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Items: 1 to 20 of 43


Human recombinant fsh induces chemoresistance in human breast cancer cells via hif-1α activation.

Bergandi L, Canosa S, Pittatore G, Silvagno F, Doublier S, Gennarelli G, Benedetto C, Revelli A.

Biol Reprod. 2019 Apr 2. pii: ioz050. doi: 10.1093/biolre/ioz050. [Epub ahead of print]


Pyruvate Treatment Restores the Effectiveness of Chemotherapeutic Agents in Human Colon Adenocarcinoma and Pleural Mesothelioma Cells.

Mungo E, Bergandi L, Salaroglio IC, Doublier S.

Int J Mol Sci. 2018 Nov 10;19(11). pii: E3550. doi: 10.3390/ijms19113550.


Soluble CD40 ligand directly alters glomerular permeability and may act as a circulating permeability factor in FSGS.

Doublier S, Zennaro C, Musante L, Spatola T, Candiano G, Bruschi M, Besso L, Cedrino M, Carraro M, Ghiggeri GM, Camussi G, Lupia E.

PLoS One. 2017 Nov 20;12(11):e0188045. doi: 10.1371/journal.pone.0188045. eCollection 2017.


Carbon in intimate contact with quartz reduces the biological activity of crystalline silica dusts.

Ghiazza M, Tomatis M, Doublier S, Grendene F, Gazzano E, Ghigo D, Fubini B.

Chem Res Toxicol. 2013 Jan 18;26(1):46-54. doi: 10.1021/tx300299v. Epub 2012 Nov 2.


HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast.

Doublier S, Belisario DC, Polimeni M, Annaratone L, Riganti C, Allia E, Ghigo D, Bosia A, Sapino A.

BMC Cancer. 2012 Jan 4;12:4. doi: 10.1186/1471-2407-12-4.


Pentosan polysulfate inhibits atherosclerosis in Watanabe heritable hyperlipidemic rabbits: differential modulation of metalloproteinase-2 and -9.

Lupia E, Zheng F, Grosjean F, Tack I, Doublier S, Elliot SJ, Vlassara H, Striker GE.

Lab Invest. 2012 Feb;92(2):236-45. doi: 10.1038/labinvest.2011.154. Epub 2011 Oct 31.


Antioxidants prevent the RhoA inhibition evoked by crocidolite asbestos in human mesothelial and mesothelioma cells.

Aldieri E, Riganti C, Silvagno F, Orecchia S, Betta PG, Doublier S, Gazzano E, Polimeni M, Bosia A, Ghigo D.

Am J Respir Cell Mol Biol. 2011 Sep;45(3):625-31. doi: 10.1165/rcmb.2010-0089OC. Epub 2011 Jan 21.


Pleiotropic effects of cardioactive glycosides.

Riganti C, Campia I, Kopecka J, Gazzano E, Doublier S, Aldieri E, Bosia A, Ghigo D.

Curr Med Chem. 2011;18(6):872-85. Review.


Estrogens and progression of diabetic kidney damage.

Doublier S, Lupia E, Catanuto P, Elliot SJ.

Curr Diabetes Rev. 2011 Jan;7(1):28-34. Review.


Testosterone and 17β-estradiol have opposite effects on podocyte apoptosis that precedes glomerulosclerosis in female estrogen receptor knockout mice.

Doublier S, Lupia E, Catanuto P, Periera-Simon S, Xia X, Korach K, Berho M, Elliot SJ, Karl M.

Kidney Int. 2011 Feb;79(4):404-13. doi: 10.1038/ki.2010.398. Epub 2010 Oct 20.


Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cells.

Kopecka J, Campia I, Brusa D, Doublier S, Matera L, Ghigo D, Bosia A, Riganti C.

J Cell Mol Med. 2011 Jul;15(7):1492-504. doi: 10.1111/j.1582-4934.2010.01137.x.


Fluoride effects: the two faces of janus.

Gazzano E, Bergandi L, Riganti C, Aldieri E, Doublier S, Costamagna C, Bosia A, Ghigo D.

Curr Med Chem. 2010;17(22):2431-41. Review.


Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium-dependent activation of HIF-1alpha and P-glycoprotein overexpression.

Riganti C, Doublier S, Viarisio D, Miraglia E, Pescarmona G, Ghigo D, Bosia A.

Br J Pharmacol. 2009 Apr;156(7):1054-66. doi: 10.1111/j.1476-5381.2009.00117.x. Epub 2009 Mar 9.


17 beta-estradiol and tamoxifen upregulate estrogen receptor beta expression and control podocyte signaling pathways in a model of type 2 diabetes.

Catanuto P, Doublier S, Lupia E, Fornoni A, Berho M, Karl M, Striker GE, Xia X, Elliot S.

Kidney Int. 2009 Jun;75(11):1194-1201. doi: 10.1038/ki.2009.69. Epub 2009 Mar 11.


RhoA silencing reverts the resistance to doxorubicin in human colon cancer cells.

Doublier S, Riganti C, Voena C, Costamagna C, Aldieri E, Pescarmona G, Ghigo D, Bosia A.

Mol Cancer Res. 2008 Oct;6(10):1607-20. doi: 10.1158/1541-7786.MCR-08-0251.


Statins-mediated inhibition of rho GTPases as a potential tool in anti-tumor therapy.

Riganti C, Aldieri E, Doublier S, Bosia A, Ghigo D.

Mini Rev Med Chem. 2008 Jun;8(6):609-18. Review.


Activation of nuclear factor-kappa B pathway by simvastatin and RhoA silencing increases doxorubicin cytotoxicity in human colon cancer HT29 cells.

Riganti C, Doublier S, Costamagna C, Aldieri E, Pescarmona G, Ghigo D, Bosia A.

Mol Pharmacol. 2008 Aug;74(2):476-84. doi: 10.1124/mol.108.045286. Epub 2008 May 7.


Asbestos induces doxorubicin resistance in MM98 mesothelioma cells via HIF-1alpha.

Riganti C, Doublier S, Aldieri E, Orecchia S, Betta PG, Gazzano E, Ghigo D, Bosia A.

Eur Respir J. 2008 Aug;32(2):443-51. doi: 10.1183/09031936.00090407. Epub 2008 Apr 2.


The NADPH oxidase inhibitor apocynin induces nitric oxide synthesis via oxidative stress.

Riganti C, Costamagna C, Doublier S, Miraglia E, Polimeni M, Bosia A, Ghigo D.

Toxicol Appl Pharmacol. 2008 May 1;228(3):277-85. doi: 10.1016/j.taap.2007.12.013. Epub 2007 Dec 23.

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