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Items: 1 to 20 of 82

1.

High in vivo levels of adipsin lead to increased knee tissue degradation in osteoarthritis: data from humans and animal models.

Valverde-Franco G, Tardif G, Mineau F, Paré F, Lussier B, Fahmi H, Pelletier JP, Martel-Pelletier J.

Rheumatology (Oxford). 2018 Jun 29. doi: 10.1093/rheumatology/key181. [Epub ahead of print]

PMID:
29982662
2.

In vivo effect of opticin deficiency in cartilage in a surgically induced mouse model of osteoarthritis.

Farrán A, Valverde-Franco G, Tío L, Lussier B, Fahmi H, Pelletier JP, Bishop PN, Monfort J, Martel-Pelletier J.

Sci Rep. 2018 Jan 11;8(1):457. doi: 10.1038/s41598-017-18047-w.

3.

Corrigendum: ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis.

Lagares D, Ghassemi-Kakroodi P, Tremblay C, Santos A, Probst CK, Franklin A, Santos DM, Grasberger P, Ahluwalia N, Montesi SB, Shea BS, Black KE, Knipe R, Blati M, Baron M, Wu B, Fahmi H, Gandhi R, Pardo A, Selman M, Wu J, Pelletier JP, Martel-Pelletier J, Tager AM, Kapoor M.

Nat Med. 2017 Dec 7;23(12):1499. doi: 10.1038/nm1217-1499b.

PMID:
29216045
4.

ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis.

Lagares D, Ghassemi-Kakroodi P, Tremblay C, Santos A, Probst CK, Franklin A, Santos DM, Grasberger P, Ahluwalia N, Montesi SB, Shea BS, Black KE, Knipe R, Blati M, Baron M, Wu B, Fahmi H, Gandhi R, Pardo A, Selman M, Wu J, Pelletier JP, Martel-Pelletier J, Tager AM, Kapoor M.

Nat Med. 2017 Dec;23(12):1405-1415. doi: 10.1038/nm.4419. Epub 2017 Oct 23. Erratum in: Nat Med. 2017 Dec 7;23 (12 ):1499.

5.

Deletion of 12/15-lipoxygenase accelerates the development of aging-associated and instability-induced osteoarthritis.

Habouri L, El Mansouri FE, Ouhaddi Y, Lussier B, Pelletier JP, Martel-Pelletier J, Benderdour M, Fahmi H.

Osteoarthritis Cartilage. 2017 Oct;25(10):1719-1728. doi: 10.1016/j.joca.2017.07.001. Epub 2017 Jul 8.

PMID:
28694081
6.

Exacerbation of Aging-Associated and Instability-Induced Murine Osteoarthritis With Deletion of D Prostanoid Receptor 1, a Prostaglandin D2 Receptor.

Ouhaddi Y, Nebbaki SS, Habouri L, Afif H, Lussier B, Kapoor M, Narumiya S, Pelletier JP, Martel-Pelletier J, Benderdour M, Fahmi H.

Arthritis Rheumatol. 2017 Sep;69(9):1784-1795. doi: 10.1002/art.40160. Epub 2017 Aug 1.

7.

An overview of the role of lipid peroxidation-derived 4-hydroxynonenal in osteoarthritis.

Abusarah J, Bentz M, Benabdoune H, Rondon PE, Shi Q, Fernandes JC, Fahmi H, Benderdour M.

Inflamm Res. 2017 Aug;66(8):637-651. doi: 10.1007/s00011-017-1044-4. Epub 2017 Apr 26. Review.

PMID:
28447122
8.

Elucidating the Role of Protandim and 6-Gingerol in Protection Against Osteoarthritis.

Abusarah J, Benabdoune H, Shi Q, Lussier B, Martel-Pelletier J, Malo M, Fernandes JC, de Souza FP, Fahmi H, Benderdour M.

J Cell Biochem. 2017 May;118(5):1003-1013. doi: 10.1002/jcb.25659. Epub 2017 Jan 5.

PMID:
27463229
9.

The unfolded protein response genes in human osteoarthritic chondrocytes: PERK emerges as a potential therapeutic target.

Li YH, Tardif G, Hum D, Kapoor M, Fahmi H, Pelletier JP, Martel-Pelletier J.

Arthritis Res Ther. 2016 Jul 19;18:172. doi: 10.1186/s13075-016-1070-6.

