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Items: 1 to 20 of 24

1.

Growth Hormone-Releasing Hormone in Diabetes.

Fridlyand LE, Tamarina NA, Schally AV, Philipson LH.

Front Endocrinol (Lausanne). 2016 Oct 10;7:129. eCollection 2016. Review.

2.

Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis.

Fridlyand LE, Philipson LH.

PLoS One. 2016 May 3;11(5):e0152869. doi: 10.1371/journal.pone.0152869. eCollection 2016.

3.

Ion channels and regulation of insulin secretion in human β-cells: a computational systems analysis.

Fridlyand LE, Jacobson DA, Philipson LH.

Islets. 2013 Jan-Feb;5(1):1-15. doi: 10.4161/isl.24166. Review.

4.

A computational systems analysis of factors regulating α cell glucagon secretion.

Fridlyand LE, Philipson LH.

Islets. 2012 Jul-Aug;4(4):262-83. doi: 10.4161/isl.22193. Epub 2012 Jul 1.

5.

Coupling of metabolic, second messenger pathways and insulin granule dynamics in pancreatic beta-cells: a computational analysis.

Fridlyand LE, Philipson LH.

Prog Biophys Mol Biol. 2011 Nov;107(2):293-303. doi: 10.1016/j.pbiomolbio.2011.09.001. Epub 2011 Sep 8. Review.

6.

Mechanisms of glucose sensing in the pancreatic β-cell: A computational systems-based analysis.

Fridlyand LE, Phillipson LH.

Islets. 2011 Sep-Oct;3(5):224-30. Epub 2011 Sep 1. Review.

7.

Bursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms.

Fridlyand LE, Tamarina N, Philipson LH.

Am J Physiol Endocrinol Metab. 2010 Oct;299(4):E517-32. doi: 10.1152/ajpendo.00177.2010. Epub 2010 Jul 13. Review.

8.

Glucose sensing in the pancreatic beta cell: a computational systems analysis.

Fridlyand LE, Philipson LH.

Theor Biol Med Model. 2010 May 24;7:15. doi: 10.1186/1742-4682-7-15.

9.

A model of action potentials and fast Ca2+ dynamics in pancreatic beta-cells.

Fridlyand LE, Jacobson DA, Kuznetsov A, Philipson LH.

Biophys J. 2009 Apr 22;96(8):3126-39. doi: 10.1016/j.bpj.2009.01.029.

10.

Reactive species, cellular repair and risk factors in the onset of type 2 diabetes mellitus: review and hypothesis.

Fridlyand LE, Philipson LH.

Curr Diabetes Rev. 2006 May;2(2):241-59. Review.

PMID:
18220630
11.

Regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach.

Fridlyand LE, Harbeck MC, Roe MW, Philipson LH.

Am J Physiol Cell Physiol. 2007 Dec;293(6):C1924-33. Epub 2007 Oct 10.

12.

Cold climate genes and the prevalence of type 2 diabetes mellitus.

Fridlyand LE, Philipson LH.

Med Hypotheses. 2006;67(5):1034-41. Epub 2006 Jun 23. Review.

PMID:
16797871
13.

Oxidative reactive species in cell injury: Mechanisms in diabetes mellitus and therapeutic approaches.

Fridlyand LE, Philipson LH.

Ann N Y Acad Sci. 2005 Dec;1066:136-51. Review.

PMID:
16533924
14.

Reactive species and early manifestation of insulin resistance in type 2 diabetes.

Fridlyand LE, Philipson LH.

Diabetes Obes Metab. 2006 Mar;8(2):136-45. Review.

PMID:
16448517
15.

Delayed-rectifier (KV2.1) regulation of pancreatic beta-cell calcium responses to glucose: inhibitor specificity and modeling.

Tamarina NA, Kuznetsov A, Fridlyand LE, Philipson LH.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E578-85. Epub 2005 Jul 12.

16.

Adenine nucleotide regulation in pancreatic beta-cells: modeling of ATP/ADP-Ca2+ interactions.

Fridlyand LE, Ma L, Philipson LH.

Am J Physiol Endocrinol Metab. 2005 Nov;289(5):E839-48. Epub 2005 Jun 28.

17.
18.

Modeling of Ca2+ flux in pancreatic beta-cells: role of the plasma membrane and intracellular stores.

Fridlyand LE, Tamarina N, Philipson LH.

Am J Physiol Endocrinol Metab. 2003 Jul;285(1):E138-54. Epub 2003 Mar 18.

19.

Regulation in metabolic systems under homeostatic flux control.

Fridlyand LE, Scheibe R.

Arch Biochem Biophys. 2000 Feb 15;374(2):198-206.

PMID:
10666298
20.

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