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Items: 1 to 20 of 354

1.

Drugs in space: Pharmacokinetics and pharmacodynamics in astronauts.

Kast J, Yu Y, Seubert CN, Wotring VE, Derendorf H.

Eur J Pharm Sci. 2017 May 19. pii: S0928-0987(17)30253-1. doi: 10.1016/j.ejps.2017.05.025. [Epub ahead of print]

PMID:
28533143
2.

Professor Yuichi Sugiyama: A Brilliant, Creative, Amicable, Charming and Humorous Pharmaceutical Scientist.

Kusuhara H, Obach RS, Rostami-Hodjegan A, Pang KS, Hammarlund-Udenaes M, Derendorf H, Artursson P, Huang SM, Suzuki H, Terasaki T.

J Pharm Sci. 2017 May 4. pii: S0022-3549(17)30343-X. doi: 10.1016/j.xphs.2017.04.072. [Epub ahead of print] No abstract available.

PMID:
28479350
3.

Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis.

Jadhav SB, Khaowroongrueng V, Fueth M, Otteneder MB, Richter W, Derendorf H.

J Pharm Sci. 2017 Apr 13. pii: S0022-3549(17)30219-8. doi: 10.1016/j.xphs.2017.03.033. [Epub ahead of print]

PMID:
28414146
4.

Lung Tissue Concentrations of Pyrazinamide among Patients with Drug-Resistant Pulmonary Tuberculosis.

Kempker RR, Heinrichs MT, Nikolaishvili K, Sabulua I, Bablishvili N, Gogishvili S, Avaliani Z, Tukvadze N, Little B, Bernheim A, Read TD, Guarner J, Derendorf H, Peloquin CA, Blumberg HM, Vashakidze S.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e00226-17. doi: 10.1128/AAC.00226-17. Print 2017 Jun.

PMID:
28373198
5.

A need to revisit clinical breakpoints of tigecycline: effect of atypical non-linear plasma protein binding.

Singh RS, Mukker JK, Drescher SK, Deitchman AN, Derendorf H.

Int J Antimicrob Agents. 2017 Apr;49(4):449-455. doi: 10.1016/j.ijantimicag.2016.12.008. Epub 2017 Feb 22.

PMID:
28237830
6.

Prediction of in vivo and in vitro infection model results using a semimechanistic model of avibactam and aztreonam combination against multidrug resistant organisms.

Sy S, Zhuang L, Xia H, Beaudoin ME, Schuck VJ, Derendorf H.

CPT Pharmacometrics Syst Pharmacol. 2017 Mar;6(3):197-207. doi: 10.1002/psp4.12159. Epub 2017 Feb 1.

7.

Potentiation of ceftazidime by avibactam against β-lactam-resistant Pseudomonas aeruginosa in an in vitro infection model.

Sy SK, Zhuang L, Beaudoin ME, Kircher P, Tabosa MA, Cavalcanti NC, Grunwitz C, Pieper S, Schuck VJ, Nichols WW, Derendorf H.

J Antimicrob Chemother. 2017 Apr 1;72(4):1109-1117. doi: 10.1093/jac/dkw535.

PMID:
28077672
8.

Utility of Microdialysis in Infectious Disease Drug Development and Dose Optimization.

Deitchman AN, Heinrichs MT, Khaowroongrueng V, Jadhav SB, Derendorf H.

AAPS J. 2017 Mar;19(2):334-342. doi: 10.1208/s12248-016-0020-1. Epub 2016 Dec 9.

PMID:
27943149
9.

Ceftobiprole medocaril (BAL-5788) for the treatment of complicated skin infections.

Deitchman A, de Jong D, Barbour A, Derendorf H.

Expert Rev Anti Infect Ther. 2016 Oct 2. [Epub ahead of print]

PMID:
27690689
10.

Microdialysis of Large Molecules.

Jadhav SB, Khaowroongrueng V, Derendorf H.

J Pharm Sci. 2016 Nov;105(11):3233-3242. doi: 10.1016/j.xphs.2016.08.016. Epub 2016 Sep 23. Review.

