, Mekker A, Gerrits B, Karas M, Jäck HM.

Proteomics. 2011 Apr;11(7):1228-37. doi: 10.1002/pmic.201000491. Epub 2011 Feb 14.

PMID:
21319304
14.

Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast.

Bodenmiller B, Wanka S, Kraft C, Urban J, Campbell D, Pedrioli PG, Gerrits B, Picotti P, Lam H, Vitek O, Brusniak MY, Roschitzki B, Zhang C, Shokat KM, Schlapbach R, Colman-Lerner A, Nolan GP, Nesvizhskii AI, Peter M, Loewith R, von Mering C, Aebersold R.

Sci Signal. 2010 Dec 21;3(153):rs4. doi: 10.1126/scisignal.2001182.

15.

Regulation of GABAergic synapse formation and plasticity by GSK3beta-dependent phosphorylation of gephyrin.

Tyagarajan SK, Ghosh H, Yévenes GE, Nikonenko I, Ebeling C, Schwerdel C, Sidler C, Zeilhofer HU, Gerrits B, Muller D, Fritschy JM.

Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):379-84. doi: 10.1073/pnas.1011824108. Epub 2010 Dec 20.

16.

Molecular characterization of a trafficking organelle: dissecting the axonal paths of calsyntenin-1 transport vesicles.

Steuble M, Gerrits B, Ludwig A, Mateos JM, Diep TM, Tagaya M, Stephan A, Schätzle P, Kunz B, Streit P, Sonderegger P.

Proteomics. 2010 Nov;10(21):3775-88. doi: 10.1002/pmic.201000384.

PMID:
20925061
17.

Transcriptional profiling of ErbB signalling in mammary luminal epithelial cells--interplay of ErbB and IGF1 signalling through IGFBP3 regulation.

Worthington J, Bertani M, Chan HL, Gerrits B, Timms JF.

BMC Cancer. 2010 Sep 14;10:490. doi: 10.1186/1471-2407-10-490.

18.

Mapping of phosphorylation sites by LC-MS/MS.

Gerrits B, Bodenmiller B.

Methods Mol Biol. 2010;658:127-36. doi: 10.1007/978-1-60761-780-8_7.

PMID:
20839101
19.

Proteomic cell surface phenotyping of differentiating acute myeloid leukemia cells.

Hofmann A, Gerrits B, Schmidt A, Bock T, Bausch-Fluck D, Aebersold R, Wollscheid B.

Blood. 2010 Sep 30;116(13):e26-34. doi: 10.1182/blood-2010-02-271270. Epub 2010 Jun 22.

20.

Proteome analysis of fungal and bacterial involvement in leaf litter decomposition.

Schneider T, Gerrits B, Gassmann R, Schmid E, Gessner MO, Richter A, Battin T, Eberl L, Riedel K.

Proteomics. 2010 May;10(9):1819-30. doi: 10.1002/pmic.200900691.

PMID:
20198641

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