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Items: 1 to 20 of 62


Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.

Hewings DS, Heideker J, Ma TP, AhYoung AP, El Oualid F, Amore A, Costakes GT, Kirchhofer D, Brasher B, Pillow T, Popovych N, Maurer T, Schwerdtfeger C, Forrest WF, Yu K, Flygare J, Bogyo M, Wertz IE.

Nat Commun. 2018 Mar 21;9(1):1162. doi: 10.1038/s41467-018-03511-6.


Introducing People-Centered Language to SLEEP.

Buysse DJ, Parthasarathy S, Flygare J.

Sleep. 2017 Apr 1;40(4). doi: 10.1093/sleep/zsx038. No abstract available.


Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia.

Debnath S, Jaako P, Siva K, Rothe M, Chen J, Dahl M, Gaspar HB, Flygare J, Schambach A, Karlsson S.

Mol Ther. 2017 Aug 2;25(8):1805-1814. doi: 10.1016/j.ymthe.2017.04.002. Epub 2017 Apr 20.


Direct lineage reprogramming: a useful addition to the blood cell research toolbox.

Capellera-Garcia S, Flygare J.

Expert Rev Hematol. 2017 Feb;10(2):107-109. doi: 10.1080/17474086.2017.1272409. Epub 2017 Jan 5. No abstract available.


Listening to the Patient Voice in Narcolepsy: Diagnostic Delay, Disease Burden, and Treatment Efficacy.

Maski K, Steinhart E, Williams D, Scammell T, Flygare J, McCleary K, Gow M.

J Clin Sleep Med. 2017 Mar 15;13(3):419-425. doi: 10.5664/jcsm.6494.


Direct Conversion of Fibroblasts to Megakaryocyte Progenitors.

Pulecio J, Alejo-Valle O, Capellera-Garcia S, Vitaloni M, Rio P, Mejía-Ramírez E, Caserta I, Bueren JA, Flygare J, Raya A.

Cell Rep. 2016 Oct 11;17(3):671-683. doi: 10.1016/j.celrep.2016.09.036.


Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion.

Capellera-Garcia S, Pulecio J, Dhulipala K, Siva K, Rayon-Estrada V, Singbrant S, Sommarin MN, Walkley CR, Soneji S, Karlsson G, Raya Á, Sankaran VG, Flygare J.

Cell Rep. 2016 Jun 14;15(11):2550-62. doi: 10.1016/j.celrep.2016.05.027. Epub 2016 Jun 2.


Targeting LGR5+ cells with an antibody-drug conjugate for the treatment of colon cancer.

Junttila MR, Mao W, Wang X, Wang BE, Pham T, Flygare J, Yu SF, Yee S, Goldenberg D, Fields C, Eastham-Anderson J, Singh M, Vij R, Hongo JA, Firestein R, Schutten M, Flagella K, Polakis P, Polson AG.

Sci Transl Med. 2015 Nov 18;7(314):314ra186. doi: 10.1126/scitranslmed.aac7433.


FTY720 (Fingolimod) sensitizes hepatocellular carcinoma cells to sorafenib-mediated cytotoxicity.

Ahmed D, de Verdier PJ, Ryk C, Lunqe O, Stål P, Flygare J.

Pharmacol Res Perspect. 2015 Oct;3(5):e00171. doi: 10.1002/prp2.171. Epub 2015 Aug 19.


Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.

Sjögren SE, Siva K, Soneji S, George AJ, Winkler M, Jaako P, Wlodarski M, Karlsson S, Hannan RD, Flygare J.

Br J Haematol. 2015 Nov;171(4):517-29. doi: 10.1111/bjh.13632. Epub 2015 Aug 25.


Influence of rimonabant treatment on peripheral blood mononuclear cells; flow cytometry analysis and gene expression profiling.

Almestrand S, Wang X, Jeppsson-Ahlberg Å, Nordgren M, Flygare J, Christensson B, Rössner S, Sander B.

PeerJ. 2015 Jun 30;3:e1056. doi: 10.7717/peerj.1056. eCollection 2015.


Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia.

Jaako P, Debnath S, Olsson K, Zhang Y, Flygare J, Lindström MS, Bryder D, Karlsson S.

Leukemia. 2015 Nov;29(11):2221-9. doi: 10.1038/leu.2015.128. Epub 2015 May 19.


A Novel Anti-CD22 Anthracycline-Based Antibody-Drug Conjugate (ADC) That Overcomes Resistance to Auristatin-Based ADCs.

Yu SF, Zheng B, Go M, Lau J, Spencer S, Raab H, Soriano R, Jhunjhunwala S, Cohen R, Caruso M, Polakis P, Flygare J, Polson AG.

Clin Cancer Res. 2015 Jul 15;21(14):3298-306. doi: 10.1158/1078-0432.CCR-14-2035. Epub 2015 Apr 3.


Perturbations of the endocannabinoid system in mantle cell lymphoma: correlations to clinical and pathological features.

Wasik AM, Nygren L, Almestrand S, Zong F, Flygare J, Wennerholm SB, Saft L, Andersson P, Kimby E, Wahlin BE, Christensson B, Sander B.

Oncoscience. 2014 Sep 4;1(8):550-7. eCollection 2014.


Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia.

Jaako P, Debnath S, Olsson K, Modlich U, Rothe M, Schambach A, Flygare J, Karlsson S.

Haematologica. 2014 Dec;99(12):1792-8. doi: 10.3324/haematol.2014.111195. Epub 2014 Sep 12.


Narcolepsy: let the patient's voice awaken us!

Flygare J, Parthasarathy S.

Am J Med. 2015 Jan;128(1):10-3. doi: 10.1016/j.amjmed.2014.05.037. Epub 2014 Jun 12. No abstract available.


Secondary stimulation from Bacillus Calmette-Guérin induced macrophages induce nitric oxide independent cell-death in bladder cancer cells.

Thiel T, Ryk C, Chatzakos V, Hallén Grufman K, Bavand-Chobot N, Flygare J, Wiklund NP, de Verdier PJ.

Cancer Lett. 2014 Jun 28;348(1-2):119-25. doi: 10.1016/j.canlet.2014.03.014. Epub 2014 Mar 18.


Tailoring small molecules for an allosteric site on procaspase-6.

Murray J, Giannetti AM, Steffek M, Gibbons P, Hearn BR, Cohen F, Tam C, Pozniak C, Bravo B, Lewcock J, Jaishankar P, Ly CQ, Zhao X, Tang Y, Chugha P, Arkin MR, Flygare J, Renslo AR.

ChemMedChem. 2014 Jan;9(1):73-7, 2. doi: 10.1002/cmdc.201300424. Epub 2013 Nov 20.


ZFP36L2 is required for self-renewal of early burst-forming unit erythroid progenitors.

Zhang L, Prak L, Rayon-Estrada V, Thiru P, Flygare J, Lim B, Lodish HF.

Nature. 2013 Jul 4;499(7456):92-6. doi: 10.1038/nature12215. Epub 2013 Jun 9.


Fetal hepatic progenitors support long-term expansion of hematopoietic stem cells.

Chou S, Flygare J, Lodish HF.

Exp Hematol. 2013 May;41(5):479-490.e4. doi: 10.1016/j.exphem.2013.02.003. Epub 2013 Feb 13.

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