10.

The role of resolvin D1 in the regulation of inflammatory and catabolic mediators in osteoarthritis.

Benabdoune H, Rondon EP, Shi Q, Fernandes J, Ranger P, Fahmi H, Benderdour M.

Inflamm Res. 2016 Aug;65(8):635-45. doi: 10.1007/s00011-016-0946-x. Epub 2016 Apr 7.

PMID:
27056390
11.

Systematic review of the association between chronic social stress and telomere length: A life course perspective.

Oliveira BS, Zunzunegui MV, Quinlan J, Fahmi H, Tu MT, Guerra RO.

Ageing Res Rev. 2016 Mar;26:37-52. doi: 10.1016/j.arr.2015.12.006. Epub 2015 Dec 28. Review.

PMID:
26732034
12.

Cellular Aging, Senescence and Autophagy Processes in Osteoarthritis.

Benderdour M, Martel-Pelletier J, Pelletier JP, Kapoor M, Zunzunegui MV, Fahmi H.

Curr Aging Sci. 2015;8(2):147-57. Review.

PMID:
26212056
13.

PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage.

Vasheghani F, Zhang Y, Li YH, Blati M, Fahmi H, Lussier B, Roughley P, Lagares D, Endisha H, Saffar B, Lajeunesse D, Marshall WK, Rampersaud YR, Mahomed NN, Gandhi R, Pelletier JP, Martel-Pelletier J, Kapoor M.

Ann Rheum Dis. 2015 Mar;74(3):569-78. doi: 10.1136/annrheumdis-2014-205743. Epub 2015 Jan 8.

14.

Cartilage-specific deletion of ephrin-B2 in mice results in early developmental defects and an osteoarthritis-like phenotype during aging in vivo.

Valverde-Franco G, Lussier B, Hum D, Wu J, Hamadjida A, Dancause N, Fahmi H, Kapoor M, Pelletier JP, Martel-Pelletier J.

Arthritis Res Ther. 2016 Mar 15;18:65. doi: 10.1186/s13075-016-0965-6.

15.

The in vivo effect of prophylactic subchondral bone protection of osteoarthritic synovial membrane in bone-specific Ephb4-overexpressing mice.

Valverde-Franco G, Hum D, Matsuo K, Lussier B, Pelletier JP, Fahmi H, Kapoor M, Martel-Pelletier J.

Am J Pathol. 2015 Feb;185(2):335-46. doi: 10.1016/j.ajpath.2014.10.004. Epub 2014 Nov 29.

PMID:
25453723
16.

Protocol for a systematic review of the association between chronic stress during the life course and telomere length.

Quinlan J, Tu MT, Langlois EV, Kapoor M, Ziegler D, Fahmi H, Zunzunegui MV.

Syst Rev. 2014 Apr 30;3:40. doi: 10.1186/2046-4053-3-40. Review.

17.

Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes.

El Mansouri FE, Nebbaki SS, Kapoor M, Afif H, Martel-Pelletier J, Pelletier JP, Benderdour M, Fahmi H.

Arthritis Res Ther. 2014 May 16;16(3):R113. doi: 10.1186/ar4564.

18.

Sorbitol-modified hyaluronic acid reduces oxidative stress, apoptosis and mediators of inflammation and catabolism in human osteoarthritic chondrocytes.

Mongkhon JM, Thach M, Shi Q, Fernandes JC, Fahmi H, Benderdour M.

Inflamm Res. 2014 Aug;63(8):691-701. doi: 10.1007/s00011-014-0742-4. Epub 2014 May 25.

PMID:
24858301
19.

New evidence implicating 4-hydroxynonenal in the pathogenesis of osteoarthritis in vivo.

Shi Q, Abusarah J, Zaouter C, Moldovan F, Fernandes JC, Fahmi H, Benderdour M.

Arthritis Rheumatol. 2014 Sep;66(9):2461-71. doi: 10.1002/art.38704.

20.

Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis.

Zhang Y, Vasheghani F, Li YH, Blati M, Simeone K, Fahmi H, Lussier B, Roughley P, Lagares D, Pelletier JP, Martel-Pelletier J, Kapoor M.

Ann Rheum Dis. 2015 Jul;74(7):1432-40. doi: 10.1136/annrheumdis-2013-204599. Epub 2014 Mar 20.

PMID:
24651621

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