PMID:
27671236
11.

Role of Divalent Metal Ions in Atypical Nonlinear Plasma Protein Binding Behavior of Tigecycline.

Singh RS, Mukker JK, Deitchman AN, Drescher SK, Derendorf H.

J Pharm Sci. 2016 Nov;105(11):3409-3414. doi: 10.1016/j.xphs.2016.07.013. Epub 2016 Sep 9.

PMID:
27616672
12.

Ciclesonide: A Pro-Soft Drug Approach for Mitigation of Side Effects of Inhaled Corticosteroids.

Mukker JK, Singh RS, Derendorf H.

J Pharm Sci. 2016 Sep;105(9):2509-14. doi: 10.1016/j.xphs.2016.05.004. Epub 2016 Jun 21.

PMID:
27339407
13.

Quantitation of the impact of CYP3A5 A6986G polymorphism on quetiapine pharmacokinetics by simulation of target attainment.

Shilbayeh SA, Sy SK, Melhem M, Zmeili R, Derendorf H.

Clin Pharmacol Drug Dev. 2015 Sep;4(5):387-94. doi: 10.1002/cpdd.172. Epub 2015 Jan 12.

PMID:
27137148
14.

In vitro pharmacokinetics/pharmacodynamics of the combination of avibactam and aztreonam against MDR organisms.

Sy SK, Beaudoin ME, Zhuang L, Löblein KI, Lux C, Kissel M, Tremmel R, Frank C, Strasser S, Heuberger JA, Mulder MB, Schuck VJ, Derendorf H.

J Antimicrob Chemother. 2016 Jul;71(7):1866-80. doi: 10.1093/jac/dkw082. Epub 2016 Apr 21.

PMID:
27107096
15.

A Tribute to Dr. Marcus E. Brewster: October 14, 1957-September 15, 2014.

Augustijns P, Loftsson T, Davies M, Derendorf H, Mesens J, Verreck G.

J Pharm Sci. 2016 Sep;105(9):2466-7. doi: 10.1016/j.xphs.2016.02.001. Epub 2016 Mar 22. No abstract available.

PMID:
27012223
16.

Race-Specific Pharmacodynamic Model of Propofol-Induced Loss of Consciousness.

Lampotang S, Lizdas DE, Derendorf H, Gravenstein N, Lok B, Quarles JP.

J Clin Pharmacol. 2016 Sep;56(9):1141-50. doi: 10.1002/jcph.716. Epub 2016 Mar 28.

PMID:
26865382
17.

Gentamicin dosing strategy in patients with end-stage renal disease receiving haemodialysis: evaluation using a semi-mechanistic pharmacokinetic/pharmacodynamic model.

Zhuang L, He Y, Xia H, Liu Y, Sy SK, Derendorf H.

J Antimicrob Chemother. 2016 Apr;71(4):1012-21. doi: 10.1093/jac/dkv428. Epub 2015 Dec 24.

PMID:
26702923
18.

Pharmacokinetics and pharmacodynamics in antibiotic dose optimization.

Sy SK, Zhuang L, Derendorf H.

Expert Opin Drug Metab Toxicol. 2016;12(1):93-114. doi: 10.1517/17425255.2016.1123250. Epub 2015 Dec 14. Review.

PMID:
26652832
19.

Theory and Application of Microdialysis in Pharmacokinetic Studies.

Zhuang L, Xia H, Gu Y, Derendorf H, Li Y, Liu C.

Curr Drug Metab. 2015;16(10):919-31. Review.

PMID:
26264199
20.

Simultaneous Characterization of Intravenous and Oral Pharmacokinetics of Lychnopholide in Rats by Transit Compartment Model.

Lachi-Silva L, Sy SK, Voelkner A, de Sousa JP, Lopes JL, Silva DB, Lopes NP, Kimura E, Derendorf H, Diniz A.

Planta Med. 2015 Aug;81(12-13):1121-7. doi: 10.1055/s-0035-1546214. Epub 2015 Jul 28.

PMID:
26218336

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