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Items: 1 to 20 of 45


Obesity and High-Fat Diet Induce Distinct Changes in Placental Gene Expression and Pregnancy Outcome.

Mahany EB, Han X, Borges BC, da Silveira Cruz-Machado S, Allen SJ, Garcia-Galiano D, Hoenerhoff MJ, Bellefontaine NH, Elias CF.

Endocrinology. 2018 Apr 1;159(4):1718-1733. doi: 10.1210/en.2017-03053.


PI3Kα inactivation in leptin receptor cells increases leptin sensitivity but disrupts growth and reproduction.

Garcia-Galiano D, Borges BC, Donato J Jr, Allen SJ, Bellefontaine N, Wang M, Zhao JJ, Kozloff KM, Hill JW, Elias CF.

JCI Insight. 2017 Dec 7;2(23). pii: 96728. doi: 10.1172/jci.insight.96728. [Epub ahead of print]


Obesity-Induced Infertility in Male Mice Is Associated With Disruption of Crisp4 Expression and Sperm Fertilization Capacity.

Borges BC, Garcia-Galiano D, da Silveira Cruz-Machado S, Han X, Gavrilina GB, Saunders TL, Auchus RJ, Hammoud SS, Smith GD, Elias CF.

Endocrinology. 2017 Sep 1;158(9):2930-2943. doi: 10.1210/en.2017-00295.


Sexually dimorphic distribution of Prokr2 neurons revealed by the Prokr2-Cre mouse model.

Mohsen Z, Sim H, Garcia-Galiano D, Han X, Bellefontaine N, Saunders TL, Elias CF.

Brain Struct Funct. 2017 Dec;222(9):4111-4129. doi: 10.1007/s00429-017-1456-5. Epub 2017 Jun 14.


Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons.

Cady G, Landeryou T, Garratt M, Kopchick JJ, Qi N, Garcia-Galiano D, Elias CF, Myers MG Jr, Miller RA, Sandoval DA, Sadagurski M.

Mol Metab. 2017 Mar 16;6(5):393-405. doi: 10.1016/j.molmet.2017.03.001. eCollection 2017 May.


AMPKα2 in Kiss1 Neurons Is Required for Reproductive Adaptations to Acute Metabolic Challenges in Adult Female Mice.

Torsoni MA, Borges BC, Cote JL, Allen SJ, Mahany E, Garcia-Galiano D, Elias CF.

Endocrinology. 2016 Dec;157(12):4803-4816. Epub 2016 Oct 12.


Defining a novel leptin-melanocortin-kisspeptin pathway involved in the metabolic control of puberty.

Manfredi-Lozano M, Roa J, Ruiz-Pino F, Piet R, Garcia-Galiano D, Pineda R, Zamora A, Leon S, Sanchez-Garrido MA, Romero-Ruiz A, Dieguez C, Vazquez MJ, Herbison AE, Pinilla L, Tena-Sempere M.

Mol Metab. 2016 Aug 11;5(10):844-857. doi: 10.1016/j.molmet.2016.08.003. eCollection 2016 Oct.


Hypothalamic action of phoenixin to control reproductive hormone secretion in females: importance of the orphan G protein-coupled receptor Gpr173.

Stein LM, Tullock CW, Mathews SK, Garcia-Galiano D, Elias CF, Samson WK, Yosten GL.

Am J Physiol Regul Integr Comp Physiol. 2016 Sep 1;311(3):R489-96. doi: 10.1152/ajpregu.00191.2016. Epub 2016 Jul 20.


PI3K p110β subunit in leptin receptor expressing cells is required for the acute hypophagia induced by endotoxemia.

Borges BC, Garcia-Galiano D, Rorato R, Elias LLK, Elias CF.

Mol Metab. 2016 Mar 19;5(6):379-391. doi: 10.1016/j.molmet.2016.03.003. eCollection 2016 Jun.


Leptin receptor null mice with reexpression of LepR in GnRHR expressing cells display elevated FSH levels but remain in a prepubertal state.

Allen SJ, Garcia-Galiano D, Borges BC, Burger LL, Boehm U, Elias CF.

Am J Physiol Regul Integr Comp Physiol. 2016 Jun 1;310(11):R1258-66. doi: 10.1152/ajpregu.00529.2015. Epub 2016 Apr 13.


Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity.

León S, Barroso A, Vázquez MJ, García-Galiano D, Manfredi-Lozano M, Ruiz-Pino F, Heras V, Romero-Ruiz A, Roa J, Schutz G, Kirilov M, Gaytan F, Pinilla L, Tena-Sempere M.

Sci Rep. 2016 Jan 12;6:19206. doi: 10.1038/srep19206.


Crowding and Follicular Fate: Spatial Determinants of Follicular Reserve and Activation of Follicular Growth in the Mammalian Ovary.

Gaytan F, Morales C, Leon S, Garcia-Galiano D, Roa J, Tena-Sempere M.

PLoS One. 2015 Dec 7;10(12):e0144099. doi: 10.1371/journal.pone.0144099. eCollection 2015.


Effects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult rats.

Ruiz-Pino F, Garcia-Galiano D, Manfredi-Lozano M, Leon S, Sánchez-Garrido MA, Roa J, Pinilla L, Navarro VM, Tena-Sempere M.

Endocrinology. 2015 Feb;156(2):576-88. doi: 10.1210/en.2014-1026. Epub 2014 Dec 9.


Role of the adipocyte-derived hormone leptin in reproductive control.

Garcia-Galiano D, Allen SJ, Elias CF.

Horm Mol Biol Clin Investig. 2014 Sep;19(3):141-9. doi: 10.1515/hmbci-2014-0017. Review.


Kisspeptin receptor haplo-insufficiency causes premature ovarian failure despite preserved gonadotropin secretion.

Gaytan F, Garcia-Galiano D, Dorfman MD, Manfredi-Lozano M, Castellano JM, Dissen GA, Ojeda SR, Tena-Sempere M.

Endocrinology. 2014 Aug;155(8):3088-97. doi: 10.1210/en.2014-1110. Epub 2014 Jun 2. Erratum in: Endocrinology. 2015 Sep;156(9):3402.


Loss of Ntrk2/Kiss1r signaling in oocytes causes premature ovarian failure.

Dorfman MD, Garcia-Rudaz C, Alderman Z, Kerr B, Lomniczi A, Dissen GA, Castellano JM, Garcia-Galiano D, Gaytan F, Xu B, Tena-Sempere M, Ojeda SR.

Endocrinology. 2014 Aug;155(8):3098-111. doi: 10.1210/en.2014-1111. Epub 2014 May 30.


Physiological roles of gonadotropin-inhibitory hormone signaling in the control of mammalian reproductive axis: studies in the NPFF1 receptor null mouse.

León S, García-Galiano D, Ruiz-Pino F, Barroso A, Manfredi-Lozano M, Romero-Ruiz A, Roa J, Vázquez MJ, Gaytan F, Blomenrohr M, van Duin M, Pinilla L, Tena-Sempere M.

Endocrinology. 2014 Aug;155(8):2953-65. doi: 10.1210/en.2014-1030. Epub 2014 May 13.


Obesity-induced hypogonadism in the male: premature reproductive neuroendocrine senescence and contribution of Kiss1-mediated mechanisms.

Sánchez-Garrido MA, Ruiz-Pino F, Manfredi-Lozano M, Leon S, Garcia-Galiano D, Castaño JP, Luque RM, Romero-Ruiz A, Castellano JM, Diéguez C, Pinilla L, Tena-Sempere M.

Endocrinology. 2014 Mar;155(3):1067-79. doi: 10.1210/en.2013-1584. Epub 2014 Jan 1.


Metabolic programming of puberty: sexually dimorphic responses to early nutritional challenges.

Sánchez-Garrido MA, Castellano JM, Ruiz-Pino F, Garcia-Galiano D, Manfredi-Lozano M, Leon S, Romero-Ruiz A, Diéguez C, Pinilla L, Tena-Sempere M.

Endocrinology. 2013 Sep;154(9):3387-400. doi: 10.1210/en.2012-2157. Epub 2013 Jun 10.


Emerging roles of NUCB2/nesfatin-1 in the metabolic control of reproduction.

García-Galiano D, Tena-Sempere M.

Curr Pharm Des. 2013;19(39):6966-72. Review.


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