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Comparing effects of CDK inhibition and E2F1/2 ablation on neuronal cell death pathways in vitro and after traumatic brain injury.

Aubrecht TG, Faden AI, Sabirzhanov B, Glaser EP, Roelofs BA, Polster BM, Makarevich O, Stoica BA.

Cell Death Dis. 2018 Nov 6;9(11):1121. doi: 10.1038/s41419-018-1156-y.


Sex Differences in Acute Neuroinflammation after Experimental Traumatic Brain Injury Are Mediated by Infiltrating Myeloid Cells.

Doran SJ, Ritzel RM, Glaser EP, Henry RJ, Faden AI, Loane DJ.

J Neurotrauma. 2018 Nov 16. doi: 10.1089/neu.2018.6019. [Epub ahead of print]


Inhibition of miR-155 Limits Neuroinflammation and Improves Functional Recovery After Experimental Traumatic Brain Injury in Mice.

Henry RJ, Doran SJ, Barrett JP, Meadows VE, Sabirzhanov B, Stoica BA, Loane DJ, Faden AI.

Neurotherapeutics. 2018 Sep 17. doi: 10.1007/s13311-018-0665-9. [Epub ahead of print]


MicroRNA-711-Induced Downregulation of Angiopoietin-1 Mediates Neuronal Cell Death.

Sabirzhanov B, Faden AI, Aubrecht T, Henry R, Glaser E, Stoica BA.

J Neurotrauma. 2018 Oct 15;35(20):2462-2481. doi: 10.1089/neu.2017.5572. Epub 2018 Jul 10.


Traumatic meningeal injury and repair mechanisms.

Loane DJ, Faden AI.

Nat Immunol. 2018 May;19(5):431-432. doi: 10.1038/s41590-018-0093-3. No abstract available.


Chronic Alterations in Systemic Immune Function after Traumatic Brain Injury.

Ritzel RM, Doran SJ, Barrett JP, Henry RJ, Ma EL, Faden AI, Loane DJ.

J Neurotrauma. 2018 Jul 1;35(13):1419-1436. doi: 10.1089/neu.2017.5399. Epub 2018 May 3.


Bidirectional brain-gut interactions and chronic pathological changes after traumatic brain injury in mice.

Ma EL, Smith AD, Desai N, Cheung L, Hanscom M, Stoica BA, Loane DJ, Shea-Donohue T, Faden AI.

Brain Behav Immun. 2017 Nov;66:56-69. doi: 10.1016/j.bbi.2017.06.018. Epub 2017 Jul 1.


NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury.

Barrett JP, Henry RJ, Villapol S, Stoica BA, Kumar A, Burns MP, Faden AI, Loane DJ.

J Neuroinflammation. 2017 Mar 24;14(1):65. doi: 10.1186/s12974-017-0843-4.


Microglial-derived microparticles mediate neuroinflammation after traumatic brain injury.

Kumar A, Stoica BA, Loane DJ, Yang M, Abulwerdi G, Khan N, Kumar A, Thom SR, Faden AI.

J Neuroinflammation. 2017 Mar 15;14(1):47. doi: 10.1186/s12974-017-0819-4.


Truncated TrkB.T1-Mediated Astrocyte Dysfunction Contributes to Impaired Motor Function and Neuropathic Pain after Spinal Cord Injury.

Matyas JJ, O'Driscoll CM, Yu L, Coll-Miro M, Daugherty S, Renn CL, Faden AI, Dorsey SG, Wu J.

J Neurosci. 2017 Apr 5;37(14):3956-3971. doi: 10.1523/JNEUROSCI.3353-16.2017. Epub 2017 Mar 7.


Cell cycle inhibition reduces inflammatory responses, neuronal loss, and cognitive deficits induced by hypobaria exposure following traumatic brain injury.

Skovira JW, Wu J, Matyas JJ, Kumar A, Hanscom M, Kabadi SV, Fang R, Faden AI.

J Neuroinflammation. 2016 Dec 1;13(1):299.


Endoplasmic Reticulum Stress and Disrupted Neurogenesis in the Brain Are Associated with Cognitive Impairment and Depressive-Like Behavior after Spinal Cord Injury.

Wu J, Zhao Z, Kumar A, Lipinski MM, Loane DJ, Stoica BA, Faden AI.

J Neurotrauma. 2016 Nov 1;33(21):1919-1935. Epub 2016 May 16.


NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury.

Kumar A, Barrett JP, Alvarez-Croda DM, Stoica BA, Faden AI, Loane DJ.

Brain Behav Immun. 2016 Nov;58:291-309. doi: 10.1016/j.bbi.2016.07.158. Epub 2016 Jul 28.


Cell cycle inhibition limits development and maintenance of neuropathic pain following spinal cord injury.

Wu J, Zhao Z, Zhu X, Renn CL, Dorsey SG, Faden AI.

Pain. 2016 Feb;157(2):488-503. doi: 10.1097/j.pain.0000000000000393.


Simulated Aeromedical Evacuation Exacerbates Experimental Brain Injury.

Skovira JW, Kabadi SV, Wu J, Zhao Z, DuBose J, Rosenthal R, Fiskum G, Faden AI.

J Neurotrauma. 2016 Jul 15;33(14):1292-302. doi: 10.1089/neu.2015.4189. Epub 2016 Jan 7.


Ablation of the transcription factors E2F1-2 limits neuroinflammation and associated neurological deficits after contusive spinal cord injury.

Wu J, Sabirzhanov B, Stoica BA, Lipinski MM, Zhao Z, Zhao S, Ward N, Yang D, Faden AI.

Cell Cycle. 2015;14(23):3698-712. doi: 10.1080/15384101.2015.1104436.


Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury.

Kumar A, Alvarez-Croda DM, Stoica BA, Faden AI, Loane DJ.

J Neurotrauma. 2016 Oct 1;33(19):1732-1750. Epub 2015 Dec 29.


miR-711 upregulation induces neuronal cell death after traumatic brain injury.

Sabirzhanov B, Stoica BA, Zhao Z, Loane DJ, Wu J, Dorsey SG, Faden AI.

Cell Death Differ. 2016 Apr;23(4):654-68. doi: 10.1038/cdd.2015.132. Epub 2015 Oct 16.


S100B inhibition reduces behavioral and pathologic changes in experimental traumatic brain injury.

Kabadi SV, Stoica BA, Zimmer DB, Afanador L, Duffy KB, Loane DJ, Faden AI.

J Cereb Blood Flow Metab. 2015 Dec;35(12):2010-20. doi: 10.1038/jcbfm.2015.165. Epub 2015 Jul 8.


Progressive inflammation-mediated neurodegeneration after traumatic brain or spinal cord injury.

Faden AI, Wu J, Stoica BA, Loane DJ.

Br J Pharmacol. 2016 Feb;173(4):681-91. doi: 10.1111/bph.13179. Epub 2015 Jun 12. Review.

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