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Items: 1 to 20 of 2046


Eremomycin pyrrolidide: a novel semisynthetic glycopeptide with improved chemotherapeutic properties.

Olsufyeva EN, Shchekotikhin AE, Bychkova EN, Pereverzeva ER, Treshalin ID, Mirchink EP, Isakova EB, Chernobrovkin MG, Kozlov RS, Dekhnich AV, Preobrazhenskaya MN.

Drug Des Devel Ther. 2018 Sep 10;12:2875-2885. doi: 10.2147/DDDT.S173923. eCollection 2018.


Profile of atezolizumab in the treatment of metastatic non-small-cell lung cancer: patient selection and perspectives.

Facchinetti F, Bordi P, Leonetti A, Buti S, Tiseo M.

Drug Des Devel Ther. 2018 Sep 10;12:2857-2873. doi: 10.2147/DDDT.S124380. eCollection 2018. Review.


Anti-HER2 functionalized graphene oxide as survivin-siRNA delivery carrier inhibits breast carcinoma growth in vitro and in vivo.

Wang X, Sun Q, Cui C, Li J, Wang Y.

Drug Des Devel Ther. 2018 Sep 7;12:2841-2855. doi: 10.2147/DDDT.S169430. eCollection 2018.


Alpha lipoic acid combined with epalrestat: a therapeutic option for patients with diabetic peripheral neuropathy.

Wang X, Lin H, Xu S, Jin Y, Zhang R.

Drug Des Devel Ther. 2018 Sep 7;12:2827-2840. doi: 10.2147/DDDT.S168878. eCollection 2018. Review.


Preliminary study on conjugation of formononetin with multiwalled carbon nanotubes for inducing apoptosis via ROS production in HeLa cells.

Guo B, Liao C, Liu X, Yi J.

Drug Des Devel Ther. 2018 Sep 7;12:2815-2826. doi: 10.2147/DDDT.S169767. eCollection 2018.


Macrocyclic lactones inhibit nasopharyngeal carcinoma cells proliferation through PAK1 inhibition and reduce in vivo tumor growth.

Gallardo F, Mariamé B, Gence R, Tilkin-Mariamé AF.

Drug Des Devel Ther. 2018 Sep 7;12:2805-2814. doi: 10.2147/DDDT.S172538. eCollection 2018.


The effect of food and liquid pH on the integrity of enteric-coated beads from cysteamine bitartrate delayed-release capsules.

Pavloff N, Hauser TA, Williams C, Isbell SL, Cadieux B, Johnson M.

Drug Des Devel Ther. 2018 Sep 6;12:2795-2804. doi: 10.2147/DDDT.S174928. eCollection 2018.


Astragaloside IV/lncRNA-TUG1/TRAF5 signaling pathway participates in podocyte apoptosis of diabetic nephropathy rats.

Lei X, Zhang L, Li Z, Ren J.

Drug Des Devel Ther. 2018 Sep 6;12:2785-2793. doi: 10.2147/DDDT.S166525. eCollection 2018.


Efficacy and safety of a fixed-dose combination of nimesulide/pantoprazole compared to naproxen/esomeprazole for pain relief in patients with osteoarticular diseases and dyspeptic symptoms.

Scheinberg M, Pott Júnior H, Macêdo EA, Bocchi de Oliveira MF, Ecclissato C, Amazonas RB.

Drug Des Devel Ther. 2018 Sep 6;12:2775-2783. doi: 10.2147/DDDT.S172068. eCollection 2018.


Are laboratory parameter (biomarker) values similar to the healthy volunteer reference range in all patient populations?

Brott DA, Goodman MJ, Hermann RP, Merz M, Calvo R, Poorkhalkali N, Kiazand A.

Drug Des Devel Ther. 2018 Sep 6;12:2757-2773. doi: 10.2147/DDDT.S173671. eCollection 2018.


