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Removal of clock gene Bmal1 from the retina affects retinal development and accelerates cone photoreceptor degeneration during aging.

Baba K, Piano I, Lyuboslavsky P, Chrenek MA, Sellers JT, Zhang S, Gargini C, He L, Tosini G, Iuvone PM.

Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):13099-13104. doi: 10.1073/pnas.1808137115. Epub 2018 Nov 29.


Melatonin partially protects 661W cells from H2O2-induced death by inhibiting Fas/FasL-caspase-3.

Sánchez-Bretaño A, Baba K, Janjua U, Piano I, Gargini C, Tosini G.

Mol Vis. 2017 Dec 3;23:844-852. eCollection 2017.


Connexin 36 expression is required for electrical coupling between mouse rods and cones.

Asteriti S, Gargini C, Cangiano L.

Vis Neurosci. 2017 Jan;34:E006. doi: 10.1017/S0952523817000037.


Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects.

Barresi E, Nesi G, Citi V, Piragine E, Piano I, Taliani S, Da Settimo F, Rapposelli S, Testai L, Breschi MC, Gargini C, Calderone V, Martelli A.

J Med Chem. 2017 Sep 14;60(17):7512-7523. doi: 10.1021/acs.jmedchem.7b00888. Epub 2017 Aug 25.


Pattern of retinal morphological and functional decay in a light-inducible, rhodopsin mutant mouse.

Gargini C, Novelli E, Piano I, Biagioni M, Strettoi E.

Sci Rep. 2017 Jul 18;7(1):5730. doi: 10.1038/s41598-017-06045-x.


Application of An Improved HPLC-FL Method to Screen Serine Palmitoyl Transferase Inhibitors.

Bertini S, Saccomanni G, Carlo SD, Digiacomo M, Gargini C, Piano I, Campisi GM, Ghidoni R, Macchia M, Manera C.

Molecules. 2017 Jul 17;22(7). pii: E1198. doi: 10.3390/molecules22071198.


The Citrus Flavanone Naringenin Produces Cardioprotective Effects in Hearts from 1 Year Old Rat, through Activation of mitoBK Channels.

Testai L, Da Pozzo E, Piano I, Pistelli L, Gargini C, Breschi MC, Braca A, Martini C, Martelli A, Calderone V.

Front Pharmacol. 2017 Feb 27;8:71. doi: 10.3389/fphar.2017.00071. eCollection 2017.


Corrigendum: The bacterial toxin CNF1 as a tool to induce retinal degeneration reminiscent of retinitis pigmentosa.

Guadagni V, Cerri C, Piano I, Novelli E, Gargini C, Fiorentini C, Caleo M, Strettoi E.

Sci Rep. 2016 Dec 9;6:37882. doi: 10.1038/srep37882. No abstract available.


The bacterial toxin CNF1 as a tool to induce retinal degeneration reminiscent of retinitis pigmentosa.

Guadagni V, Cerri C, Piano I, Novelli E, Gargini C, Fiorentini C, Caleo M, Strettoi E.

Sci Rep. 2016 Oct 24;6:35919. doi: 10.1038/srep35919. Erratum in: Sci Rep. 2016 Dec 09;6:37882.


The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress.

Testai L, Marino A, Piano I, Brancaleone V, Tomita K, Di Cesare Mannelli L, Martelli A, Citi V, Breschi MC, Levi R, Gargini C, Bucci M, Cirino G, Ghelardini C, Calderone V.

Pharmacol Res. 2016 Nov;113(Pt A):290-299. doi: 10.1016/j.phrs.2016.09.006. Epub 2016 Sep 9.


Involvement of Autophagic Pathway in the Progression of Retinal Degeneration in a Mouse Model of Diabetes.

Piano I, Novelli E, Della Santina L, Strettoi E, Cervetto L, Gargini C.

Front Cell Neurosci. 2016 Feb 19;10:42. doi: 10.3389/fncel.2016.00042. eCollection 2016.


TMEM16A is associated with voltage-gated calcium channels in mouse retina and its function is disrupted upon mutation of the auxiliary α2δ4 subunit.

Caputo A, Piano I, Demontis GC, Bacchi N, Casarosa S, Della Santina L, Gargini C.

Front Cell Neurosci. 2015 Oct 21;9:422. doi: 10.3389/fncel.2015.00422. eCollection 2015.


Pharmacological approaches to retinitis pigmentosa: A laboratory perspective.

Guadagni V, Novelli E, Piano I, Gargini C, Strettoi E.

Prog Retin Eye Res. 2015 Sep;48:62-81. doi: 10.1016/j.preteyeres.2015.06.005. Epub 2015 Jun 22. Review.


Different patterns of H2S/NO activity and cross-talk in the control of the coronary vascular bed under normotensive or hypertensive conditions.

Testai L, D'Antongiovanni V, Piano I, Martelli A, Citi V, Duranti E, Virdis A, Blandizzi C, Gargini C, Breschi MC, Calderone V.

Nitric Oxide. 2015 May 1;47:25-33. doi: 10.1016/j.niox.2015.03.003. Epub 2015 Mar 17.


Altered protease-activated receptor-1 expression and signaling in a malignant pleural mesothelioma cell line, NCI-H28, with homozygous deletion of the β-catenin gene.

Fazzini A, D'Antongiovanni V, Giusti L, Da Valle Y, Ciregia F, Piano I, Caputo A, D'Ursi AM, Gargini C, Lucacchini A, Mazzoni MR.

PLoS One. 2014 Nov 3;9(11):e111550. doi: 10.1371/journal.pone.0111550. eCollection 2014.


First evidence of TRPV5 and TRPV6 channels in human parathyroid glands: possible involvement in neoplastic transformation.

Giusti L, Cetani F, Da Valle Y, Pardi E, Ciregia F, Donadio E, Gargini C, Piano I, Borsari S, Jaber A, Caputo A, Basolo F, Giannaccini G, Marcocci C, Lucacchini A.

J Cell Mol Med. 2014 Oct;18(10):1944-52. doi: 10.1111/jcmm.12372. Epub 2014 Aug 28.


Mouse rods signal through gap junctions with cones.

Asteriti S, Gargini C, Cangiano L.

Elife. 2014;3:e01386. doi: 10.7554/eLife.01386. Epub 2014 Jan 7.


Cone survival and preservation of visual acuity in an animal model of retinal degeneration.

Piano I, Novelli E, Gasco P, Ghidoni R, Strettoi E, Gargini C.

Eur J Neurosci. 2013 Jun;37(11):1853-62. doi: 10.1111/ejn.12196. Epub 2013 Apr 2.


Serotonin receptor of type 6 (5-HT6) in human prefrontal cortex and hippocampus post-mortem: an immunohistochemical and immunofluorescence study.

Marazziti D, Baroni S, Pirone A, Giannaccini G, Betti L, Testa G, Schmid L, Palego L, Borsini F, Bordi F, Piano I, Gargini C, Castagna M, Catena-Dell'osso M, Lucacchini A.

Neurochem Int. 2013 Jan;62(2):182-8. doi: 10.1016/j.neuint.2012.11.013. Epub 2012 Dec 3.


Environmental enrichment extends photoreceptor survival and visual function in a mouse model of retinitis pigmentosa.

Barone I, Novelli E, Piano I, Gargini C, Strettoi E.

PLoS One. 2012;7(11):e50726. doi: 10.1371/journal.pone.0050726. Epub 2012 Nov 28.

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