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Items: 1 to 20 of 225

1.

Serine Protease Catalysis: A Computational Study of Tetrahedral Intermediates and Inhibitory Adducts.

Ngo PD, Mansoorabadi SO, Frey PA.

J Phys Chem B. 2016 Aug 4;120(30):7353-9. doi: 10.1021/acs.jpcb.6b04089. Epub 2016 Jul 25.

PMID:
27387593
2.

Transient intermediates in enzymology, 1964-2008.

Frey PA.

J Biol Chem. 2015 Apr 24;290(17):10610-26. doi: 10.1074/jbc.X115.650879. Epub 2015 Mar 9. No abstract available.

3.

Advances in research on metalloproteins.

Frey PA.

Methods Mol Biol. 2014;1122:1-3. doi: 10.1007/978-1-62703-794-5_1.

PMID:
24639249
4.

Travels with carbon-centered radicals. 5'-deoxyadenosine and 5'-deoxyadenosine-5'-yl in radical enzymology.

Frey PA.

Acc Chem Res. 2014 Feb 18;47(2):540-9. doi: 10.1021/ar400194k. Epub 2013 Dec 5.

PMID:
24308628
5.

Chemical and stereochemical actions of UDP-galactose 4-epimerase.

Frey PA, Hegeman AD.

Acc Chem Res. 2013 Jul 16;46(7):1417-26. doi: 10.1021/ar300246k. Epub 2013 Jan 23. Review.

PMID:
23339688
7.

The ubiquity of iron.

Frey PA, Reed GH.

ACS Chem Biol. 2012 Sep 21;7(9):1477-81. Epub 2012 Aug 27.

PMID:
22845493
8.

Radical stabilization is crucial in the mechanism of action of lysine 5,6-aminomutase: role of tyrosine-263α as revealed by electron paramagnetic resonance spectroscopy.

Chen YH, Maity AN, Pan YC, Frey PA, Ke SC.

J Am Chem Soc. 2011 Nov 2;133(43):17152-5. doi: 10.1021/ja207766c. Epub 2011 Oct 12.

PMID:
21939264
9.

Pyridoxal-5'-phosphate as the catalyst for radical isomerization in reactions of PLP-dependent aminomutases.

Frey PA, Reed GH.

Biochim Biophys Acta. 2011 Nov;1814(11):1548-57. doi: 10.1016/j.bbapap.2011.03.005. Epub 2011 Mar 22. Review.

PMID:
21435400
10.

Forging ahead: new mechanistic insights into iron biochemistry.

Frey PA, Outten CE.

Curr Opin Chem Biol. 2011 Apr;15(2):257-9. doi: 10.1016/j.cbpa.2011.02.022. Epub 2011 Mar 14. No abstract available.

PMID:
21411359
11.

Kinetic and spectroscopic evidence of negative cooperativity in the action of lysine 2,3-aminomutase.

Ruzicka FJ, Frey PA.

J Phys Chem B. 2010 Dec 16;114(49):16118-24. doi: 10.1021/jp103856m. Epub 2010 Jul 7.

12.

Climate change and the integrity of science.

Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J Jr, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS 3rd, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB Jr, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE Jr, Wu C, Wunsch C, Zoback ML.

Science. 2010 May 7;328(5979):689-90. doi: 10.1126/science.328.5979.689. No abstract available. Erratum in: Science. 2010 May 14;328(5980):826.

13.

Evidence for conformational movement and radical mechanism in the reaction of 4-thia-L-lysine with lysine 5,6-aminomutase.

Maity AN, Hsieh CP, Huang MH, Chen YH, Tang KH, Behshad E, Frey PA, Ke SC.

J Phys Chem B. 2009 Sep 10;113(36):12161-3. doi: 10.1021/jp905357a.

PMID:
19685884
14.

Radical triplets and suicide inhibition in reactions of 4-thia-D- and 4-thia-L-lysine with lysine 5,6-aminomutase.

Tang KH, Mansoorabadi SO, Reed GH, Frey PA.

Biochemistry. 2009 Sep 1;48(34):8151-60. doi: 10.1021/bi900828f.

15.

Cloning, expression, purification, cofactor requirements, and steady state kinetics of phosphoketolase-2 from Lactobacillus plantarum.

Yevenes A, Frey PA.

Bioorg Chem. 2008 Jun;36(3):121-7. doi: 10.1016/j.bioorg.2008.03.002. Epub 2008 Apr 21.

PMID:
18430452
16.

The Radical SAM Superfamily.

Frey PA, Hegeman AD, Ruzicka FJ.

Crit Rev Biochem Mol Biol. 2008 Jan-Feb;43(1):63-88. doi: 10.1080/10409230701829169 . Review.

PMID:
18307109
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