Safety and efficacy of elbasvir/grazoprevir for the treatment of chronic hepatitis C: current evidence.

Morikawa K, Nakamura A, Shimazaki T, Sakamoto N.

Drug Des Devel Ther. 2018 Sep 5;12:2749-2756. doi: 10.2147/DDDT.S133697. eCollection 2018. Review.


Dingchuan tang essential oil inhibits the production of inflammatory mediators via suppressing the IRAK/NF-κB, IRAK/AP-1, and TBK1/IRF3 pathways in lipopolysaccharide-stimulated RAW264.7 cells.

Zhang Y, Guo H, Cheng BC, Su T, Fu XQ, Li T, Zhu PL, Tse KW, Pan SY, Yu ZL.

Drug Des Devel Ther. 2018 Sep 4;12:2731-2748. doi: 10.2147/DDDT.S160645. eCollection 2018.


17β-estradiol ameliorates oxidative stress and blue light-emitting diode-induced retinal degeneration by decreasing apoptosis and enhancing autophagy.

Wei Q, Liang X, Peng Y, Yu D, Zhang R, Jin H, Fan J, Cai W, Ren C, Yu J.

Drug Des Devel Ther. 2018 Sep 4;12:2715-2730. doi: 10.2147/DDDT.S176349. eCollection 2018.


Fasudil inhibits actin polymerization and collagen synthesis and induces apoptosis in human urethral scar fibroblasts via the Rho/ROCK pathway.

Li XD, Wu YP, Chen SH, Liang YC, Lin TT, Lin T, Wei Y, Xue XY, Zheng QS, Xu N.

Drug Des Devel Ther. 2018 Sep 3;12:2707-2713. doi: 10.2147/DDDT.S156095. eCollection 2018.


The total alkaloids from Coptis chinensis Franch improve cognitive deficits in type 2 diabetic rats.

Li JC, Shen XF, Shao JA, Tao MM, Gu J, Li J, Huang N.

Drug Des Devel Ther. 2018 Aug 31;12:2695-2706. doi: 10.2147/DDDT.S171025. eCollection 2018.


Asenapine pharmacokinetics and tolerability in a pediatric population.

Dogterom P, Riesenberg R, de Greef R, Dennie J, Johnson M, Pilla Reddy V, Miltenburg AM, Findling RL, Jakate A, Carrothers TJ, Troyer MD.

Drug Des Devel Ther. 2018 Aug 30;12:2677-2693. doi: 10.2147/DDDT.S171475. eCollection 2018.


Profile of pitolisant in the management of narcolepsy: design, development, and place in therapy.

Romigi A, Vitrani G, Lo Giudice T, Centonze D, Franco V.

Drug Des Devel Ther. 2018 Aug 30;12:2665-2675. doi: 10.2147/DDDT.S101145. eCollection 2018. Review.


Inhibiting eEF-2 kinase-mediated autophagy enhanced the cytocidal effect of AKT inhibitor on human nasopharyngeal carcinoma.

Zhao YY, Tian Y, Liu L, Zhan JH, Hou X, Chen X, Zhou T, Huang Y, Zhang L.

Drug Des Devel Ther. 2018 Aug 29;12:2655-2663. doi: 10.2147/DDDT.S169952. eCollection 2018.


A novel multifunctional anti-CEA-IL15 molecule displays potent antitumor activities.

Liu Y, Wang Y, Xing J, Li Y, Liu J, Wang Z.

Drug Des Devel Ther. 2018 Aug 29;12:2645-2654. doi: 10.2147/DDDT.S166373. eCollection 2018.


Efficient drug delivery of β-estradiol encapsulated in Zn-metal-organic framework nanostructures by microwave-assisted coprecipitation method.

Ranjbar M, Pardakhty A, Amanatfard A, Asadipour A.

Drug Des Devel Ther. 2018 Aug 28;12:2635-2643. doi: 10.2147/DDDT.S173324. eCollection 2018.

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